Zobrazeno 1 - 10
of 563
pro vyhledávání: '"Yoshinori, Takahashi"'
Autor:
Shunsuke Tsuge, Hiroshi Fujii, Mami Tamai, Hiromasa Tsujiguchi, Misaki Yoshida, Nobuhiro Suzuki, Yoshinori Takahashi, Akari Takeji, Shigeto Horita, Yuhei Fujisawa, Takahiro Matsunaga, Takeshi Zoshima, Ryo Nishioka, Hiromi Nuka, Satoshi Hara, Yukiko Tani, Yasunori Suzuki, Kiyoaki Ito, Kazunori Yamada, Satoshi Nakazaki, Akinori Hara, Atsushi Kawakami, Hiroyuki Nakamura, Ichiro Mizushima, Yasunori Iwata, Mitsuhiro Kawano
Publikováno v:
Arthritis Research & Therapy, Vol 26, Iss 1, Pp 1-11 (2024)
Abstract Background Elevated serum immunoglobulin G4 (IgG4) concentrations are one of the characteristic findings in IgG4-related disease (IgG4-RD). This study investigated the frequency of elevated serum IgG4 levels and associated factors in a gener
Externí odkaz:
https://doaj.org/article/f373ad2e42f444e7ad973a1ab86a9f22
Autor:
Kouta Hamamoto, Xinwen Liang, Ayako Ito, Matthew Lanza, Van Bui, Jiawen Zhang, David M. Opozda, Tatsuya Hattori, Longgui Chen, David Haddock, Fumiaki Imamura, Hong-Gang Wang, Yoshinori Takahashi
Publikováno v:
Cell Reports, Vol 43, Iss 12, Pp 115016- (2024)
Summary: Macroautophagy (autophagy) involves the formation of phagophores that mature into autophagosomes. The impact of inhibiting autophagosome closure remains unclear. Here, we report the generation and analysis of mice with impaired autophagosome
Externí odkaz:
https://doaj.org/article/cdf50fa4202448a6a58ad97af521bbd5
Autor:
Kunihiko Kanatsu, Yoshinori Takahashi, Tetsuya Sakaguchi, Dae-Shik Kim, Miki Murota, Mingde Shan, Kazuki Fukami, Wataru Itano, Kenji Kikuta, Hikaru Yoshimura, Toshiki Kurokawa, Yuko Nagayama, Rena Ishikawa, Ryo Dairiki, Zhi Zhou, Kristen Sanders, Jacob Stupalski, So Yasui, Diana Liu, Farid Benayoud, Hui Fang, Enxuan Jing, Makoto Ogo, Francis G. Fang, John Wang, Hyeong-wook Choi
Publikováno v:
Molecular Therapy: Nucleic Acids, Vol 36, Iss 1, Pp 102404- (2025)
Antisense oligonucleotides (ASOs) are an important class of therapeutics to treat genetic diseases, and expansion of this modality to neurodegenerative disorders has been an active area of research. To realize chronic administration of ASO therapeuti
Externí odkaz:
https://doaj.org/article/48fa025010654763a422d4a52be32434
Autor:
Yansheng Ye, Xinwen Liang, Guifang Wang, Maria C. Bewley, Kouta Hamamoto, Xiaoming Liu, John M. Flanagan, Hong-Gang Wang, Yoshinori Takahashi, Fang Tian
Publikováno v:
Communications Biology, Vol 7, Iss 1, Pp 1-12 (2024)
Abstract VPS37A, an ESCRT-I complex component, is required for recruiting a subset of ESCRT proteins to the phagophore for autophagosome closure. However, the mechanism by which VPS37A is targeted to the phagophore remains obscure. Here, we demonstra
Externí odkaz:
https://doaj.org/article/7b61343f9bb54627aa319eae0a20bf13
Autor:
Hajime Sanada, Satoshi Hara, Makoto Horita, Hiroyuki Kawahara, Misaki Yoshida, Yoshinori Takahashi, Shunsuke Tsuge, Takeshi Zoshima, Ryo Nishioka, Kiyoaki Ito, Ichiro Mizushima, Takashi Matsushita, Mitsuhiro Kawano
Publikováno v:
BMC Nephrology, Vol 24, Iss 1, Pp 1-6 (2023)
Abstract Background Scleroderma renal crisis (SRC) is a critical kidney involvement of systemic sclerosis (SSc), often resulting in end-stage renal disease. Although the recurrence of SRC in the allograft has been reported, the development of de novo
Externí odkaz:
https://doaj.org/article/b9e5a80ade584a4f8110ceb5cd6a9e04
Autor:
Yasuaki Tamaki, Kazuta Yamashita, Daiki Nakajima, Yasuyuki Omichi, Yoshinori Takahashi, Michihiro Takai, Shunsuke Tamaki, Tomohiro Goto, Hiroaki Hayashi, Kosaku Higashino, Yoshihiro Tsuruo, Koichi Sairyo
Publikováno v:
Journal of Occupational Medicine and Toxicology, Vol 18, Iss 1, Pp 1-6 (2023)
Abstract Background Fluoroscopy is indispensable when determining appropriate and effective interventions in orthopedic surgery. On the other hand, there is growing concern about the health hazards of occupational radiation exposure. The aim of this
Externí odkaz:
https://doaj.org/article/7c53161ecada457786f963c2ceae6760
Autor:
Kazuta Yamashita, Yasuaki Tamaki, Daiki Nakajima, Yasuyuki Omichi, Yoshinori Takahashi, Michihiro Takai, Tomohiro Goto, Hiroaki Hayashi, Kosaku Higashino, Yoshihiro Tsuruo, Koichi Sairyo
Publikováno v:
Spine Surgery and Related Research, Vol 7, Iss 4, Pp 341-349 (2023)
Introduction: The harmful effects of long-term low-dose radiation have been well known. There are few comprehensive reports evaluating concrete real exposure doses for each part of a surgeon, assistant surgeon, scrub nurse, and anesthesiologist assoc
Externí odkaz:
https://doaj.org/article/cd4d19222a844a65a25213c649b9a2d8
Publikováno v:
Balkan Medical Journal, Vol 41, Iss 1, Pp 74-75 (2024)
Externí odkaz:
https://doaj.org/article/721f7ae24f054cb78011da4d46d61ba1
Autor:
Yoshikazu Kuboi, Yuta Suzuki, Sotaro Motoi, Chiyuki Matsui, Naoki Toritsuka, Tomoya Nakatani, Kazuhiro Tahara, Yoshinori Takahashi, Yoko Ida, Ayaka Tomimatsu, Motohiro Soejima, Toshio Imai
Publikováno v:
Molecular Therapy: Nucleic Acids, Vol 31, Iss , Pp 339-351 (2023)
Complement component 5 (C5), an important molecule in the complement cascade, blockade by antibodies shows clinical efficacy in treating complement-mediated disorders. However, insufficient blockading induced by single-nucleotide polymorphisms in the
Externí odkaz:
https://doaj.org/article/559a07afa4574d66976dbd1708b7edec
Autor:
Masataka Ono, Satomi Watari, Mizuho Nishizawa-Higashi, Tatsuya Konishi, Yoshinori Takahashi, Hiroki Saeki, Ga-Hyun Joe
Publikováno v:
Food Chemistry: Molecular Sciences, Vol 6, Iss , Pp 100165- (2023)
Water-soluble protein (WSP) from fish meat is abundant in the waste effluent generated via the surimi manufacturing process. This study investigated the anti-inflammatory effects and mechanisms of fish WSP using primary macrophages (MΦ) and animal i
Externí odkaz:
https://doaj.org/article/9f72f4b5a94b4cbc96853c2f5fa23e81