Zobrazeno 1 - 10
of 300
pro vyhledávání: '"Yoshinobu, Hirose"'
Autor:
Kazuki Nishimura, Kiyoshi Takahara, Kazumasa Komura, Mitsuaki Ishida, Kensuke Hirosuna, Ryoichi Maenosono, Masahiko Ajiro, Moritoshi Sakamoto, Kengo Iwatsuki, Yuki Nakajima, Takuya Tsujino, Kohei Taniguchi, Tomohito Tanaka, Teruo Inamoto, Yoshinobu Hirose, Fumihito Ono, Yoichi Kondo, Akihide Yoshimi, Haruhito Azuma
Publikováno v:
npj Precision Oncology, Vol 8, Iss 1, Pp 1-8 (2024)
Abstract Hyper progressive disease (HPD) is a paradoxical phenomenon characterized by accelerated tumor growth following treatment with immune checkpoint inhibitors. However, the pathogenic causality and its predictor remain unknown. We herein report
Externí odkaz:
https://doaj.org/article/8552f31aaae046989d490218ab175216
Autor:
Toshinori Kobayashi, Mitsuaki Ishida, Hisanori Miki, Nobuyuki Yamamoto, Takashi Harino, Takuki Yagyu, Soshi Hori, Masahiko Hatta, Yuki Hashimoto, Masaya Kotsuka, Makoto Yamasaki, Kentaro Inoue, Yoshinobu Hirose, Mitsugu Sekimoto
Publikováno v:
Scientific Reports, Vol 14, Iss 1, Pp 1-10 (2024)
Abstract Prognostic stratification is an urgent concern for patients with colorectal cancer (CRC). The desmoplastic reaction (DR) is speculated to mirror the tumor microenvironment. DR types are considered independent prognostic indicators in CRC, bu
Externí odkaz:
https://doaj.org/article/42272085c4964f66bde0fe7ca00cc868
Autor:
Shiori Naruoka, Souhei Sakata, Shigeru Kawabata, Yasuyuki Hashiguchi, Eriko Daikoku, Shoichi Sakaguchi, Fumiyoshi Okazaki, Kento Yoshikawa, John F. Rawls, Takashi Nakano, Yoshinobu Hirose, Fumihito Ono
Publikováno v:
Heliyon, Vol 10, Iss 18, Pp e37510- (2024)
In the process of investigating synaptic changes happening to mutants lacking postsynaptic receptors in the neuromuscular junction, we focused on a hitherto uncharacterized zebrafish gene zgc153932 whose expression was increased in the RNAseq and dro
Externí odkaz:
https://doaj.org/article/48649a7e2c4b41a4852a793a3ccdd31e
Autor:
Kazumasa Komura, Kensuke Hirosuna, Satoshi Tokushige, Takuya Tsujino, Kazuki Nishimura, Mitsuaki Ishida, Takuo Hayashi, Ayako Ura, Takaya Ohno, Shogo Yamazaki, Keita Nakamori, Shoko Kinoshita, Ryoichi Maenosono, Masahiko Ajiro, Yuki Yoshikawa, Tomoaki Takai, Takeshi Tsutsumi, Kohei Taniguchi, Tomohito Tanaka, Kiyoshi Takahara, Tsuyoshi Konuma, Teruo Inamoto, Yoshinobu Hirose, Fumihito Ono, Yuichi Shiraishi, Akihide Yoshimi, Haruhito Azuma
Publikováno v:
Molecular Cancer, Vol 22, Iss 1, Pp 1-16 (2023)
Abstract Background Currently, only limited knowledge is available regarding the phenotypic association between fibroblast growth factor receptor 3 (FGFR3) alterations and the tumor microenvironment (TME) in bladder cancer (BLCA). Methods A multi-omi
Externí odkaz:
https://doaj.org/article/44ae7691b7154435adafb64297a43998
Autor:
Yuki Kobayashi, Kazuma Sugahara, Yosuke Takemoto, Junko Tsuda, Yoshinobu Hirose, Makoto Hashimoto, Hiroshi Yamashita
Publikováno v:
PeerJ, Vol 11, p e15562 (2023)
Background Aminoglycoside antibiotics are used for treating certain acute infections. However, these drugs cause ototoxicity by inducing inner ear hair cell death. Aims/Objectives We investigated the protective effect of a nanoemulsion of the caroten
Externí odkaz:
https://doaj.org/article/a4b0f17ea6654c0fa7e9c3ead4126a19
Autor:
Kosei Kimura, Shigeru Kawabata, Hiroyo Oku, Ayana Ikari, Tomo Tominaga, Saki Takai, Junna Sakane, Michiaki Tanaka, Chinatsu Aoki, Monika Ota, Erika Minami, Yoshinobu Hirose, Sang-Woong Lee, Mitsuhiko Iwamoto
Publikováno v:
Journal of Medical Case Reports, Vol 16, Iss 1, Pp 1-5 (2022)
Abstract Background Accessory breast carcinomas of the axilla of males are rare, and primary breast neuroendocrine tumors (BNETs) are rare as well. We present a case of a BNET arising in the axilla of a man. Case presentation A 64-year-old Japanese m
Externí odkaz:
https://doaj.org/article/f00ca4e8ae79496187112d0091c15723
Autor:
Shota Fujii, Mitsuaki Ishida, Kazumasa Komura, Kazuki Nishimura, Takuya Tsujino, Tomohito Saito, Yohei Taniguchi, Tomohiro Murakawa, Haruhito Azuma, Yoshinobu Hirose
Publikováno v:
Diagnostics, Vol 13, Iss 24, p 3636 (2023)
Carcinoma in situ (CIS) of the urinary tract comprises 1–3% of all urothelial malignancies and is often a precursor to muscle-invasive urothelial carcinoma (UC). This study aimed to examine the expression profiles of preferentially expressed antige
Externí odkaz:
https://doaj.org/article/5dd23e32abb04d1ebb5e30dccc707b64
Autor:
Masataka Taniuchi, Ryo Kawata, Tetsuya Terada, Masaaki Higashino, Hiromi Nishimura, Yoshitaka Kurisu, Hiroko Kuwabara, Yoshinobu Hirose
Publikováno v:
Laryngoscope Investigative Otolaryngology, Vol 7, Iss 3, Pp 766-773 (2022)
Abstract Objective Mucoepidermoid carcinoma (MEC) is the most common malignancy of the parotid gland, but the outcome depends on the histological grade. Therefore, the aim of this study was to evaluate MEC on the basis of histological grade. Study De
Externí odkaz:
https://doaj.org/article/8644b73453b64eeb819e0adef06a47e1
Autor:
Masanori Mikuni, Makiko Wakuta, Tatsuya Masaki, Yoshinobu Hirose, Hiroyuki Takasu, Hiroo Kawano, Ren Aoki, Manami Ota, Kazuhiro Kimura
Publikováno v:
American Journal of Ophthalmology Case Reports, Vol 25, Iss , Pp 101353- (2022)
Purpose: We present a case of a gastrointestinal stromal tumor (GIST) metastasis of the rectal primary resisting chemotherapy to the right orbit 15 years after excision of the primary lesion. Observations: A 79-year-old man was diagnosed with rectal
Externí odkaz:
https://doaj.org/article/5f0d1b8133184d318078625b90c51b8a
Autor:
Motomasa Furuse, Hiroko Kuwabara, Naokado Ikeda, Yasuhiko Hattori, Tomotsugu Ichikawa, Naoki Kagawa, Kenichiro Kikuta, Sho Tamai, Mitsutoshi Nakada, Toshihiko Wakabayashi, Masahiko Wanibuchi, Toshihiko Kuroiwa, Yoshinobu Hirose, Shin-Ichi Miyatake
Publikováno v:
BMC Cancer, Vol 20, Iss 1, Pp 1-12 (2020)
Abstract Background The prevalence of programmed death-ligand 1 (PD-L1) and PD-L2 expression on tumor cells and tumor-infiltrating immune cells in primary central nervous system lymphoma (PCNSL) remains unclear. In the present study, we analyzed need
Externí odkaz:
https://doaj.org/article/739ac5ffd30b4c9aaf0c973677d44c6b