Zobrazeno 1 - 10
of 32
pro vyhledávání: '"Yoshinaka Murai"'
Publikováno v:
Heliyon, Vol 6, Iss 12, Pp e05830- (2020)
The depression of evoked fast excitatory postsynaptic potentials (EPSPs) following superfusion with various concentrations (3 μM-5 mM) of ammonium chloride (NH4Cl) were investigated in rat hippocampal CA1 neurons. The amplitude of the evoked fast EP
Externí odkaz:
https://doaj.org/article/20ce8c7055bd4018b5b93b81953f8b51
Publikováno v:
Heliyon
Heliyon, Vol 6, Iss 12, Pp e05830-(2020)
Heliyon, Vol 6, Iss 12, Pp e05830-(2020)
The depression of evoked fast excitatory postsynaptic potentials (EPSPs) following superfusion with various concentrations (3 μM-5 mM) of ammonium chloride (NH4Cl) were investigated in rat hippocampal CA1 neurons. The amplitude of the evoked fast EP
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f048ba7c73ee0983f4b628e58df26911
http://europepmc.org/articles/PMC7773873
http://europepmc.org/articles/PMC7773873
Publikováno v:
Neuroscience Letters. 636:120-126
Oxygen and glucose deprivation (OGD) elicits a rapid and irreversible depolarization with a latency of ∼5 min in intracellular recordings of hippocampal CA1 neurons in rat slice preparations. In the present study, we examined the role of cathepsin
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c214aeb52cda1bf221a31a881e113a47
https://doi.org/10.1016/j.neulet.2016.11.006
https://doi.org/10.1016/j.neulet.2016.11.006
Autor:
Munetake Yoshitomi, Yoshinaka Murai, Nobuyuki Takeshige, Motohiro Morioka, Salunya Tancharoen, Kiyoshi Kikuchi, Eiichiro Tanaka
Publikováno v:
International Journal of Molecular Sciences, Vol 14, Iss 7, Pp 13909-13930 (2013)
International Journal of Molecular Sciences
International Journal of Molecular Sciences
Edaravone was originally developed as a potent free radical scavenger, and has been widely used to treat acute ischemic stroke in Japan since 2001. Free radicals play an important role in the pathogenesis of a variety of diseases, such as cardiovascu
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::7f6d188a707fdb19e47c35ad112603fa
http://www.mdpi.com/1422-0067/14/7/13909
http://www.mdpi.com/1422-0067/14/7/13909
Autor:
Eiichiro Tanaka, Naoki Miura, Ko-ichi Kawahara, Paul A. Lapchak, Motohiro Morioka, Yoshinaka Murai, Kiyoshi Kikuchi
Publikováno v:
Biomedical Reports. 1:7-12
Acute ischemic stroke (AIS) is a major cause of morbidity and mortality in the aging population worldwide. Alteplase, a recombinant tissue plasminogen activator, is the only Food and Drug Administration-approved thrombolytic agent for the treatment o
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f52d71f6f97739971757f80a16a2e465
https://doi.org/10.3892/br.2012.7
https://doi.org/10.3892/br.2012.7
Publikováno v:
International Journal of Molecular Sciences, Vol 13, Iss 6, Pp 7739-7761 (2012)
International Journal of Molecular Sciences
International Journal of Molecular Sciences
Stroke is an enormous public health problem with an imperative need for more effective therapies. In therapies for ischemic stroke, tissue plasminogen activators, antiplatelet agents and anticoagulants are used mainly for their antithrombotic effects
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::fed886a816b7d163f099a342a624f6d6
http://www.mdpi.com/1422-0067/13/6/7739
http://www.mdpi.com/1422-0067/13/6/7739
Autor:
Tomoyuki Takahashi, Toyojiro Matsuishi, Ken-ichiro Kosai, Yasunori Okabe, Eiichiro Tanaka, Yoshinaka Murai, Akira Kusaga, Hideho Higashi, Chiaki Mitsumasu
Publikováno v:
Brain Research. 1360:17-27
Mutations in methyl-CpG-binding protein 2 (MeCP2) gene cause the neurodevelopmental disorder Rett syndrome (RTT). Here, we describe a new experimental system that efficiently elucidates the role of MeCP2 in neural development. MeCP2-null and control
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::bb10202c90cd098a63ed62f13a2b56a4
https://doi.org/10.1016/j.brainres.2010.08.090
https://doi.org/10.1016/j.brainres.2010.08.090
Autor:
Yoshinaka Murai, Hideho Higashi, Eiichiro Tanaka, Koki Shimoji, Yasunori Okabe, Aya Yamada, Tatsuhiko Kano, Toshiyuki Tobita
Publikováno v:
Neuroscience Research. 64:391-396
In humans, peripheral somatosensory information converges upon dorsal horn neurons in the spinal cord, which can be recorded from the dorsal epidural space as spinal cord potentials (SCPs) following segmental dorsal root stimulation (SS) employing ep
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::565a3c9cee1bfd99786ec64009ffd14d
https://doi.org/10.1016/j.neures.2009.04.012
https://doi.org/10.1016/j.neures.2009.04.012
Publikováno v:
Biochemistry & Analytical Biochemistry.
In 2012, stroke was the second most common cause of death worldwide. One in 10 people with stroke die in hospital, and many more suffer ongoing disability, which highlights the need for more effective treatments.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::03413563022ea72876696f0a7e1f9f90
https://doi.org/10.4172/2161-1009.1000244
https://doi.org/10.4172/2161-1009.1000244
Publikováno v:
Biochemistry & Analytical Biochemistry.
Alteplase (recombinant tissue plasminogen activator) is the only licensed drug for acute ischemic stroke (AIS) treatment, but only 3–5% of patients with AIS receive thrombolytic treatment using alteplase. Further breakthroughs are needed for thromb
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::7cde69e15854ca1e3607f85239d7d6db
https://doi.org/10.4172/2161-1009.1000250
https://doi.org/10.4172/2161-1009.1000250