Výsledky vyhledávání - "Yoshinori Maeda"

Culture in 10% O2 enhances the production of active hormones in neuro-endocrine cells by up-regulating the expression of processing enzymes

Autor: Yoshinori Maeda, Daisuke Koga, Masahiro Hosaka, Hiroshi Gomi, Airi Hinata, Yui Sato, Seiji Torii, Tsuyoshi Watanabe, Eri Sato

Publikováno v: Biochemical Journal. 476:827-842

To closely mimic physiological conditions, low oxygen cultures have been employed in stem cell and cancer research. Although in vivo oxygen concentrations in tissues are often much lower than ambient 21% O2 (ranging from 3.6 to 12.8% O2), most cell c

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::a8f3d40438c20e8b624db3a00e53c439
https://doi.org/10.1042/bcj20180832

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Adsolubilization-induced structural change in adsorbed surfactant aggregates: Equilibrium and kinetics monitored by AFM and QCM-D

Autor: Shinya Sasaki, Keito Koizumi, Kenichi Sakai, Yoshinori Maeda, Hideki Sakai, Takeshi Endo, Masahiko Abe

Publikováno v: Colloids and Surfaces A: Physicochemical and Engineering Aspects. 520:231-238

Organic solutes with low water-solubility are solubilized into surfactant aggregates formed at solid/aqueous solution interfaces by the process of adsolubilization. In this study, we have characterized the adsolubilization of 1-hexanol (C6OH) into he

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::b2fdfb6a9d419062d7d56b731f3fe80f
https://doi.org/10.1016/j.colsurfa.2017.01.078

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Calcium phosphate-based organic–inorganic hybrid nanocarriers with pH-responsive on/off switch for photodynamic therapy

Autor: Yoshinori Maeda, Yuji Morimoto, Shigeto Fukushima, Nobuhiro Nishiyama, Kozo Miyazaki, Akihiro Kishimura, Kazuko Toh, Aki Inoue, Kazunori Kataoka, Takahiro Nomoto, Michiaki Kumagai, Yu Matsumoto, Peng Mi

Publikováno v: Biomaterials Science. 4:826-838

Photodynamic therapy (PDT) is a promising treatment modality for malignant tumors in a light-selective manner. To improve the PDT efficacy, numerous kinds of nanocarriers have been developed to deliver photosensitizers (PSs) selectively into the tumo

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::43bb50bac825412f299aed423b5f9190
https://doi.org/10.1039/c6bm00011h

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Culture in 10% O

Autor: Eri, Sato, Yoshinori, Maeda, Yui, Sato, Airi, Hinata, Hiroshi, Gomi, Daisuke, Koga, Seiji, Torii, Tsuyoshi, Watanabe, Masahiro, Hosaka

Publikováno v: The Biochemical journal. 476(5)

To closely mimic physiological conditions, low oxygen cultures have been employed in stem cell and cancer research. Although

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=pmid________::4f0638370e7380f2fb20491662cf52f1
https://pubmed.ncbi.nlm.nih.gov/30787050

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siRNA-Loaded Polyion Complex Micelle Decorated with Charge-Conversional Polymer Tuned to Undergo Stepwise Response to Intra-Tumoral and Intra-Endosomal pHs for Exerting Enhanced RNAi Efficacy

Autor: Yoshinori Maeda, Kanjiro Miyata, Nobuhiro Nishiyama, Hyun Jin Kim, Mitsuru Naito, Ryota Azuma, Jooyeon Ahn, Montira Tangsangasaksri, Kazunori Kataoka, Hiroyasu Takemoto, Daiki Sueyoshi, Yutaka Miura

Publikováno v: Biomacromolecules. 17:246-255

Small interfering RNA (siRNA) needs an efficient delivery vehicle to reach the cytoplasm of target cells for successful RNA interference (RNAi) therapy. This study aimed to develop an siRNA-loaded polyion complex (PIC) micelle equipped with a smart p

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::49bdad77cd829c13ee84d2dbf4445032
https://doi.org/10.1021/acs.biomac.5b01334

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Impaired Processing of Prohormones in Secretogranin III-Null Mice Causes Maladaptation to an Inadequate Diet and Stress

Autor: Yoshinori Maeda, Eri Sato, Daisuke Koga, Masahiro Hosaka, Aika Kayamori, Hiroki Bochimoto, Seiji Torii, Chisato Kubota, Ken Tsushima, Saki Kudo, Hiroshi Gomi, Tsuyoshi Watanabe

Publikováno v: Endocrinology. 159(2)

Secretogranin III (SgIII), a member of the granin family, binds both to another granin, chromogranin A (CgA), and to a cholesterol-rich membrane that is destined for secretory granules (SGs). The knockdown of SgIII in adrenocorticotropic hormone (ACT

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b8a28713a31610e494e3ce5ba6fcb394
https://pubmed.ncbi.nlm.nih.gov/29281094

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Fine-Tuning of Charge-Conversion Polymer Structure for Efficient Endosomal Escape of siRNA-Loaded Calcium Phosphate Hybrid Micelles

Autor: Hiroyasu Takemoto, Nobuhiro Nishiyama, Frederico Pittella, Kazunori Kataoka, Kanjiro Miyata, Yoshinori Maeda, Takahiro Nomoto

Publikováno v: Macromolecular Rapid Communications. 35:1211-1215

For efficient delivery of siRNA into the cytoplasm, a smart block copolymer of poly(ethylene glycol) and charge-conversion polymer (PEG-CCP) is developed by introducing 2-propionic-3-methylmaleic (PMM) amide as an anionic protective group into side c

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::188cbadb7934e1a3b48b6c00e066c631
https://doi.org/10.1002/marc.201400049

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Precise Engineering of siRNA Delivery Vehicles to Tumors Using Polyion Complexes and Gold Nanoparticles

Autor: Kazuko Toh, Frederico Pittella, Hiroyasu Takemoto, Yoshinori Maeda, R. James Christie, Kazunori Kataoka, Kanjiro Miyata, Hiroyuki Chaya, Kotaro Hayashi, Nobuhiro Nishiyama, Yu Yi, Peng Mi, Yu Matsumoto, Hyun Jin Kim, Meng Zheng

Publikováno v: Acs Nano. 8(No. 9):8979-8991

For systemic delivery of siRNA to solid tumors, a size-regulated and reversibly stabilized nanoarchitecture was constructed by using a 20 kDa siRNA-loaded unimer polyion complex (uPIC) and 20 nm gold nanoparticle (AuNP). The uPIC was selectively prep

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::8ca8f5838a12fc488e97bbb25952c6d2
http://t2r2.star.titech.ac.jp/cgi-bin/publicationinfo.cgi?q_publication_content_number=CTT100720784

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