Zobrazeno 1 - 10
of 706
pro vyhledávání: '"Yoshinobu Baba"'
Autor:
Tomoyoshi Asano, Hidetaka Suga, Hirohiko Niioka, Hiroshi Yukawa, Mayu Sakakibara, Shiori Taga, Mika Soen, Tsutomu Miwata, Hiroo Sasaki, Tomomi Seki, Saki Hasegawa, Sou Murakami, Masatoshi Abe, Yoshinori Yasuda, Takashi Miyata, Tomoko Kobayashi, Mariko Sugiyama, Takeshi Onoue, Daisuke Hagiwara, Shintaro Iwama, Yoshinobu Baba, Hiroshi Arima
Publikováno v:
Communications Biology, Vol 7, Iss 1, Pp 1-10 (2024)
Abstract We use three-dimensional culture systems of human pluripotent stem cells for differentiation into pituitary organoids. Three-dimensional culture is inherently characterized by its ability to induce heterogeneous cell populations, making it d
Externí odkaz:
https://doaj.org/article/d551d71fc6304c17b70e315e54a568e2
Autor:
Saho Morita, Mayumi Iwatake, Sakura Suga, Kazuomi Takahashi, Kazuhide Sato, Chika Miyagi-Shiohira, Hirofumi Noguchi, Yoshinobu Baba, Hiroshi Yukawa
Publikováno v:
Scientific Reports, Vol 14, Iss 1, Pp 1-10 (2024)
Abstract Pulmonary fibrosis is a progressive disease caused by interstitial inflammation. Treatments are extremely scarce; therapeutic drugs and transplantation therapies are not widely available due to cost and a lack of donors, respectively. Recent
Externí odkaz:
https://doaj.org/article/edcf9faab1cb4f9b9b1576910eac4523
Autor:
Akira Yokoi, Kosuke Yoshida, Hirotaka Koga, Masami Kitagawa, Yukari Nagao, Mikiko Iida, Shota Kawaguchi, Min Zhang, Jun Nakayama, Yusuke Yamamoto, Yoshinobu Baba, Hiroaki Kajiyama, Takao Yasui
Publikováno v:
Nature Communications, Vol 14, Iss 1, Pp 1-15 (2023)
Abstract Extracellular vesicles (EVs), including exosomes, are recognized as promising functional targets involved in disease mechanisms. However, the intravital heterogeneity of EVs remains unclear, and the general limitation for analyzing EVs is th
Externí odkaz:
https://doaj.org/article/6312690b91f54645a8ac7a36d9cbb92e
Publikováno v:
Biosensors, Vol 14, Iss 7, p 340 (2024)
Intracellular and extracellular sensing of physical and chemical variables is important for disease diagnosis and the understanding of cellular biology. Optical sensing utilizing fluorescent nanodiamonds (FNDs) is promising for probing intracellular
Externí odkaz:
https://doaj.org/article/a797740bb7aa415f860944f1af1e8bd1
Publikováno v:
Scientific Reports, Vol 13, Iss 1, Pp 1-10 (2023)
Abstract Arrays of small reaction containers, ranging from 624 femtoliters (10–15 L) to 270 attoliters (10–18 L), for capturing a single enzyme molecule and measuring the activity were developed along with a new reversible sealing system based on
Externí odkaz:
https://doaj.org/article/63ba76ef6cdc45eab499501d0c10e494
Autor:
Yaichi Kawakatsu, Ryo Okada, Mitsuo Hara, Hiroki Tsutsui, Naoki Yanagisawa, Tetsuya Higashiyama, Akihide Arima, Yoshinobu Baba, Ken-ichi Kurotani, Michitaka Notaguchi
Publikováno v:
Plant Phenomics, Vol 6 (2024)
Plants are exposed to a variety of environmental stress, and starvation of inorganic phosphorus can be a major constraint in crop production. In plants, in response to phosphate deficiency in soil, miR399, a type of microRNA (miRNA), is up-regulated.
Externí odkaz:
https://doaj.org/article/e63e5986fdba45629ce7c566bbd7873f
Autor:
Hiromasa Tanaka, Daijiro Iwata, Yuki Shibata, Tetsunari Hase, Daisuke Onoshima, Naoyuki Yogo, Hirofumi Shibata, Mitsuo Sato, Kenji Ishikawa, Ikuo Nagasawa, Yoshinori Hasegawa, Makoto Ishii, Yoshinobu Baba, Masaru Hori
Publikováno v:
Scientific Reports, Vol 13, Iss 1, Pp 1-9 (2023)
Abstract Various liquid biopsy methods have been developed for the non-invasive and early detection of diseases. In particular, the detection of circulating tumor cells (CTCs) and cancer-associated fibroblasts (CAFs) in blood has been receiving a gre
Externí odkaz:
https://doaj.org/article/691b5df5199a459b98fac9e5ddf5e7bd
Autor:
Shota Yamada, Hiroshi Yukawa, Koudai Kitamura, Toshiki Mizumaki, Yasuma Yoshizumi, Tomomi Oohara, Eri Nanizawa, Fumika Hirano, Kazuhide Sato, Ayae Sugawara-Narutaki, Tetsuya Ishikawa, Yoshinobu Baba
Publikováno v:
Cell Transplantation, Vol 32 (2023)
Stem cell therapy plays an important role in regenerative therapy; however, there is little information on the in vivo dynamics of transplanted stem cells and the influence of the inflammation of affected tissues or organs on these dynamics. In this
Externí odkaz:
https://doaj.org/article/575644be54b54be2b8665453f0852e52
Autor:
Ryosuke Hayasaka, Sho Tabata, Masako Hasebe, Satsuki Ikeda, Tomoya Hikita, Chitose Oneyama, Jun Yoshitake, Daisuke Onoshima, Kumiko Takahashi, Takahiro Shibata, Koji Uchida, Yoshinobu Baba, Tomoyoshi Soga, Masaru Tomita, Akiyoshi Hirayama
Publikováno v:
Frontiers in Molecular Biosciences, Vol 9 (2023)
Cancer-derived small extracellular vesicles (sEVs) are multifunctional particles with a lipid bilayer structure that are involved in cancer progression, such as malignant proliferation, distant metastasis, and cancer immunity evasion. The separation
Externí odkaz:
https://doaj.org/article/ae8ad54e7a964820a6d9d622d040ef46
Autor:
Kazuomi Takahashi, Hirotoshi Yasui, Shunichi Taki, Misae Shimizu, Chiaki Koike, Kentaro Taki, Hiroshi Yukawa, Yoshinobu Baba, Hisataka Kobayashi, Kazuhide Sato
Publikováno v:
Bioengineering & Translational Medicine, Vol 7, Iss 3, Pp n/a-n/a (2022)
Abstract Ideal cancer treatments specifically target and eradicate tumor cells without affecting healthy cells. Therefore, antibody‐based therapies that specifically target cancer antigens can be considered ideal cancer therapies. Antibodies linked
Externí odkaz:
https://doaj.org/article/2ae3aea3e871468695cc473f1ce95104