Výsledky vyhledávání - "Yoshinobu, Miyatsu"

Freeze-dried equine-derived redback spider antivenom: a local irritation study by intramuscular injection in rabbits and a repeated-dose toxicity study in rats

Autor: Satomi Harano, Toru Hifumi, Motohide Takahashi, Noriko Shinya, Hisashi Taki, Ayataka Nagano, Takayuki Matsumura, Akihiko Yamamoto, Kyouko Sawabe, Yoshinobu Miyatsu, Manabu Ato

Publikováno v: Journal of Toxicologic Pathology

The redback spider (Latrodectus hasseltii) is nonindigenous to Japan but has now spread throughout the country. Bites to humans are rare but can be fatal. We prepared freeze-dried redback spider antivenom for therapeutic use against bites in Japan by

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::08e605eac6e3711b9350fe4403e9e89b
https://doi.org/10.1293/tox.2017-0053

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Venom and Antivenom of the Redback Spider (Latrodectus hasseltii) in Japan. Part I. Venom Extraction, Preparation, and Laboratory Testing

Autor: Haruhiko Isawa, Shigemi Mori, Takayuki Matsumura, Manabu Ato, Tomomi Sato, Kentaro Itokawa, Kyoko Sawabe, Kohei Ogawa, Toru Hifumi, Hisashi Taki, Akira Horita, Akihiko Yamamoto, Akihiro Ginnaga, Reona Mashiko, Motohide Takahashi, Yoshinobu Miyatsu, Yoshihide Maekawa

Publikováno v: Japanese Journal of Infectious Diseases. 71:116-121

The redback spider (Latrodectus hasseltii Thorell) reportedly invaded Japan in September 1995. To date, 84 redback spider bite cases have been reported; 7 of these cases employed the antivenom. Antivenom has been imported from Australia in the past,

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::daa2000f6cffae731973b1c478724e64
https://doi.org/10.7883/yoken.jjid.2017.291

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Retrospective survey to evaluate the safety and efficacy of Japanese botulinum antitoxin therapy in Japan

Autor: Motohide Takahashi, Masaaki Iwaki, Shunji Kozaki, Keita Mottate, Shigemi Mori, Yasushi Torii, Akihiro Ginnaga, Hiroyuki Yokote, Yoshinobu Miyatsu, Akira Horita

Publikováno v: Toxicon. 110:12-18

Japanese botulinum antitoxins have been used for more than 50 years; however, their safety and therapeutic efficacy are not clear. In order to analyze the available data on botulinum antitoxin therapy in Japan, we surveyed published reports about bot

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::5c61a5e3e70658006e41713cd6edecb2
https://doi.org/10.1016/j.toxicon.2015.11.010

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Venom and Antivenom of the Redback Spider (Latrodectus hasseltii) in Japan. Part I. Venom Extraction, Preparation, and Laboratory Testing

Autor: Takayuki, Matsumura, Reona, Mashiko, Tomomi, Sato, Kentaro, Itokawa, Yoshihide, Maekawa, Kohei, Ogawa, Haruhiko, Isawa, Akihiko, Yamamoto, Shigemi, Mori, Akira, Horita, Akihiro, Ginnaga, Yoshinobu, Miyatsu, Motohide, Takahashi, Hisashi, Taki, Toru, Hifumi, Kyoko, Sawabe, Manabu, Ato

Publikováno v: Japanese journal of infectious diseases. 71(2)

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=pmid________::7ee80f6766a06a56223f00baca7c8934
https://pubmed.ncbi.nlm.nih.gov/29491237

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Venom and Antivenom of the Redback Spider (Latrodectus hasseltii) in Japan. Part II. Experimental Production of Equine Antivenom against the Redback Spider

Autor: Satoru Arai, Takayuki Matsumura, Kyoko Sawabe, Toru Hifumi, Hisashi Taki, Takuya Yamagishi, Akira Horita, Shigemi Mori, Manabu Ato, Keigo Shibayama, Yoshinobu Miyatsu, Akihiro Ginnaga, Akihiko Yamamoto, Motohide Takahashi

Publikováno v: Japanese journal of infectious diseases. 70(6)

This is the first report on large-scale experimental production of an equine antivenom against the redback spider (Latrodectus hasseltii) lived in Japan. We captured 10,000 redback spiders in Japan and prepared the toxoids of crude venom extract, mix

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::5e41f075a4b9822aafdac2311af76b5a
https://pubmed.ncbi.nlm.nih.gov/29093316

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Large-Scale Production of Major House Dust Mite Allergen Der f 2 Mutant (C8/119S) in Escherichia coli

Autor: Satoshi Koyanagi, Toshihiro Maeda, Hiroshi Mizokami, Toshio Murakami, Kenjirou Kawatsu, Yoshinobu Miyatsu, Keishin Sugawara

Publikováno v: Journal of Bioscience and Bioengineering. 106:387-392

Hyposensitization, in which causative antigens of allergic diseases are injected, is the sole means of a radical cure for allergic diseases. Since the therapeutic allergens currently used are naturally extracted, producing preparations with a stable

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::28ac0dc8f18f6ed5daff2f2bc283fd65
https://doi.org/10.1263/jbb.106.387

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Production-scale purification of the recombinant major house dust mite allergen Der f 2 mutant C8/119S

Autor: Hiroshi Okamura, Toshio Murakami, Kenjirou Kawatsu, Toshihiro Maeda, Keishin Sugawara, Hiroshi Mizokami, Yoshiaki Oda, Yoshinobu Miyatsu, Satoshi Koyanagi

Publikováno v: Journal of bioscience and bioengineering. 110(5)

A WHO position paper states that allergen immunotherapy is an effective treatment for allergic diseases, and well characterized allergens should be used in immunotherapy. The house dust mite is a major cause of allergic disease. However, the biologic

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c99c9cb20686da3c5d4c6d9e903b02d5
https://pubmed.ncbi.nlm.nih.gov/20547344

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Characterization of the Recombinant Der F 2 Mutant C8/119S and Evaluation of C8/119S in a Rder F 2-Sensitized Rhinitis Mice Model

Autor: Toshio Murakami, Hiroshi Mizokami, Yoshinobu Miyatsu, Satoshi Koyanagi, Keishin Sugawara, Kazuyuki Nakashima, Toshihiro Maeda

Publikováno v: Journal of Allergy & Therapy.

Immunotherapy is the only curative approach to treat allergy, but carries the risk of anaphylaxis. C8/119S is a mutant of Der f 2, which is one of the causative allergens of perennial allergic diseases, and has been selected to decrease the risk of a

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::587ee46d7d7eec7d952d72c1d13979d9
https://doi.org/10.4172/2155-6121.1000105

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Translocation of hepatitis B virus core particles through nuclear pores in transformed yeast cells

Autor: Hiroshi Mizokami, Yoshinobu Miyatsu, Kanji Takeo, Masashi Yamaguchi, Lele Matsuoka

Publikováno v: Journal of electron microscopy. 45(4)

In our previous transmission electron microscopic study of hepatitis B virus core antigen in transformed yeast cells, we observed core particles passing through the nuclear pores. We have now analyzed 1,421 nuclear pores in transformed yeast, and con

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::144db52dfb5ec30e97860748e6018be0
https://pubmed.ncbi.nlm.nih.gov/8888587

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Dynamics of hepatitis B virus core antigen in a transformed yeast cell: analysis with an inducible system

Autor: Masaaki Kawase, Hisako Tanaka, Keishin Sugahara, Masashi Yamaguchi, Yoshikane Horikawa, Yoshinobu Miyatsu, Hiroshi Mizokami

Publikováno v: Journal of electron microscopy. 43(6)

Transformed yeast cells expressing hepatitis B virus core antigen (HBcAg) were found to accumulate abundant core particles in the same way as human hepatocytes infected with hepatitis B virus (HBV) by the present authors. We, therefore, offer a good

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ab6a28f2be03a23fe0502ebebc6aec63
https://pubmed.ncbi.nlm.nih.gov/7722431

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