Zobrazeno 1 - 10
of 24
pro vyhledávání: '"Yoshinori TAMURA"'
Autor:
Masanori HORIE, Hironaga AKITA, Yusuke NAKAMICHI, Kazuhiro NARA, Tatsuhiro TAKAYAMA, Yoshinori TAMURA
Publikováno v:
Japan Journal of Food Engineering. 23:87-94
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::c446031c6440910fe72daa1d3f9855ee
https://doi.org/10.11301/jsfe.22609
https://doi.org/10.11301/jsfe.22609
Autor:
Shin-Ichiro Hara, Yoshinori Tamura, Shuuichi Oonishi, Yoshihisa Goto, Masanao Inagaki, Nobuhiro Haga, Hiroyuki Kai, Katsumi Koike, Tsuyoshi Hasegawa, Takashi Nakamura, Masaharu Kume, Toshiyuki Kanemasa
Publikováno v:
Bioorganic & Medicinal Chemistry Letters. 29:73-77
Structure-activity relationship studies of several morphinan derivatives were conducted to obtain dual antagonists for μ- and δ-opioid receptors. We discovered peripherally restricted dual antagonists for μ/δ-opioid receptors as a new chemotype w
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::9c26b52203a2e18c5ba1611affa36e56
https://doi.org/10.1016/j.bmcl.2018.11.007
https://doi.org/10.1016/j.bmcl.2018.11.007
Autor:
Yoshiyuki, Taoda, Toshiyuki, Akiyama, Kenji, Tomita, Misato, Fujiwara-Kitamura, Yoshinori, Tamura, Takashi, Kawasuji, Eriko, Matsuoka, Erika, Akihisa, Takahiro, Seki, Tomokazu, Yoshinaga
Publikováno v:
Bioorganic & Medicinal Chemistry Letters. 64:128664
We have been conducting exploratory research to develop human immunodeficiency virus type-1 (HIV-1) integrase-LEDGF/p75 allosteric inhibitors (INLAIs). Here, we report on a newly designed compound with a tricyclic scaffold that shows promise as an in
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::af709c6d042ce7be9bddb8102fc01bd8
https://doi.org/10.1016/j.bmcl.2022.128664
https://doi.org/10.1016/j.bmcl.2022.128664
Publikováno v:
Nishi Nihon Hifuka. 64:606-611
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::5b940e4f1dd4dfbc978200ef90fd00cf
https://doi.org/10.2336/nishinihonhifu.64.606
https://doi.org/10.2336/nishinihonhifu.64.606
Autor:
Yoshinori Tamura, Mitsuaki Yodo, Tsuzuki Hiroshige, Fumihiko Watanabe, Mitsuaki Ohtani, Ryuichi Kiyama
Publikováno v:
Journal of Medicinal Chemistry. 42:1723-1738
Three-dimensional models for the catalytic domain of gelatinases (MMP-9 and -2) have been constructed based on the X-ray crystal structure of MMP-3. Conformations of the loop segment which forms the bottom half of the S1' subsite but shows conformati
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::7fdde0dab09c28a5966a89000090fae4
https://doi.org/10.1021/jm980514x
https://doi.org/10.1021/jm980514x
Autor:
Takuji Nakatani, Tadafumi Komurasaki, Mitsuaki Ohtani, Yoshinori Tamura, Kenji Kawada, Masanao Inagaki, Tatsuo Tsuri, Nobuhiro Haga, Masahiro Fuji, Shuji Yonezawa, Shozo Takechi, Akira Kugimiya, Teruhiko Taishi, Susumu Mitsumori
Publikováno v:
The Journal of Organic Chemistry. 63:5831-5837
We achieved a total synthesis of terprenin, a novel potent immunoglobulin E antibody suppressant which was obtained from the fermentation broth of Aspergillus candidus RF-5672 and has a highly oxygenated p-terphenyl skeleton with a prenyloxy side cha
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::510b301d97175cec1ef1586ae258642a
https://doi.org/10.1021/jo980349t
https://doi.org/10.1021/jo980349t
Autor:
Yozo Hori, Kenji Kawada, Yoshitsugu Kokuryo, Akira Kugimiya, Yoshinori Tamura, Takuji Nakatani, Ryuji Suzuki, Kyozo Kawata, Mitsuaki Ohtani, Kenji Kuwabara, Mitsunobu Matsumoto
Publikováno v:
Journal of Medicinal Chemistry. 40:3280-3291
An ongoing search for new antifolate drugs useful against rheumatoid arthritis (RA) led us to prepare new methotrexate (MTX) derivatives containing enantiomerically pure L-erythro- or L-threo-gamma-fluoroglutamic acid. The derivatives in which the ph
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::cdd30acfde9bf845e8d095a0a99fe621
https://doi.org/10.1021/jm970085n
https://doi.org/10.1021/jm970085n
Autor:
Miyuki Kagawa, Takuma Sasaki, Kaori Yamasaki, Yoshinori Tamura, Fumio Yoneda, Ken-ichi Sugita, Tetsutaro Kimachi
Publikováno v:
Bioorganic & Medicinal Chemistry Letters. 7:753-756
A series of 5-deazaflavo-10,11-quinones having o-quinone structure in the molecule were synthesized. The cytotoxicity of 5-deazaflavo-6,9-quinones (p-quinone derivatives) and 5-deazaflavo-10,11-quinones (o-quinones) was evaluated in vitro against L12
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::8384d8f89d6640aa38ffbd505c7cf861
https://doi.org/10.1016/s0960-894x(97)00100-5
https://doi.org/10.1016/s0960-894x(97)00100-5
Autor:
Takuji Nakatani, Mitsuaki Ohtani, Yoshinori Tamura, Kobee Kobayashi, Yoshitsugu Kokuryo, Kenji Kawada
Publikováno v:
Tetrahedron: Asymmetry. 7:3545-3551
Enantiomerically pure L- erythro - and L- threo -4-fluoroglutamic acids 1a and 1b were conveniently prepared. The key steps in this synthesis relied upon separation of diastereomers of N -chloroacetyl-4-fluoroglutamic acid 5-methyl ester 7 by recryst
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::20be1b97a11adc270edc09ddc17c465a
https://doi.org/10.1016/s0957-4166(96)00462-4
https://doi.org/10.1016/s0957-4166(96)00462-4
Autor:
Kenji Kawada, Takuji Nakatani, Ryuji Suzuki, Ken Yasui, Mitsuaki Ohtani, Yoshinori Tamura, Kenzo Koizumi, Isao Horibe
Publikováno v:
The Journal of Antibiotics. 49:173-180
5beta-Methoxy (20), 14-methyl (24), 14,14-dibromo-15-nor (25), 8-O-acyl (26-45), 8-O-alkyl (46), 8-O-alkoxycarbonyl (47, 48), and 8-O-carbamoyl (49) derivatives of PA-48153C, a novel immunosuppressant isolated from fermentation products of Streptomyc
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d8090d622eff76808862f986e2633b99
https://doi.org/10.7164/antibiotics.49.173
https://doi.org/10.7164/antibiotics.49.173