Zobrazeno 1 - 10
of 18
pro vyhledávání: '"Yoshio Kokusenya"'
Publikováno v:
Chemical and Pharmaceutical Bulletin. 46:1388-1392
As a method for estimation of the antioxidative activity of methanol extracts of crude drugs, cyclic voltammograms (CV), 1, 1-diphenyl-2-picrylhydrasyl (DPPH) radical scavenging activities, and electrochemical detection (ECD)-HPLC were investigated.
Publikováno v:
Chemical and Pharmaceutical Bulletin. 45:487-491
An analytical method for determining the contents of 7 nucleic acid bases, 6 ribonucleosides and 5 deoxyribonucleosides in animal crude drugs were established. The contents in free nucleic acid components (the ice-cold extracts) and in total nucleic
Publikováno v:
Digestive Diseases and Sciences. 40:661-667
The present study was designed to examine the relationship between the gastroprotective efficacy of the locally acting antiulcer drug ecabet sodium (ecabet) against ethanol-induced gastric lesions and the amount of the drug bound to the mucosa in com
Autor:
Hideo Nakai, Kazuya Yamasaki, Yoshio Kokusenya, Tadashi Sato, Akio Hashimoto, Takaaki Miyamoto
Publikováno v:
Chemical and Pharmaceutical Bulletin. 43:2195-2199
An analytical method of determining organic acids in animal crude drugs using selective and sensitive postcolumn-pH buffered electroconductivity detection HPLC was established and the organic acid contents in 10 drugs were determined. Nine organic ac
Autor:
Yoshio Kokusenya, Akio Hashimoto, Tadashi Sato, Kazuya Yamasaki, Takaaki Miyamoto, Hideo Nakai
Publikováno v:
YAKUGAKU ZASSHI. 115:62-71
Publikováno v:
Journal of Chromatography A. 672:125-133
Imidapril hydrochloride, a newly synthesized angiotensin-converting enzyme (ACE) inhibitor, is administered as a single enantiomer ( SSS -form) because it is the most active of the eight possible optical isomers. Three different approaches to applyin
Publikováno v:
Journal of Chromatography A. 659:449-457
Chiral separation in capillary zone electrophoresis was investigated employing four kinds of cyclodextrins (CDs). The effects of the type and amount of CDs added to the background electrolyte and the pH of the buffer solution on the resolution of ena
Publikováno v:
Chemical and Pharmaceutical Bulletin. 42:1636-1641
The contents of free amino acids (FAA) and total amino acids (TAA; including peptide and protein forms) in 10 animal drugs were determined using precolumn-derivatization high performance liquid chromatography (HPLC). The results showed that the FAA a
Publikováno v:
BUNSEKI KAGAKU. 41:275-279
酵素反応とHPLC-電気化学検出法とを組み合わせて胃液中のレシチン(ホスファチジルコリン)を高感度に測定する方法を開発した.レシチンは胃液からクロロホルム・メタノール混液(1:1)によ
Publikováno v:
Chemical and Pharmaceutical Bulletin. 48:235-237
In order to clarify the mechanism of action for the antioxidative activity of fluvastatin sodium (FLV, (+/-)-sodium (3RS, 5RS, 6E)-7-[3-(4-fluorophenyl)-1-(1-methylethyl)-1H-indol-2-yl]-3, 5-dihydroxy-6-heptanoate) and its derivatives, reaction of th