Zobrazeno 1 - 10
of 26
pro vyhledávání: '"Yoshinori Nakae"'
Autor:
Ken Hachimine, Masahide Kuroki, Yoshinori Nakae, Motomu Kuroki, Isao Sakata, Hirotomo Shibaguchi, Tetsushi Kinugasa, Yuichi Yamashita, Takayuki Shirakusa, Ryuji Asano, Hiromi Yamada
Publikováno v:
Cancer Science. 98:916-920
To improve the efficacy of sonodynamic therapy of cancer using photosensitizers, we developed a novel porphyrin derivative designated DCPH-P-Na(I) and investigated its photochemical characteristics and sonotoxicity on tumor cells. DCPH-P-Na(I) exhibi
Autor:
Yoshinori Nakae, Itaru Yamamoto, Akihiro Tai, Jun Takebayashi, Ryuji Asano, Eiichi Gohda, Morio Saito
Publikováno v:
Bioscience, Biotechnology, and Biochemistry. 71:754-760
The 1,1-diphenyl-2-picrylhydrazyl (DPPH) radical-scavenging mechanism of 2-O-alpha-D-glucopyranosyl-L-ascorbic acid (AA-2G) was studied. We found two undefined products, named X and Y, in the reaction mixture of AA-2G and the DPPH radical under acidi
Autor:
Eiichiro Fukusaki, Akio Kobayashi, Yoshinori Nakae, Isao Sakata, Susumu Nakajima, Shin'ichiro Kajiyama
Publikováno v:
Journal of Photochemistry and Photobiology A: Chemistry. 174:187-193
New chlorin derivatives were synthesized from protoporphyrin IX dimethyl ester ( 1 ) as a starting material. The tumor-localizing abilities were determined by bathochromic and hyperchromic shift test using albumin and the photosensitivities were eval
Autor:
Yoshinori Nakae, Isao Sakata, Shin'ichiro Kajiyama, Eiichiro Fukusaki, Akio Kobayashi, Susumu Nakajima
Publikováno v:
Journal of Photochemistry and Photobiology A: Chemistry. 172:55-61
Eleven Ga-phorphyrin complexes bearing various lengths of carbon-chain were synthesized and the UV–vis spectra shift patterns in various concentrations of albumin solutions were evaluated. The distributions of these derivatives into the organs were
Publikováno v:
Journal of Photochemistry and Photobiology A: Chemistry. 171:91-95
Two kinds of convenient photosensitivity screening methods (Methods A and B) were established to find new photosensitizers for photodynamic therapy (PDT). Method A is based on oxidation mechanism of cholesterol and types I and II can be specified. Me
Publikováno v:
Electroanalysis. 12:1282-1285
Gallium(III) tetraphenylporphyrin (GaTPP) was found to act as an ionophore for valproate, an agent widely used for anti-epileptic therapy. An electrode constructed using GaTPP and bis(1-butylpentyl)decane-1,10-diyl diglutarate (ETH 469) as a membrane
Autor:
Susumu Nakajima, Hidetoshi Takahashi, Hajime Iizuka, Ryuji Asano, Yoshinori Nakae, Isao Sakata
Publikováno v:
Journal of Dermatological Science. 55:130-132
Autor:
Hajime Iizuka, Ryuji Asano, Yoshinori Nakae, Susumu Nakajima, Hidetoshi Takahashi, Isao Sakata
Publikováno v:
Journal of dermatological science. 66(3)
Background Although topical photodynamic therapy (PDT) using 5-aminolevulinic acid (ALA) is applied for skin tumors including actinic keratosis, Bowen disease, and squamous cell carcinoma, there are no approved photosensitizers in dermatological fiel
Publikováno v:
Clinical orthopaedics and related research. 466(7)
Photodynamic therapy (PDT) is an effective cancer treatment modality that allows selective destruction of malignant tumor cells. We asked whether PDT could inhibit in vivo and in vitro growth of synovial sarcoma cells. We analyzed PDT using ATX-S10.N
Autor:
Takeshi Takemura, Noboru Murakami, Isao Sakata, Yoshinori Nakae, Tamio Aburano, Takashi Fujii, Susumu Nakajima
Publikováno v:
Cancer letters. 181(2)
A tumor localizing radiation sensitizer, KADT-F10, in which two molecules of nitroimidazole fluorinate, KU2280, are bound to side chain residues of a tumor localizing Mn–porphyrin was synthesized and evaluated. Suppression of tumor growth was signi