Zobrazeno 1 - 10
of 679
pro vyhledávání: '"Yoshinori Tanaka"'
Publikováno v:
Autophagy Reports, Vol 3, Iss 1 (2024)
ABSTRACTThe pathological accumulation of the nuclear protein TDP-43 (TAR DNA-binding protein 43 kDa) in the cytoplasm is characteristic of amyotrophic lateral sclerosis (ALS) and frontotemporal lobar degeneration (FTLD-TDP), and its spread through th
Externí odkaz:
https://doaj.org/article/498b64eb164e400e8bdb8158f490f590
Publikováno v:
Biochemistry and Biophysics Reports, Vol 38, Iss , Pp 101705- (2024)
(Macro)autophagy is a cellular degradation system for unnecessary materials, such as aggregate-prone TDP-43, a central molecule in neurodegenerative diseases including amyotrophic lateral sclerosis and frontotemporal lobar degeneration. Abemaciclib (
Externí odkaz:
https://doaj.org/article/6e41ffab52e64792978198969ecabe96
Autor:
Takao Watanabe, Yoshio Tokumoto, Kouji Joko, Kojiro Michitaka, Norio Horiike, Yoshinori Tanaka, Atsushi Hiraoka, Fujimasa Tada, Hironori Ochi, Yoshiyasu Kisaka, Seiji Nakanishi, Sen Yagi, Kazuhiko Yamauchi, Makoto Higashino, Kana Hirooka, Makoto Morita, Yuki Okazaki, Atsushi Yukimoto, Masashi Hirooka, Masanori Abe, Yoichi Hiasa
Publikováno v:
Scientific Reports, Vol 13, Iss 1, Pp 1-12 (2023)
Abstract The time point of the most precise predictor of hepatocellular carcinoma (HCC) development after viral eradication with direct-acting antiviral (DAA) therapy is unclear. In this study we developed a scoring system that can accurately predict
Externí odkaz:
https://doaj.org/article/02e928ce943d4b889b09d5ae76d10745
Publikováno v:
Journal of Medical Case Reports, Vol 17, Iss 1, Pp 1-7 (2023)
Abstract Background Patients with Hodgkin lymphoma exhibit various clinical presentations. Needle biopsy of the lymph nodes is a minimally invasive procedure and a useful diagnostic method for malignant lymphomas. However, at times it is difficult to
Externí odkaz:
https://doaj.org/article/2f078cdca7d34de09dd78e36ca38bd5c
Autor:
Jason A. Kirkbride, Garbo Young Nilsson, Jee In Kim, Kosuke Takeya, Yoshinori Tanaka, Hiroshi Tokumitsu, Futoshi Suizu, Masumi Eto
Publikováno v:
Biomolecules, Vol 13, Iss 12, p 1741 (2023)
Raf-1, a multifunctional kinase, regulates various cellular processes, including cell proliferation, apoptosis, and migration, by phosphorylating MAPK/ERK kinase and interacting with specific kinases. Cellular Raf-1 activity is intricately regulated
Externí odkaz:
https://doaj.org/article/7f16d453ccd64bd48185e76736845ef4
Autor:
Masato Maekawa, Terumi Taniguchi, Kazuto Nishio, Kazuko Sakai, Kazuyuki Matsushita, Kaname Nakatani, Takayuki Ishige, Makoto Ikejiri, Hiroshi Nishihara, Kuniko Sunami, Yasushi Yatabe, Kanako C. Hatanaka, Yutaka Hatanaka, Yoshihiro Yamamoto, Keita Fukuyama, Shinya Oda, Kayoko Saito, Mamoru Yokomura, Yuji Kubo, Hiroko Sato, Yoshinori Tanaka, Misa Fuchioka, Tadashi Yamasaki, Koichiro Matsuda, Kiyotaka Kurachi, Kazuhiro Funai, Satoshi Baba, Moriya Iwaizumi
Publikováno v:
Scientific Reports, Vol 12, Iss 1, Pp 1-7 (2022)
Abstract To implement precision oncology, analytical validity as well as clinical validity and utility are important. However, proficiency testing (PT) to assess validity has not yet been systematically performed in Japan. To investigate the quality
Externí odkaz:
https://doaj.org/article/7c2d199b86fd4cf6a1076280fcb3d386
Publikováno v:
Current Research in Physiology, Vol 5, Iss , Pp 389-398 (2022)
Purpose: This study investigated the effects of 1400 mL intake of alkaline electrolyzed water (AEW) or purified water (PW) into which carbohydrate-electrolyte (CE) was dissolved on improving physiological responses during exercise under heat stress.
Externí odkaz:
https://doaj.org/article/71d5a5758a60436c8daadc7b809ed2a0
Autor:
Yoshinori Tanaka, Kenji Kikuchi
Publikováno v:
Results in Chemistry, Vol 5, Iss , Pp 100984- (2023)
In our basic study that used a low water flow rate of 100 ml/min, the amount of dissolved hydrogen produced during water electrolysis varied according to the roughness factor of the electrode, which is thought to affect the state of supersaturation a
Externí odkaz:
https://doaj.org/article/a7a109799c5742fab18d2bf03bcb3dd0
Autor:
Takao Watanabe, Yoshio Tokumoto, Kouji Joko, Kojiro Michitaka, Norio Horiike, Yoshinori Tanaka, Fujimasa Tada, Yoshiyasu Kisaka, Seiji Nakanishi, Kazuhiko Yamauchi, Hironori Ochi, Atsushi Hiraoka, Sen Yagi, Atsushi Yukimoto, Masashi Hirooka, Masanori Abe, Yoichi Hiasa
Publikováno v:
BMC Cancer, Vol 21, Iss 1, Pp 1-12 (2021)
Abstract Background An unexpected recurrence of hepatocellular carcinoma (HCC) sometimes occurs in patients with hepatitis C virus (HCV) after treatment with direct-acting antivirals (DAAs). However, the characteristics of patients with HCC recurrenc
Externí odkaz:
https://doaj.org/article/b950ecc9ef464953a9212454de78a5f6
Autor:
Hiroshi Akatsuka, Yoshinori Tanaka
Publikováno v:
Entropy, Vol 25, Iss 2, p 276 (2023)
Electron temperature is reconsidered for weakly-ionized oxygen and nitrogen plasmas with its discharge pressure of a few hundred Pa, with its electron density of the order of 1017m−3 and in a state of non-equilibrium, based on thermodynamics and st
Externí odkaz:
https://doaj.org/article/37d2a349573f47eb9f5ca37f5d7ccf28