Zobrazeno 1 - 10
of 19
pro vyhledávání: '"Yoshinari Ichiki"'
Autor:
Yuichiro Ishiyama, Johji Kato, Toru Shimokubo, Kenji Kuwasako, Kazuo Kitamura, Shigeru Nakamura, Yoshinari Ichiki, Miho Tanaka, Tanenao Eto, Kenji Kangawa
Publikováno v:
American Journal of Hypertension. 8:997-1000
Adrenomedullin (AM) is a novel hypotensive peptide originally isolated from the pheochromocytoma tissue of humans. To examine the pathophysiological role of AM in primary aldosteronism (PA), the plasma concentration of AM in patients with PA was meas
Autor:
Osamu Kida, Tanenao Eto, Yoshinari Ichiki, Yuichiro Ishiyama, Kazuo Kitamura, Kenji Kangawa, Junichiro Sakata
Publikováno v:
Clinical and Experimental Pharmacology and Physiology. 22:614-618
SUMMARY 1. The haemodynamic effects of rat adrenomedullin (AM), a novel hypotensive peptide, were examined in anaesthetized 16–18 week old spontaneously hypertensive rats (SHR) and Wistar-Kyoto rats (WKY). 2. An intravenous injection of rat AM dose
Autor:
Kazuo, Kitamura, Kenji, Kangawa, Mari, Kawamoto, Yoshinari, Ichiki, Shigeru, Nakamura, Hisayuki, Matsuo, Tanenao, Eto
Publikováno v:
Biochemical and biophysical research communications. 425(3)
Autor:
Tanenao Eto, Johji Kato, Yoshinari Ichiki, Takao Ayabe, Kazuo Kitamura, Toshihiro Kita, Noboru Tamaki, Takuma Etoh, Naoto Yokota
Publikováno v:
Clinical and Experimental Hypertension
Concerns about metabolic complications often disturb prolonged use of diuretics in Japan. We investigated 3-year safety and efficacy in Japanese patients with hypertension who were uncontrolled with angiotensin receptor blocker or angiotensin-convert
Autor:
Yoshinari Ichiki, Hisayuki Matsuo, Kenji Kangawa, Tetsuya Eto, Yamamoto Y, Kazuo Kitamura, Hisanori Washimine
Publikováno v:
Biochemical and Biophysical Research Communications. 202:1081-1087
Proadrenomedullin N-terminal 20 peptide (PAMP) is a candidate for a novel biologically active peptide processed from proadrenomedullin. This study clearly demonstrates the existence of PAMP in vivo that had been deduced from analysis of cDNA. To iden
Autor:
Yoshinari Ichiki, Tanenao Eto, Mari Kawamoto, Shigeru Nakamura, Kazuo Kitamura, Hisayuki Matsuo, Kenji Kangawa
Publikováno v:
Biochemical and Biophysical Research Communications. 192:553-560
A novel hypotensive peptide was discovered in human pheochromocytoma by monitoring the elevating activity of platelet cAMP. Since this peptide is abundant in normal adrenal medulla as well as in pheochromocytoma tissue arising from adrenal medulla, i
Publikováno v:
Biochemical and Biophysical Research Communications. 191:961-967
In this study we investigated peptides that increase rat platelet cAMP in porcine thyroid gland. Gel filtration of extracts from porcine thyroid gland showed high and low molecular weight activity. Low molecular weight activity contained peptides, in
Autor:
Kazuo Kitamura, Naoto Yokota, Johji Kato, Toshihiro Kita, Noboru Tamaki, Yoshinari Ichiki, Takao Ayabe, Tanenao Eto, Takuma Etoh
Publikováno v:
Hypertension research : official journal of the Japanese Society of Hypertension. 33(4)
The long-term antihypertensive efficacy and safety of losartan/hydrochlorothiazide (HCTZ) combinations have not been appropriately evaluated in Japan. In this study, treated hypertensive patients taking angiotensin-receptor blocker (ARB) or angiotens
Autor:
Kenji Kangawa, Miho Tanaka, Tanenao Eto, Yoshinari Ichiki, Shumpei Sakakibara, Mari Kawamoto, Kazuo Kitamura, Hisayuki Matsuo, Junji Emura
Publikováno v:
FEBS Letters. 341:288-290
A specific and sensitive radioimmunoassay for adrenomedullin has been developed. Half-maximal inhibition of binding of radioiodinated adrenomedullin was observed at 4 tool/tube. The radioimmunoassay recognized the entire adrenomedullin molecule and h
Autor:
Johji Kato, Kenji Kangawa, Kazuo Kitamura, Tanenao Eto, Hisayuki Matsuo, Yoshinari Ichiki, Kenji Kuwasako
Publikováno v:
Biochemical and biophysical research communications. 211(2)
Proadrenomedullin N-terminal 20 peptide (PAMP) is a novel hypotensive peptide found in adrenomedullin precursor. Using a radioimmunoassay for human PAMP, we purified immunoreactive PAMP (ir-PAMP) from human pheochromocytoma and determined its complet