Zobrazeno 1 - 10
of 14
pro vyhledávání: '"Yoshinari Saito"'
Autor:
Akiko Ebihara, Daiju Iwata, Shigeyuki Kon, Kazuya Iwabuchi, Kazunori Onoé, Toshimitsu Uede, Junko Morimoto, Hirokuni Kitamei, Shigeaki Ohno, Kenichi Namba, Susumu Ishida, Yoshinari Saito, Nobuyoshi Kitaichi, Kazuhiko Yoshida, Mizuki Kitamura
Publikováno v:
Experimental Eye Research. 90:41-48
Osteopontin (OPN) is elevated during the progression of experimental autoimmune uveoretinitis (EAU) in C57BL/6 (B6) mice. Furthermore, EAU symptoms are ameliorated in OPN knockout mice or in B6 mice treated with anti-OPN antibody (M5). Recently, OPN
Autor:
Yoshinari Saito, Masashi Kanayama, Koji Suzuki, Tsuyoshi Asano, Toshimitsu Uede, Hong Mei Li, Tanenobu Harada, Yosuke Nakayama, Shigeyuki Kon, Akio Minami, Norimasa Iwasaki, Tadaaki Miyazaki, Daisuke Kurotaki, Koyu Ito, Junko Morimoto, Jun Uehara, Chiemi Kimura, Yutaka Matsui
Publikováno v:
The Journal of Immunology. 182:8015-8025
Osteopontin is critically involved in rheumatoid arthritis; however, the molecular cross-talk between osteopontin and joint cell components that leads to the inflammatory joint destruction is largely unknown. We found that not only osteopontin but al
Autor:
Hong Yan Diao, Yoshinari Saito, Yosuke Nakayama, Shigeyuki Kon, Koyu Ito, Toshimitsu Uede, Masashi Kanayama, Junko Morimoto, Daisuke Kurotaki, Chiemi Kimura, Yutaka Matsui
Publikováno v:
Matrix Biology. 28:11-19
Osteopontin (OPN) contains at least two major integrin recognition domains, Arg159-Gly-Asp161 (RGD) and Ser162-Val-Val-Tyr-Gly-Leu-Arg168 (SVVYGLR), recognized by alphavbeta3 and alpha5beta1 and alpha4 and alpha9 integrins, respectively. OPN is speci
Autor:
Naoki Fukuda, Chiemi Kimura, Hongyan Diao, Yutaka Matsui, Shigeyuki Kon, Daisuke Kurotaki, Yosuke Nakayama, Toshimitsu Uede, Eiko Ohtsuka, Yukio Fujiwara, Koyu Ito, Yasuo Komatsu, Masashi Kanayama, Yoshinari Saito
Publikováno v:
Human Gene Therapy. 18:1205-1214
Osteopontin (OPN) has been implicated in various helper T cell type 1 immunity-mediated diseases including rheumatoid arthritis (RA), multiple sclerosis (MS), Crohn's disease, and fulminant hepatitis. Increased expression of OPN has been detected in
Autor:
Hirofumi Sawa, Takeharu Minamitani, Kazuhiko Takahashi, Gen Takebe, Yoshinari Saito, Hiroyoshi Ariga, Takanori Nishimura, Mami Sato, Tomoki Ikuta, Ken-ichi Matsumoto, Fumio Nakamura
Publikováno v:
Experimental Cell Research. 298:305-315
Tenascin-X (TNX) is an extracellular matrix glycoprotein. We previously demonstrated that TNX regulates the expression of type VI collagen. In this study, we investigated the binding of TNX to type I collagen as well as to type VI collagen and the ef
Autor:
Fumie Iraha, Mitsugu Maéno, Yumi Izutsu, Yoshinari Saito, Ira O. Daar, Keiko Yoshida, Masatoki Kawakami
Publikováno v:
Development, Growth and Differentiation. 44:395-407
In an effort to elucidate the regulatory mechanisms that determine the fate of blood cells and vascular cells in the ventral blood island mesoderm, the embryonic expression of Xtie-2, a Xenopus homolog of the tie-2 receptor tyrosine kinase, was exami
Publikováno v:
Surface and Interface Analysis. 25:650-659
A series of equations have been proposed to calculate take-off angle dependency of the elemental composition of layer-structured models from the experimentally obtained peak intensities of XPS. We have measured the take-off angle dependency of XPS pe
Autor:
Hongyan Diao, Junko Morimoto, David T. Denhardt, Toshimitsu Uede, Lanjuan Li, Yoshinari Saito, Kazunori Onoé, Kazuya Iwabuchi, Luc Van Kaer, Susan R. Rittling, Shigeyuki Kon
Publikováno v:
Proceedings of the National Academy of Sciences of the United States of America. 105(41)
Invariant natural killer T (iNKT) cells belong to a subset of lymphocytes bridging innate and acquired immunity. We demonstrated that osteopontin (OPN) is involved in the activation of iNKT cells. In the present work, we examined whether OPN affects
Publikováno v:
Cell and tissue research. 335(2)
We have previously isolated a cDNA clone coding for Xenopus AP-2rep (activator protein-2 repressor), a member of the Kruppel-like factor family, and reported its expression pattern in developing Xenopus embryos. In the present study, the physiologica
Publikováno v:
Comparative biochemistry and physiology. Part B, Biochemistrymolecular biology. 126(2)
We demonstrated previously that Xmsx-1 is involved in mesoderm patterning along the dorso-ventral axis, under the regulation of BMP-4 signaling. When Xmsx-1 RNA was injected into the dorsal blastomeres, a mass of muscle tissue formed instead of notoc