Zobrazeno 1 - 10
of 74
pro vyhledávání: '"Yoshio Akagi"'
Autor:
Akihiro Umezawa, Takashi Yazawa, Yunfeng Ju, Kaoru Miyamoto, Tsutomu Ogata, Yoshio Akagi, Masaru Inatani, Noriyuki Katsumata, Takehiro Matsumura, Maki Fukami, Tetsuya Mizutani, Masafumi Kanno, Tadayuki Ayabe, Yoshitaka Imamichi, Shinya Kawabe
Publikováno v:
The FASEB Journal. 27:3198-3208
Steroidogenic factor 1 (SF-1) is a master regulator for steroidogenesis. In this study, we identified novel SF-1 target genes using a genome-wide promoter tiling array and a DNA microarray. SF-1 was found to regulate human glutathione S-transferase A
Publikováno v:
JAPANESE ORTHOPTIC JOURNAL. 39:239-243
Publikováno v:
Life Sciences. 84:857-864
Aims Hyperglycemia-induced oxidative stress is implicated in pericyte apoptosis seen in diabetic retinopathy. The six mammalian Peroxiredoxins (PRDXs) comprise a novel family of antioxidative proteins that negatively regulate oxidative stress-induced
Publikováno v:
Ophthalmology. 116:1151-1157
Purpose To determine the feasibility and clinical effectiveness of intravitreal bevacizumab combined with cataract surgery for management of the postoperative increase of retinal thickness in patients with diabetic maculopathy. Design Prospective, ra
Publikováno v:
British Journal of Ophthalmology. 93:1081-1084
Peroxiredoxin 6 (Prdx6), a new family of antioxidants, regulates gene expression and function by controlling reactive oxygen species, delays hereditary cataracts in rats and protects epithelial cells in the lens against oxidative stresses.To investig
Publikováno v:
Diabetes Research and Clinical Practice. 82:18-24
Aims A major contributory factor to diabetic cataract formation is increased aldose reductase (AR) activity in the polyol pathway. We investigated the effects of aldose reductase inhibition by RNA interference (RNAi) of the aldose reductase gene and
Publikováno v:
Eye. 22:1442-1445
To elucidate the putative role of human papillomavirus (HPV) infection in pterygium and conjunctival papilloma.Hybrid capture II (HC-II) and polymerase chain reaction (PCR) assays were performed to detect HPV in pterygium (42 samples obtained from 40
Publikováno v:
American Journal of Physiology-Cell Physiology. 294:C842-C855
A diminished level of endogenous antioxidant in cells/tissues is associated with reduced resistance to oxidative stress. Peroxiredoxin 6 (PRDX6), a protective molecule, regulates gene expression/function by controlling reactive oxygen species (ROS) l
Publikováno v:
Experimental Eye Research. 84:246-253
P-glycoprotein (P-gp), a plasma membrane protein, is thought to function in the export of cytotoxic drugs and to act as a modulator of chloride channels that regulate cell volume in many cell types. P-gp has been shown to play a role in lens volume r
Publikováno v:
Experimental Eye Research. 83:865-870
Dogs fed galactose develop diabetes-like ocular complications that include keratopathy, cataracts, and retinopathy. The purpose of this study was to investigate whether galactosemic dogs display reduced aqueous flow similar to that observed in patien