Zobrazeno 1 - 10
of 11
pro vyhledávání: '"Yoshio Kuwayama"'
Autor:
Dong Yin, Wangrong G Yang, Jack Weissberg, Catherine B Goff, Weikai Chen, Yoshio Kuwayama, Amanda Leiter, Hongtao Xing, Antonie Meixel, Daria Gaut, Fikret Kirkbir, David Sawcer, P Thomas Vernier, Jonathan W Said, Martin A Gundersen, H Phillip Koeffler
Publikováno v:
PLoS ONE, Vol 7, Iss 8, p e43891 (2012)
Nanosecond pulsed electric fields (nsPEF) induce apoptotic pathways in human cancer cells. The potential therapeutic effective of nsPEF has been reported in cell lines and in xenograft animal tumor model. The present study investigated the ability of
Externí odkaz:
https://doaj.org/article/b4aae9c2b5254419b1ea48d99254aad2
Autor:
H. Phillip Koeffler, Rocio Alvarez, Yoshio Kuwayama, George Y. Liu, Quoc Ho, Sigal Gery, Milan R. Uskokovic, Niels Borregaard, Tadayuki Akagi, Ryoko Okamoto
Publikováno v:
International Journal of Cancer. 134:207-217
We have synthesized 39 1,25-dihydroxyvitamin D3 [1,25(OH)2D3] analogs having two side chains attached to carbon-20 (Gemini) with various modifications and compared their anticancer activities. Five structure–function rules emerged to identify analo
Autor:
Kentaro Bandobashi, Naoki Komatsu, Tetsuya Kubota, Makoto Kobayashi, Yoshiki Uemura, Yoshio Kuwayama, Hirokuni Taguchi
Publikováno v:
Internal medicine. 46(10):675-678
We describe a 27-year-old man with hypereosinophilc syndrome (HES) presenting acute abdomen due to acute thrombosis of the mesenteric artery, who had a past history of eosinophilic pneumonia followed by multiple arterial thromboses of the extremities
Autor:
H. Phillip Koeffler, Chie Nishioka, Yang Yang, Hirokuni Taguchi, Takayuki Ikezoe, Yoshihiro Adachi, Yoshio Kuwayama, Kentaro Bandobashi, Tamotsu Takeuchi
Publikováno v:
Leukemia research. 31(5):673-682
This study found that phosphatidylinositol 3-kinase (PI3K)/Akt/mammalian target of rapamycin (mTOR) signaling was activated in human T-cell lymphotropic virus type I (HTLV-1)-infected leukemia cells. Rapamycin (1-100 nM, 48h), the inhibitor of mTOR a
Autor:
Ryoko, Okamoto, Sigal, Gery, Yoshio, Kuwayama, Niels, Borregaard, Quoc, Ho, Rocio, Alvarez, Tadayuki, Akagi, George Y, Liu, Milan R, Uskokovic, H Phillip, Koeffler
Publikováno v:
International journal of cancer. 134(1)
We have synthesized 39 1,25-dihydroxyvitamin D3 [1,25(OH)2D3] analogs having two side chains attached to carbon-20 (Gemini) with various modifications and compared their anticancer activities. Five structure-function rules emerged to identify analogs
Autor:
Jack Weissberg, Amanda Leiter, P. Thomas Vernier, Antonie Meixel, Weikai Chen, Martin A. Gundersen, Catherine B. Goff, David Sawcer, Daria Gaut, Yoshio Kuwayama, Wangrong G. Yang, Hongtao Xing, Fikret Nuri Kirkbir, H. Phillip Koeffler, Dong Yin, Jonathan W. Said
Publikováno v:
PloS one, vol 7, iss 8
PLoS ONE, Vol 7, Iss 8, p e43891 (2012)
PLoS ONE
PLoS ONE, Vol 7, Iss 8, p e43891 (2012)
PLoS ONE
Nanosecond pulsed electric fields (nsPEF) induce apoptotic pathways in human cancer cells. The potential therapeutic effective of nsPEF has been reported in cell lines and in xenograft animal tumor model. The present study investigated the ability of
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::989b66c79cabf51bab1a7993fd9168a5
https://escholarship.org/uc/item/291048tk
https://escholarship.org/uc/item/291048tk
Autor:
Chie Nishioka, Takayuki Ikezoe, Taizo Tasaka, Jing Yang, Akihito Yokoyama, Atsushi Miwa, H. Phillip Koeffler, Yoshio Kuwayama, Kazuto Togitani
Ki11502 is a novel multitargeted receptor tyrosine kinase (RTK) inhibitor with selectivity against platelet-derived growth factor receptor alpha/beta (PDGFRα/β). Ki11502 (0.1-1 nM, 2 days) profoundly caused growth arrest, G0/G1 cell-cycle arrest, a
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::373c2f107c429a22d96de5055c9f2d13
https://europepmc.org/articles/PMC2384135/
https://europepmc.org/articles/PMC2384135/
Autor:
Chie Nishioka, Taizo Tasaka, Ayuko Taniguchi, Takayuki Ikezoe, Kazuto Togitani, Jing Yang, Hirokuni Taguchi, Kentaro Bandobashi, Naoki Komatsu, Yoshio Kuwayama, H. Phillip Koeffler
Publikováno v:
Molecular cancer therapeutics. 6(6)
The Aurora kinases play an important role in chromosome alignment, segregation, and cytokinesis during mitosis. Aberrant expression of these kinases occurs in solid tumors and is associated with aneuploidy and carcinogenesis. We found in this study t
Autor:
Kazuto Togitani, Isao Miyoshi, Masanori Daibata, Manabu Matsumoto, Hirokuni Taguchi, Yoshio Kuwayama
Publikováno v:
Internal medicine (Tokyo, Japan). 46(7)
Autor:
Daisuke, Wakao, Nobutaka, Kawai, Yoshio, Kuwayama, Motohiro, Misumi, Yasutaka, Satoh, Tsuneyuki, Shimada, Miki, Akiba, Kuniya, Kishimoto, Katsuhiko, Yoshida, Naoki, Wakimoto, Naoki, Takahashi, Yuichi, Sugahara, Fumiharu, Yagasaki, Yoshihiro, Itoh, Tohru, Sakata, Toshiya, Suzuki, Akira, Matsuda, Masami, Bessho
Publikováno v:
[Rinsho ketsueki] The Japanese journal of clinical hematology. 43(2)
Systemic capillary leak syndrome (SCLS) is a disorder characterized by hypotension, edema, and an increased hematocrit (Ht) due to sudden leakage of plasma into the extravascular space through some unknown mechanism, in which monoclonal gammopathy is