Zobrazeno 1 - 10
of 26
pro vyhledávání: '"Yoshino Kubota"'
Autor:
Yasuhiro Hirano, Yusuke Ohno, Yoshino Kubota, Tatsuo Fukagawa, Akio Kihara, Tokuko Haraguchi, Yasushi Hiraoka
Publikováno v:
Journal of Cell Science. 136
Maintaining the integrity of the nuclear envelope (NE) is essential for preventing genomic DNA damage. Recent studies have shown that enzymes that catalyze lipid synthesis are involved in NE maintenance, but the underlying mechanism remains unclear.
Autor:
Yasuhiro Hirano, Yasuha Kinugasa, Yoshino Kubota, Chikashi Obuse, Tokuko Haraguchi, Yasushi Hiraoka
Publikováno v:
The Journal of Biochemistry.
The nuclear envelope (NE) is a double-membrane structure consisting of inner and outer membranes that spatially separate the nucleus from the cytoplasm, and its function is critical for cellular functions such as genome maintenance. In the fission ye
Autor:
Hiroko Osakada, Yasuha Kinugasa, Yasuhiro Hirano, Tokuko Haraguchi, Tomoko Shindo, Shinsuke Shibata, Yoshino Kubota, Yasushi Hiraoka
Publikováno v:
Communications Biology, Vol 3, Iss 1, Pp 1-14 (2020)
Communications Biology
Communications Biology
The nuclear envelope (NE) continues to the endoplasmic reticulum (ER). Proper partitioning of NE and ER is crucial for cellular activity, but the key factors maintaining the boundary between NE and ER remain to be elucidated. Here we show that the co
Publikováno v:
Nucleic Acids Research
The centromeres of many eukaryotic chromosomes are established epigenetically on potentially variable tandem repeats; hence, these chromosomes are at risk of being acentric. We reported previously that artificially created acentric chromosomes in the
Publikováno v:
Nucleic Acids Research
UV radiation induces two major types of DNA lesions, cyclobutane pyrimidine dimers (CPDs) and 6-4 pyrimidine-pyrimidine photoproducts, which are both primarily repaired by nucleotide excision repair (NER). Here, we investigated how chronic low-dose U
Publikováno v:
Molecular and Cellular Biology. 30(No. 20):4840-4850
Differential posttranslational modification of proliferating cell nuclear antigen (PCNA) by ubiquitin or SUMO plays an important role in coordinating the processes of DNA replication and DNA damage tolerance. Previously it was shown that the loss of
Publikováno v:
Molecular and Cellular Biology. 26:5509-5517
Proliferating cell nuclear antigen (PCNA), a sliding clamp required for processive DNA synthesis, provides attachment sites for various other proteins that function in DNA replication, DNA repair, cell cycle progression and chromatin assembly. It has
Autor:
Ken Kurokawa, Masatomo Najima, Atsushi Yamashita, Teruo Yasunaga, Hideo Shinagawa, Shigenobu Kimura, Masayuki Nakano, Kenshiro Oshima, Tetsuya Iida, Kozo Makino, Yoshio Iijima, Kenichi Tagomori, Katsushi Yokoyama, Yoshino Kubota, Takayuki Uda, Takeshi Honda, Masahira Hattori
Publikováno v:
The Lancet. 361:743-749
Summary Background Vibrio parahaemolyticus , a gram-negative marine bacterium, is a worldwide cause of food-borne gastroenteritis. V parahaemolyticus strains of a few specific serotypes, probably derived from a common clonal ancestor, have lately cau
Escherichia coli RecN is an SMC (structural maintenance of chromosomes) family protein that is required for DNA double-strand break (DSB) repair. Previous studies show that GFP-RecN forms nucleoid-associated foci in response to DNA damage, but the me
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0e8e54c406f6777612be907a3196cfcd
https://europepmc.org/articles/PMC3795224/
https://europepmc.org/articles/PMC3795224/
Autor:
Katsushi Yokoyama, Takeshi Honda, Chihiro Sasakawa, Sigenobu Kimura, Tetsuya Iida, Hideo Shinagawa, Ken Kurokawa, Kozo Makino, Kazuo Ishii, Masahiro Hattori, Koichiro Yamamoto, Ichiro Tatsuno, Makoto Onishi, Chikako H. Yutsudo, Yoshino Kubota, Tetsuya Hayashi, Hiroyuki Abe, Teruo Yasunaga
Publikováno v:
Genes & Genetic Systems. 74:227-239
The enterohemorrhagic Escherichia coli (EHEC) O157:H7 strain RIMD 0509952, derived from an outbreak in Sakai city, Japan, in 1996, produces two kinds of verotoxins, VT1 and VT2, encoded by the stx1 and stx2 genes. In the EHEC strains, as well as in o