Zobrazeno 1 - 5
of 5
pro vyhledávání: '"Yoshinobu Maruyama"'
Publikováno v:
Journal of Pharmaceutical Sciences. 98:3088-3098
Heat-induced changes in secondary structures of five proteins (bovine serum albumin, BSA; human serum albumin, HSA; myoglobin; ribonuclease A, RNase A; and, β-lactoglobulin, β-Lg) in an amorphous sugar matrix were analyzed by temperature-scanning F
Autor:
Yoshinobu Maruyama, Ken Ichi Ohyama, Hiroyuki Imanaka, Kazuhiro Nakanishi, Koreyoshi Imamura, Kazuko Tani, Toru Yokoyama
Publikováno v:
Spectroscopy Letters. 41:305-312
In an amorphous mixture of sugar and polyvinylpyrrolidone (PVP), PVP carbonyl groups form hydrogen bonds with sugar hydroxyl groups, thereby improving the physical stability of the amorphous matrix against a glass-to-rubber transition. Herein, Fourie
Autor:
Hiroyuki Imanaka, Yoshinobu Maruyama, Tohru Yokoyama, Koreyoshi Imamura, Kazuhiro Nakanishi, Kazuhiro Tanaka
Publikováno v:
Journal of Pharmaceutical Sciences. 97:2789-2797
True density of an amorphous matrix represents the state of molecular packing in the matrix, which is closely related to the physical/chemical properties of the material. Dry gas pycnometry is one possible technique for measuring the true density of
Autor:
Seiji Ogawa, Yoko Asano, Tohru Yokoyama, Koreyoshi Imamura, Yoshinobu Maruyama, Mayo Nomura, Kazuhiro Nakanishi
Publikováno v:
Journal of Pharmaceutical Sciences. 97:1301-1312
The characteristics of hydrogen bond formation between trehalose and polyvinylpyrrolidone (PVP) in amorphous mixtures at different hydration states were quantitatively investigated. Amorphous trehalose-PVP mixtures were prepared by freeze-drying and
Autor:
Toru Yokoyama, Kazuhiro Nakanishi, Yoshinobu Maruyama, Hiroyuki Imanaka, Ken Ichi Ohyama, Koreyoshi Imamura
Publikováno v:
Journal of pharmaceutical sciences. 97(1)
The impact of a polymer additive (polyvinylpyrrolidone, PVP) on hydrogen bonding in amorphous sugar matrices as well as on the glass transition temperature, T(g), were examined by temperature scanning Fourier transform infrared spectroscopy (TS-FTIR)