Zobrazeno 1 - 10
of 33
pro vyhledávání: '"Yoshio Iwasawa"'
Autor:
Kaori Fukuzawa, Kotoko Nakata, Junwei Zhang, Yuji Mochizuki, Hiroshi Chuman, Yoshio Iwasawa, Masahiro Aizawa, Tatsuya Nakano, Shinji Amari
Publikováno v:
Journal of Chemical Information and Modeling. 46:221-230
We have developed a visualized cluster analysis of protein-ligand interaction (VISCANA) that analyzes the pattern of the interaction of the receptor and ligand on the basis of quantum theory for virtual ligand screening. Kitaura et al. (Chem. Phys. L
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a52307523f9526c4f1b86787d2d5ed24
https://doi.org/10.1021/ci050262q
https://doi.org/10.1021/ci050262q
Publikováno v:
Computational Biology and Chemistry. 28:401-407
KiBank is a database of inhibition constant (K"i) values with 3D structures of target proteins and chemicals. K"i values were accumulated from peer-reviewed literature searched via PubMed. The 3D structure files of target proteins were originally fro
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1498191bc2b4dccd0c39087872385170
https://doi.org/10.1016/j.compbiolchem.2004.09.003
https://doi.org/10.1016/j.compbiolchem.2004.09.003
Autor:
Masahiro Aizawa, Kotoko Nakata, Yoshio Iwasawa, Shinji Amari, Tatsuya Nakano, Kenji Onodera, Junwei Zhang
Publikováno v:
YAKUGAKU ZASSHI. 124:613-619
KiBank is a database for computer-aided drug design and consists of binding affinities and chemical and target protein structures. Each chemical or protein structure with hydrogen atoms added was optimized by energy minimization and stored in PDB or
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::67c8eb0544a63f719b77187fc524cc44
https://doi.org/10.1248/yakushi.124.613
https://doi.org/10.1248/yakushi.124.613
Autor:
Yoshio Iwasawa, Takuma Danjo
Publikováno v:
Folia Pharmacologica Japonica. 117:387-393
Sumatriptan succinate (SMT) was a highly specific 5-HT1-receptor agonist. It showed high affinity only for 5-HT but no affinity for other neurotransmitter receptors such as muscarinic, dopamine D1, D2, adrenergic alpha 1, alpha 2, and beta. Furthermo
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::6ad6244421539d4bc3617318871c9bb2
https://doi.org/10.1254/fpj.117.387
https://doi.org/10.1254/fpj.117.387
Autor:
Masahiro, Aizawa, Kenji, Onodera, Junwei, Zhang, Shinji, Amari, Yoshio, Iwasawa, Tatsuya, Nakano, Kotoko, Nakata
Publikováno v:
Yakugaku zasshi : Journal of the Pharmaceutical Society of Japan. 124(9)
KiBank is a database for computer-aided drug design and consists of binding affinities and chemical and target protein structures. Each chemical or protein structure with hydrogen atoms added was optimized by energy minimization and stored in PDB or
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::56e74bd77aa723b71ae41f379588096c
https://pubmed.ncbi.nlm.nih.gov/15340183
https://pubmed.ncbi.nlm.nih.gov/15340183
Publikováno v:
Japanese Journal of Pharmacology. 82:274
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::eaf9d1ad00c58e0cf08f5689a74626f7
https://doi.org/10.1016/s0021-5198(19)48557-0
https://doi.org/10.1016/s0021-5198(19)48557-0
Publikováno v:
Japanese Journal of Pharmacology. 79:231
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::2b7a7d6e431366925a028a7662cc368b
https://doi.org/10.1016/s0021-5198(19)34938-8
https://doi.org/10.1016/s0021-5198(19)34938-8
Publikováno v:
Japanese Journal of Pharmacology. 76:204
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::08f850e79f76d92d8441522bab3508a1
https://doi.org/10.1016/s0021-5198(19)40925-6
https://doi.org/10.1016/s0021-5198(19)40925-6
Publikováno v:
Japanese Journal of Pharmacology. 76:203
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::2717943516906ea635806560430061b0
https://doi.org/10.1016/s0021-5198(19)40923-2
https://doi.org/10.1016/s0021-5198(19)40923-2
Publikováno v:
Chemical and Pharmaceutical Bulletin. 28:2384-2393
Various dimethyl 3-substituted pyrrole-2, 4-dicarboxylates (3) were synthesized by the reaction of methyl isocyanoacetate (2) with methyl α-isocyanoacrylates (5) in the presence of base. This type of reaction was also applicable to the preparation o
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::8c7ad82f3a7aef813b5b632c9292ddd5
https://doi.org/10.1248/cpb.28.2384
https://doi.org/10.1248/cpb.28.2384