Zobrazeno 1 - 10
of 170
pro vyhledávání: '"Yoshio, Kodera"'
Publikováno v:
Scientific Reports, Vol 14, Iss 1, Pp 1-11 (2024)
Abstract FtsZ is highly conserved among bacteria and plays an essential role in bacterial cell division. The tense conformation of FtsZ bound to GTP assembles into a straight filament via head-to-tail associations, and then the upper subunit of FtsZ
Externí odkaz:
https://doaj.org/article/591cf8474d744504855f1624a743a1ea
Autor:
Mayu Nakagawa, Toshihide Matsumoto, Ako Yokoi, Miki Hashimura, Yasuko Oguri, Ryo Konno, Yu Ishibashi, Takashi Ito, Kensuke Ohhigata, Yohei Harada, Naomi Fukagawa, Yoshio Kodera, Makoto Saegusa
Publikováno v:
Molecular Oncology, Vol 17, Iss 10, Pp 2168-2182 (2023)
Ezrin‐radixin‐moesin‐binding phosphoprotein 50 (EBP50) is a scaffold protein that is required for epithelial polarity. Knockout (KO) of membranous EBP50 (Me‐EBP50) in ovarian clear cell carcinoma (OCCC) cells induced an epithelial–mesenchym
Externí odkaz:
https://doaj.org/article/7e7954c3079048c69b5d73cd08649fda
Autor:
Maho Tsuchiya, Yoshihisa Ohashi, Kensuke Fukushima, Yusei Okuda, Arisa Suto, Takashi Matsui, Yoshio Kodera, Masashi Sato, Ayumi Tsukada, Gen Inoue, Masashi Takaso, Kentaro Uchida
Publikováno v:
International Journal of Molecular Sciences, Vol 25, Iss 7, p 4085 (2024)
Osteoarthritis (OA) is a prevalent degenerative joint disorder characterized by cartilage erosion, structural changes, and inflammation. Synovial fibroblasts play a crucial role in OA pathophysiology, with abnormal fibroblastic cells contributing sig
Externí odkaz:
https://doaj.org/article/053c5555dbbe4d68a4bbd386227d903a
Autor:
Hiromi Watari, Hiromu Kageyama, Nami Masubuchi, Hiroya Nakajima, Kako Onodera, Pamela J. Focia, Takumi Oshiro, Takashi Matsui, Yoshio Kodera, Tomohisa Ogawa, Takeshi Yokoyama, Makoto Hirayama, Kanji Hori, Douglas M. Freymann, Misa Imai, Norio Komatsu, Marito Araki, Yoshikazu Tanaka, Ryuichi Sakai
Publikováno v:
Nature Communications, Vol 13, Iss 1, Pp 1-11 (2022)
The mode of cytokine receptor activation is diverse. Here, the authors find that the marine-sponge derived lectin ThC, a bivalent sugar binding protein, activates human cytokine receptor MPL. This mode of action resembles the pathogenic activation of
Externí odkaz:
https://doaj.org/article/738b2a8a80c14fc9844ae3c420641088
Autor:
Toshiya Sato, Kanako Oda, Seiko Sakai, Rika Kato, Saori Yamamori, Makoto Itakura, Yoshio Kodera, Masatoyo Nishizawa, Toshikuni Sasaoka, Osamu Onodera, Minesuke Yokoyama
Publikováno v:
Scientific Reports, Vol 12, Iss 1, Pp 1-9 (2022)
Abstract TAR DNA-binding protein 43 kDa (TDP-43), a nuclear protein, plays an important role in the molecular pathogenesis of amyotrophic lateral sclerosis (ALS). The long-disordered C-terminal region (CTR) of TDP-43 is known to be aggregation-prone
Externí odkaz:
https://doaj.org/article/419759e22ee04f0e92a2be83c4e71e34
Autor:
Maho Tsuchiya, Yoshihisa Ohashi, Yoshio Kodera, Masashi Satoh, Takashi Matsui, Kensuke Fukushima, Dai Iwase, Jun Aikawa, Manabu Mukai, Gen Inoue, Masashi Takaso, Kentaro Uchida
Publikováno v:
Biomedicines, Vol 11, Iss 11, p 3047 (2023)
Recent studies utilizing single-cell analysis have unveiled the presence of various fibroblast (Fb) subsets within the synovium under inflammatory conditions in osteoarthritis (OA), distinguishing them from those in rheumatoid arthritis (RA). Moreove
Externí odkaz:
https://doaj.org/article/14985672141845a4bcea60fb6cc3694a
Publikováno v:
Scientific Reports, Vol 11, Iss 1, Pp 1-9 (2021)
Abstract Recent mass spectrometry (MS)-based techniques enable deep proteome coverage with relative quantitative analysis, resulting in increased identification of very weak signals accompanied by increased data size of liquid chromatography (LC)–M
Externí odkaz:
https://doaj.org/article/c4b961b0216b4cf98d42bebbb6cc47ec
Autor:
Yoichi Sekita, Yuki Sugiura, Akari Matsumoto, Yuki Kawasaki, Kazuya Akasaka, Ryo Konno, Momoka Shimizu, Toshiaki Ito, Eiji Sugiyama, Terushi Yamazaki, Eriko Kanai, Toshinobu Nakamura, Makoto Suematsu, Fumitoshi Ishino, Yoshio Kodera, Takashi Kohda, Tohru Kimura
Publikováno v:
Stem Cell Research & Therapy, Vol 12, Iss 1, Pp 1-15 (2021)
Abstract Background Phosphoinositide-3 kinase (PI3K)/AKT signaling participates in cellular proliferation, survival and tumorigenesis. The activation of AKT signaling promotes the cellular reprogramming including generation of induced pluripotent ste
Externí odkaz:
https://doaj.org/article/305914cc50854a9697a903f692dbfafd
Autor:
Tsuguto Masaki, Yoshio Kodera, Michishige Terasaki, Kazumi Fujimoto, Tsutomu Hirano, Masayoshi Shichiri
Publikováno v:
Scientific Reports, Vol 11, Iss 1, Pp 1-14 (2021)
Abstract We recently established a new plasma peptidomic technique and comprehensively identified a large number of low-molecular weight and low-abundance native peptides using a single drop of human plasma. To discover a novel polypeptide that poten
Externí odkaz:
https://doaj.org/article/82b71081798b42109aeddb00f459df30
Autor:
Tomomi Taguchi, Yoshio Kodera, Kazuhito Oba, Tatsuya Saito, Yuzuru Nakagawa, Yusuke Kawashima, Masayoshi Shichiri
Publikováno v:
Scientific Reports, Vol 11, Iss 1, Pp 1-17 (2021)
Abstract Identification of low-abundance, low-molecular-weight native peptides using non-tryptic plasma has long remained an unmet challenge, leaving potential bioactive/biomarker peptides undiscovered. We have succeeded in efficiently removing high-
Externí odkaz:
https://doaj.org/article/cdc5cf7e975746e1bf9c6d7737b91281