The Fungal Metabolite (+)-Terrein Abrogates Inflammatory Bone Resorption via the Suppression of TNF-α Production in a Ligature-Induced Periodontitis Mouse Model.

Autor: Sako H; Department of Periodontics and Endodontics, Division of Dentistry, Okayama University Hospital, Okayama 700-8558, Japan., Omori K; Department of Pathophysiology-Periodontal Science, Graduate School of Medicine, Dentistry and Pharmaceutical Sciences, Okayama University, Okayama 700-8525, Japan., Nakayama M; Department of Oral Microbiology, Graduate School of Medicine, Dentistry and Pharmaceutical Sciences, Okayama University, Okayama 700-8525, Japan., Mandai H; Department of Pharmacy, Faculty of Pharmacy, Gifu University of Medical Science, Gifu 509-0261, Japan., Ideguchi H; Department of Pathophysiology-Periodontal Science, Graduate School of Medicine, Dentistry and Pharmaceutical Sciences, Okayama University, Okayama 700-8525, Japan., Yoshimura-Nakagawa S; Department of Periodontics and Endodontics, Division of Dentistry, Okayama University Hospital, Okayama 700-8558, Japan., Sakaida K; Department of Periodontics and Endodontics, Division of Dentistry, Okayama University Hospital, Okayama 700-8558, Japan., Nagata-Kamei C; Department of Pathophysiology-Periodontal Science, Graduate School of Medicine, Dentistry and Pharmaceutical Sciences, Okayama University, Okayama 700-8525, Japan., Kobayashi H; Department of Pathophysiology-Periodontal Science, Graduate School of Medicine, Dentistry and Pharmaceutical Sciences, Okayama University, Okayama 700-8525, Japan., Ishii S; Division of Applied Chemistry, Graduate School of Natural Sciences and Technology, Okayama University, Okayama 700-8530, Japan., Ono M; Department of Molecular Biology and Biochemistry, Graduate School of Medicine, Dentistry and Pharmaceutical Sciences, Okayama University, Okayama 700-8558, Japan., Ibaragi S; Department of Oral and Maxillofacial Surgery and Biopathology, Graduate School of Medicine, Dentistry and Pharmaceutical Sciences, Okayama University, Okayama 700-8525, Japan., Yamamoto T; Department of Pathophysiology-Periodontal Science, Graduate School of Medicine, Dentistry and Pharmaceutical Sciences, Okayama University, Okayama 700-8525, Japan., Suga S; Division of Applied Chemistry, Graduate School of Natural Sciences and Technology, Okayama University, Okayama 700-8530, Japan., Takashiba S; Department of Pathophysiology-Periodontal Science, Graduate School of Medicine, Dentistry and Pharmaceutical Sciences, Okayama University, Okayama 700-8525, Japan.

Publikováno v: Journal of fungi (Basel, Switzerland) [J Fungi (Basel)] 2023 Mar 03; Vol. 9 (3). Date of Electronic Publication: 2023 Mar 03.

Terrein: Isolation, synthesis, and upscaling of a functional scaffold for multifaceted biomedical applications.

Autor: Raghuvanshi, Vaishali, Katiyar, Diksha

Publikováno v: Medicinal Chemistry Research; Dec2024, Vol. 33 Issue 12, p2236-2251, 16p