Zobrazeno 1 - 10
of 91
pro vyhledávání: '"Yoshiro Saimi"'
Autor:
Yoshiro Saimi, Ching Kung, W. John Haynes, Stephen H. Loukin, Andriy Anishkin, Xin-Liang Zhou, Zhenwei Su
Publikováno v:
Proceedings of the National Academy of Sciences. 104:19607-19612
Transient receptor potential (TRP) channels found in animals, protists, and fungi are primary chemo-, thermo-, or mechanosensors. Current research emphasizes the characteristics of individual channels in each animal TRP subfamily but not the mechanis
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f4dac0d48e5bb56d327061b3c55edb28
https://doi.org/10.1073/pnas.0708584104
https://doi.org/10.1073/pnas.0708584104
Autor:
Ching Kung, Stephen H. Loukin, Xin-Liang Zhou, Yoshiro Saimi, Zhenwei Su, W. John Haynes, Andriy Anishkin, Eric M. Friske
Publikováno v:
Proceedings of the National Academy of Sciences. 104:15555-15559
Transient receptor potential (TRP) channels are first elements in sensing chemicals, heat, and force and are widespread among protists and fungi as well as animals. Despite their importance, the arrangement and roles of the amino acids that constitut
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a3af416a5009b1723eb4fab7e63f50c1
https://doi.org/10.1073/pnas.0704039104
https://doi.org/10.1073/pnas.0704039104
Publikováno v:
Journal of Biological Chemistry. 282:24294-24301
Prokaryotic ion channels have been valuable in providing structural models for understanding ion filtration and channel-gating mechanisms. However, their functional examinations have remained rare and usually been carried out by incorporating purifie
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c40d84167eb371ebdeca73cca2ec521a
https://doi.org/10.1074/jbc.m703618200
https://doi.org/10.1074/jbc.m703618200
Autor:
Ching Kung, Stephen H. Loukin, Mario Meng-Chiang Kuo, Xin-Liang Zhou, W. John Haynes, Yoshiro Saimi
Publikováno v:
The Journal of General Physiology
A survey of the currently available genomes shows that K+ channels are found in most free-living bacteria, archaea, and protists, indicating early evolution before the divergences of the three major domains of life. Though vertically descended from t
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::365d8896c390d955e96137cb53c4e703
https://doi.org/10.1085/jgp.200509261
https://doi.org/10.1085/jgp.200509261
Publikováno v:
Proceedings of the National Academy of Sciences. 99:15717-15722
There are very few molecules known to transport Mg 2+ in eukaryotes. The membrane of Paramecium tetraurelia passes a large Mg 2+ -selective current and exhibits a corresponding backward swimming behavior. Both are missing in a group of mutants called
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e88ebc3e53390a09ea12b32020d42999
https://doi.org/10.1073/pnas.242603999
https://doi.org/10.1073/pnas.242603999
Publikováno v:
Proceedings of the National Academy of Sciences. 99:1926-1930
Non-targeted mutagenesis studies of the yeast K + channel, TOK1, have led to identification of functional domains common to other cation channels as well as those so far not found in other channels. Among the latter is the ability of the carboxyl tai
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::6f444cfd9d19d8fd4f602b680c9eb5da
https://doi.org/10.1073/pnas.042538599
https://doi.org/10.1073/pnas.042538599
Publikováno v:
Bacterial Ion Channels and Their Eukaryotic Homologs
K+ is apparently crucial in dealing with biological water on Earth, even today. Dehydration, i.e., external osmotic upshift, demands an adjustment of cellular osmolarity, lest the pressure difference break the membrane. In cases more thoroughly studi
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::b5a81b82f38d96a8676c6c746878724c
https://doi.org/10.1128/9781555816452.ch1
https://doi.org/10.1128/9781555816452.ch1
Publikováno v:
The Journal of Eukaryotic Microbiology. 47:11-14
Paramecium continues to be used to study motility, behavior, exocytosis, and the relationship between the germ and the somatic nuclei. Recent progress in molecular genetics is described. Toward cloning genes that correspond to mutant phenotypes, a me
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::d9b209133d4f6e86999f39c16e4d0113
https://doi.org/10.1111/j.1550-7408.2000.tb00003.x
https://doi.org/10.1111/j.1550-7408.2000.tb00003.x
Publikováno v:
Gene. 231:21-32
Ca2+/calmodulin (CaM) regulates various physiological processes in a wide variety of organisms, metazoa and protists alike. To better understand Ca2+/CaM-dependent processes, particularly those with membrane-associated components, we studied Ca2+/CaM
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::74e8ea57b2babcc5b1367e13d8c29ddc
https://doi.org/10.1016/s0378-1119(99)00101-8
https://doi.org/10.1016/s0378-1119(99)00101-8
Autor:
Yoshiro Saimi, Brian Vaillant, Xin Liang Zhou, Stephen H. Loukin, Edgar P. Spalding, Ching Kung
Publikováno v:
The EMBO Journal. 16:4817-4825
YKC1 (TOK1, DUK1, YORK) encodes the outwardly rectifying K+ channel of the yeast plasma membrane. Non-targeted mutations of YKC1 were isolated by their ability to completely block proliferation when expressed in yeast. All such mutations examined occ
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::3ab31d71fb828c1eeb0a1b2bbb93e82b
https://doi.org/10.1093/emboj/16.16.4817
https://doi.org/10.1093/emboj/16.16.4817