Zobrazeno 1 - 10
of 42
pro vyhledávání: '"Yoshinori Katsuragi"'
Autor:
Kanako Watanabe, Tomoichiro Oka, Hirotaka Takagi, Sergei Anisimov, Shun-ichi Yamashita, Yoshinori Katsuragi, Masahiko Takahashi, Masaya Higuchi, Tomotake Kanki, Akihiko Saitoh, Masahiro Fujii
Publikováno v:
Nature Communications, Vol 14, Iss 1, Pp 1-14 (2023)
Human parechovirus genotype A3 (PeV-A3) can cause severe diseases in neonates and young infants. Here, Watanabe et al. identify a host factor myeloid-associated differentiation marker (MYADM) as essential for PeV-A infection and provide evidence for
Externí odkaz:
https://doaj.org/article/cd09301943444c518db54f125edaa8d5
Autor:
Taichi Kakihana, Masahiko Takahashi, Yoshinori Katsuragi, Shun-Ichi Yamashita, Junya Sango, Tomotake Kanki, Osamu Onodera, Masahiro Fujii
Publikováno v:
iScience, Vol 24, Iss 7, Pp 102733- (2021)
Summary: Amyotrophic lateral sclerosis (ALS) is a degenerative motor neuron disease characterized by the formation of cytoplasmic ubiquitinated TDP-43 protein aggregates in motor neurons. Stress granules (SGs) are stress-induced cytoplasmic protein a
Externí odkaz:
https://doaj.org/article/bb0d48142e314cc6b5490bcc748c29c6
Autor:
Masahiko Takahashi, Hiroki Kitaura, Akiyoshi Kakita, Taichi Kakihana, Yoshinori Katsuragi, Masaaki Nameta, Lu Zhang, Yuriko Iwakura, Hiroyuki Nawa, Masaya Higuchi, Masaaki Komatsu, Masahiro Fujii
Publikováno v:
iScience, Vol 9, Iss , Pp 433-450 (2018)
Summary: Accumulation of ubiquitinated proteins is cytotoxic, but cells inactivate these cytotoxicities by inducing aggresome formation. We found that ubiquitin-specific protease 10 (USP10) inhibits ubiquitinated protein-induced apoptosis by inducing
Externí odkaz:
https://doaj.org/article/7a41ac721654454691e86a1d3bb89a40
Autor:
Satoshi Kojo, Hirokazu Tanaka, Takaho A. Endo, Sawako Muroi, Ye Liu, Wooseok Seo, Mari Tenno, Kiyokazu Kakugawa, Yoshinori Naoe, Krutula Nair, Kazuyo Moro, Yoshinori Katsuragi, Akinori Kanai, Toshiya Inaba, Takeshi Egawa, Byrappa Venkatesh, Aki Minoda, Ryo Kominami, Ichiro Taniuchi
Publikováno v:
Nature Communications, Vol 8, Iss 1, Pp 1-14 (2017)
CD4 and CD8 T cells develop in the thymus with their transcription programs controlled by ThPOK and Runx3, respectively. Here the authors show that a pre-commitment event modulated by the transcription factor, Bcl11b, is required for the proper expre
Externí odkaz:
https://doaj.org/article/0177c41482984628992633de17614903
Autor:
Kazuhiro Okumura, Megumi Saito, Eriko Isogai, Yoshimasa Aoto, Tsuyoshi Hachiya, Yasubumi Sakakibara, Yoshinori Katsuragi, Satoshi Hirose, Ryo Kominami, Ryo Goitsuka, Takuro Nakamura, Yuichi Wakabayashi
Publikováno v:
PLoS ONE, Vol 9, Iss 7, p e102111 (2014)
Previous studies have shown that Meis1 plays an important role in blood development and vascular homeostasis, and can induce blood cancers, such as leukemia. However, its role in epithelia remains largely unknown. Here, we uncover two roles for Meis1
Externí odkaz:
https://doaj.org/article/1ee8ffa80179424789347212c892310d
Autor:
Masahiko Takahashi, Hiroki Kitaura, Akiyoshi Kakita, Taichi Kakihana, Yoshinori Katsuragi, Osamu Onodera, Yuriko Iwakura, Hiroyuki Nawa, Masaaki Komatsu, Masahiro Fujii
Publikováno v:
Mol Cell Biol
TAR DNA-binding protein 43 (TDP-43) is a causative factor of amyotrophic lateral sclerosis (ALS). Cytoplasmic TDP-43 aggregates in neurons are a hallmark pathology of ALS. Under various stress conditions, TDP-43 localizes sequentially to two cytoplas
Autor:
Junya Sango, Yoshinori Katsuragi, Tomotake Kanki, Masahiro Fujii, Shun-ichi Yamashita, Masahiko Takahashi, Taichi Kakihana, Osamu Onodera
Publikováno v:
iScience, Vol 24, Iss 7, Pp 102733-(2021)
iScience
iScience
Summary Amyotrophic lateral sclerosis (ALS) is a degenerative motor neuron disease characterized by the formation of cytoplasmic ubiquitinated TDP-43 protein aggregates in motor neurons. Stress granules (SGs) are stress-induced cytoplasmic protein ag
Autor:
Hiroki Kitaura, Yoshinori Katsuragi, Masahiko Takahashi, Akiyoshi Kakita, Masahiro Fujii, Taichi Kakihana, Sergei Anisimov, Lu Zhang
Publikováno v:
Scientific Reports, Vol 9, Iss 1, Pp 1-16 (2019)
Scientific Reports
Scientific Reports
The aberrant accumulation of ubiquitinated protein aggregates in cells plays a critical role in the pathogenesis of several degenerative diseases, including Parkinson disease (PD) and cystic fibrosis (CF). In this study, we found that Ras GTPase-acti
Autor:
Lu Zhang, Masaaki Nameta, Yoshinori Katsuragi, Masaya Higuchi, Hiroki Kitaura, Masahiko Takahashi, Hiroyuki Nawa, Taichi Kakihana, Yuriko Iwakura, Akiyoshi Kakita, Masahiro Fujii, Masaaki Komatsu
Publikováno v:
iScience
iScience, Vol 9, Iss, Pp 433-450 (2018)
iScience, Vol 9, Iss, Pp 433-450 (2018)
Summary Accumulation of ubiquitinated proteins is cytotoxic, but cells inactivate these cytotoxicities by inducing aggresome formation. We found that ubiquitin-specific protease 10 (USP10) inhibits ubiquitinated protein-induced apoptosis by inducing
Autor:
Masaaki Komatsu, Junya Sango, Masahiko Takahashi, Sergei Anisimov, Yoshinori Katsuragi, Masahiro Fujii, Taichi Kakihana
Publikováno v:
The Journal of Biological Chemistry
Nrf2 is an antioxidant transcriptional activator in many types of cells, and its dysfunction plays key roles in a variety of human disorders, including Parkinson's disease (PD). PD is characterized by the selective loss of dopaminergic neurons in PD-