Zobrazeno 1 - 10
of 151
pro vyhledávání: '"Yoshiro Maezawa"'
Autor:
Ryoichi Ishibashi, Masaya Koshizaka, Yoko Takatsuna, Tomoaki Tatsumi, Yoshiro Maezawa, Yuki Shiko, Yosuke Inaba, Yohei Kawasaki, Yusuke Kashiwagi, Eiryo Kawakami, Shuichi Yamamoto, Koutaro Yokote
Publikováno v:
Journal of Diabetes Investigation, Vol 15, Iss 9, Pp 1231-1238 (2024)
Abstract Aims/Introduction Severe diabetic macular edema (DME) is often resistant to anti‐vascular endothelial growth factor therapy. Steroids are particularly effective at reducing edema by suppressing inflammation; they are also used as an altern
Externí odkaz:
https://doaj.org/article/b4f69585b8044506bf8a7df97b4fd7f3
Autor:
Sudip Kumar Paul, Motohiko Oshima, Ashwini Patil, Masamitsu Sone, Hisaya Kato, Yoshiro Maezawa, Hiyori Kaneko, Masaki Fukuyo, Bahityar Rahmutulla, Yasuo Ouchi, Kyoko Tsujimura, Mahito Nakanishi, Atsushi Kaneda, Atsushi Iwama, Koutaro Yokote, Koji Eto, Naoya Takayama
Publikováno v:
Nature Communications, Vol 15, Iss 1, Pp 1-17 (2024)
Abstract The underlying mechanisms of atherosclerosis, the second leading cause of death among Werner syndrome (WS) patients, are not fully understood. Here, we establish an in vitro co-culture system using macrophages (iMφs), vascular endothelial c
Externí odkaz:
https://doaj.org/article/4b3e5780bad44b1cb65ac33d2b450617
Autor:
Mayumi Shoji, Naoya Teramoto, Takahiro Ishikawa, Aiko Hayashi, Ai Matsumoto, Hidetoshi Ochiai, Ayano Yamaguchi, Yukari Maeda, Atsushi Takasaki, Chihiro Hiraga, Shintaro Ide, Kana Ide, Masashi Yamamoto, Yoshiro Maezawa, Ayako Shigeta, Seiichiro Sakao, Takuji Suzuki, Misuzu Yahaba, Toshihumi Taniguchi, Hidetoshi Igari, Koutaro Yokote, Masaya Koshizaka
Publikováno v:
Endocrine and Metabolic Science, Vol 16, Iss , Pp 100196- (2024)
Introduction: To elucidate factors associated with severe disease in patients with coronavirus disease 2019 (COVID-19) pneumonia complicated with diabetes mellitus. Methods: Among patients with COVID-19 pneumonia hospitalized from January to Septembe
Externí odkaz:
https://doaj.org/article/c53ef8aaa5d041a4b3cf721a4fb71a16
Publikováno v:
Biophysics and Physicobiology, Vol 21 (2024)
During embryogenesis, human hematopoietic stem cells (HSCs) first emerge in the aorta-gonad-mesonephros (AGM) region via transformation of specialized hemogenic endothelial (HE) cells into premature HSC precursors. This process is termed endothelial-
Externí odkaz:
https://doaj.org/article/9cc50b6a729a4406afa2add785e043ce
Autor:
Ryoichi Ishibashi, Kiichi Hirayama, Suzuka Watanabe, Kosuke Okano, Yuta Kuroda, Yusuke Baba, Takuma Kanayama, Chiho Ito, Keisuke Kasahara, Saki Aiba, Ryo Iga, Ryohei Ohtani, Yosuke Inaba, Masaya Koshizaka, Yoshiro Maezawa, Koutaro Yokote
Publikováno v:
Journal of Diabetes Investigation, Vol 14, Iss 12, Pp 1419-1422 (2023)
Abstract Mitochondrial dysfunction causes maternally inherited deafness and diabetes (MIDD). Herein, we report improved glycemic control in a 47‐year‐old Japanese woman with MIDD using imeglimin without major adverse effects. Biochemical tests an
Externí odkaz:
https://doaj.org/article/fa9a8485ccbf4def83e5c70a19fd0bb9
Publikováno v:
Journal of Diabetes Investigation, Vol 14, Iss 9, Pp 1041-1044 (2023)
Externí odkaz:
https://doaj.org/article/cfa1101fa75a44bc82c9d1bfb71c77fc
Autor:
Yoshiro Maezawa, Yusuke Endo, Satomi Kono, Tomohiro Ohno, Yuumi Nakamura, Naoya Teramoto, Ayano Yamaguchi, Kazuto Aono, Takuya Minamizuka, Hisaya Kato, Takahiro Ishikawa, Masaya Koshizaka, Minoru Takemoto, Toshinori Nakayama, Koutaro Yokote
Publikováno v:
Journal of Diabetes Investigation, Vol 14, Iss 9, Pp 1136-1139 (2023)
Abstract Psoriasis is a chronic inflammatory skin disease that is associated with obesity and myocardial infarction. Obesity‐induced changes in lipid metabolism promote T helper 17 (Th17) cell differentiation, which in turn promotes chronic inflamm
Externí odkaz:
https://doaj.org/article/f10891cbf79a443c918d56299715ba3c
Autor:
Sho Sugawara, Ryo Okada, Tze Mun Loo, Hisamichi Tanaka, Kenichi Miyata, Masatomo Chiba, Hiroko Kawasaki, Kaoru Katoh, Shizuo Kaji, Yoshiro Maezawa, Koutaro Yokote, Mizuho Nakayama, Masanobu Oshima, Koji Nagao, Chikashi Obuse, Satoshi Nagayama, Keiyo Takubo, Akira Nakanishi, Masato T. Kanemaki, Eiji Hara, Akiko Takahashi
Publikováno v:
Communications Biology, Vol 5, Iss 1, Pp 1-13 (2022)
The levels of catalytic subunit of the RNaseH2 enzyme, RNAseH2A, decrease during senescence promoting nucleotide accumulation and a senescence-associated secretory phenotype.
Externí odkaz:
https://doaj.org/article/c3317a7c0604439689709bd59c372b06
Autor:
Tatsuya Nagai, Hirotaka Yokouchi, Gen Miura, Masaya Koshizaka, Yoshiro Maezawa, Toshiyuki Oshitari, Koutaro Yokote, Takayuki Baba
Publikováno v:
BMC Ophthalmology, Vol 22, Iss 1, Pp 1-7 (2022)
Abstract Background Werner syndrome is a rare, autosomal recessive disorder characterised by premature aging. It is a typical hereditary progeroid syndrome that can be difficult to diagnose owing to its rarity and the similarity of some of its sympto
Externí odkaz:
https://doaj.org/article/6c9549656ef343e8b2362f33295d69bb
Autor:
Jumpei Shoda, Shigeru Tanaka, Keishi Etori, Koto Hattori, Tadamichi Kasuya, Kei Ikeda, Yuko Maezawa, Akira Suto, Kotaro Suzuki, Junichi Nakamura, Yoshiro Maezawa, Minoru Takemoto, Christer Betsholtz, Koutaro Yokote, Seiji Ohtori, Hiroshi Nakajima
Publikováno v:
Arthritis Research & Therapy, Vol 24, Iss 1, Pp 1-12 (2022)
Abstract Objectives Methotrexate (MTX) is an anchor drug for the treatment of rheumatoid arthritis (RA). However, the precise mechanisms by which MTX stalls RA progression and alleviates the ensuing disease effects remain unknown. The aim of the pres
Externí odkaz:
https://doaj.org/article/64af3118d6694e818a90d68efd9d7adb