Zobrazeno 1 - 10
of 165
pro vyhledávání: '"Yoshimoto Sekine"'
Autor:
Nobuhisa Kanahara, Taisuke Yoshida, Yasunori Oda, Hiroshi Yamanaka, Toshihiro Moriyama, Hideaki Hayashi, Takayuki Shibuya, Yasunori Nagaushi, Takashi Sawa, Yoshimoto Sekine, Eiji Shimizu, Makoto Asano, Masaomi Iyo
Publikováno v:
PLoS ONE, Vol 8, Iss 6, p e67273 (2013)
BACKGROUNDAlthough the duration of untreated psychosis (DUP) plays an important role in the short-term prognosis of patients with schizophrenia, their long-term prognosis generally is not determined by DUP alone. It is important to explore how other
Externí odkaz:
https://doaj.org/article/41ea912bce6445ed8eb97dd7d2b5929d
Autor:
Ichiro Sora, Yoshimoto Sekine, Masaomi Iyo, Hiroshi Ujike, Naohisa Uchimura, Mitsuhiko Yamada, Nakao Iwata, Toshiya Inada, Norio Ozaki, Masanari Itokawa, Hideaki Kobayashi
Publikováno v:
ResearcherID
Current Neuropharmacology
Current Neuropharmacology
There is a growing evidence that serotoninergic systems modulate dopaminergic neurotransmission. We analyzed the association between the variations in the brain tryptophan hydroxylase 2 (TPH2) gene, a rate limiting enzyme for serotonin biosynthesis,
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d560054990767916543d72b2e60fbc73
https://doi.org/10.2174/157015911795017335
https://doi.org/10.2174/157015911795017335
Autor:
Toshiya Inada, Norio Ozaki, Yoshimoto Sekine, Yasuhide Iwata, Masaomi Iyo, Hiroshi Ujike, Katsuaki Suzuki, Norio Mori, Mutsuo Harano, Kazuhiko Nakamura, Mitsuhiko Yamada, Nakao Iwata, Ayyappan Anitha, Noriyoshi Takei, Tokutaro Komiyama, Ichiro Sora
Publikováno v:
Neuroscience Letters. 455:120-123
Methamphetamine continues to be the most widely abused drug in Japan. Chronic methamphetamine users show psychiatric signs, including methamphetamine psychosis. Monoamine oxidase A (MAOA) is one of the major enzymes responsible for the degradation of
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::4d7e5b5b45d2f3f2fd38a254a06d3a8d
https://doi.org/10.1016/j.neulet.2009.02.048
https://doi.org/10.1016/j.neulet.2009.02.048
Autor:
Hideaki Hayashi, Toshihiko Ohkami, Yoshitaka Uchida, Goro Fukami, Takuya Asaka, Takayuki Shibuya, Tsuyoshi Sasaki, Tasuku Hashimoto, Hiroyuki Watanabe, Eiji Shimizu, Masaomi Iyo, Kenji Hashimoto, Yukihiko Shirayama, Nobuhisa Kanahara, Yoshimoto Sekine, Hiroshi Yamanaka, Makoto Asano, Ryosuke Miyatake, Mihisa Fujisaki
Publikováno v:
Progress in Neuro-Psychopharmacology and Biological Psychiatry. 33:410-415
Although to date there have been no conclusive pathophysiological findings in support of the degenerative theory of the etiology of schizophrenia, the results of neuroimaging studies have suggested that progressive changes in the brain do occur durin
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::050eeeed14609363f229ccbe0f88fb73
https://doi.org/10.1016/j.pnpbp.2008.12.017
https://doi.org/10.1016/j.pnpbp.2008.12.017
Autor:
Tokutaro Komiyama, Nobuhisa Kanahara, Hiroshi Ujike, Ryosuke Miyatake, Kenji Hashimoto, Norio Ozaki, Mitsuhiko Yamada, Ichiro Sora, Mutsuo Harano, Nakao Iwata, Toshiya Inada, Yoshimoto Sekine, Masaomi Iyo
Publikováno v:
American Journal of Medical Genetics Part B: Neuropsychiatric Genetics. :233-238
Accumulating evidence suggests that phosphatidylinositol (PI) pathways have been involved in the secretion of dopamine (DA) and the regulation of DA transporter, which is a target of methamphetamine (METH). A recent large-scale gene-association study
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::9c05a5bd6cd538b94e6e0843f51c37ea
https://doi.org/10.1002/ajmg.b.30797
https://doi.org/10.1002/ajmg.b.30797
Autor:
Mitsuhiko Yamada, Tokutaro Komiyama, Yoshio Yamanouchi, Hiroshi Ujike, Masaomi Iyo, Yoko Kinoshita, Toshiya Inada, Nakao Iwata, Toru Hori, Ichiro Sora, Norio Ozaki, Taro Kishi, Masashi Ikeda, Mutsuo Harano, Yoshimoto Sekine, Tsuyoshi Kitajima, Kunihiro Kawashima
Publikováno v:
Annals of the New York Academy of Sciences. 1139:83-88
Abnormal intracellular signaling molecules in dopamine signal transduction are thought to be associated with the pathophysiology of methamphetamine (METH)-use disorder. A recent study reported that a new intracellular protein, prostate apoptosis resp
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f0a1d5800fdef01720900ce6f260efb2
https://doi.org/10.1196/annals.1432.024
https://doi.org/10.1196/annals.1432.024
Autor:
Ichiro Sora, Masashi Ikeda, Yoshimoto Sekine, T. Inada, Mitsuhiko Yamada, Taro Kishi, Yoshio Yamanouchi, Tsuyoshi Kitajima, Kunihiro Kawashima, Toru Hori, Tokutaro Komiyama, Nakao Iwata, Mutsuo Harano, Norio Ozaki, Hiroshi Ujike, Masaomi Iyo, Yoko Kinoshita
Publikováno v:
Annals of the New York Academy of Sciences. 1139:70-82
The mesolimbic system is thought to be involved in the reinforcing action of many addictive drugs and the release of dopamine modulated by neuronal nicotine cholinergic receptors (nAChRs). Several investigations suggested that nAChRs on dopaminergic
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a01fdd1074d7bed5eb451f031d80e105
https://doi.org/10.1196/annals.1432.023
https://doi.org/10.1196/annals.1432.023
Autor:
Takao Toyoda, Katsuaki Suzuki, Nori Takei, Genichi Sugihara, Takeo Yoshikawa, Kenji J. Tsuchiya, Ismail Thanseem, Kazuo Yamada, Taishi Miyachi, Tomoko Toyota, Yoshimi Iwayama, Toshiro Sugiyama, Yasuomi Ouchi, Eiji Hattori, Yoshimoto Sekine, Shiro Suda, Masayoshi Kawai, Ayyappan Anitha, Hideo Matsuzaki, Norio Mori, Masatsugu Tsujii, Yasuhide Iwata, Kazuhiko Nakamura
Publikováno v:
Biochemical and Biophysical Research Communications. 360:715-720
Autism is a pervasive neurodevelopmental disorder diagnosed in early childhood. Growth factors have been found to play a key role in the cellular differentiation and proliferation of the central and peripheral nervous systems. Epidermal growth factor
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::10efa6084e3e5341703b5e35067f1907
https://doi.org/10.1016/j.bbrc.2007.06.051
https://doi.org/10.1016/j.bbrc.2007.06.051
Autor:
Tokutaro Komiyama, Ryosuke Miyatake, Nakao Iwata, Yoshimoto Sekine, Hiroshi Ujike, Masaomi Iyo, Yoichi Mashimo, Toshiya Inada, Ichiro Sora, Eiji Shimizu, Akira Sawa, Yoichi Suzuki, Daisuke Matsuzawa, Mutsuo Harano, Kenji Hashimoto, Yukihiko Shirayama, Kazuhisa Maeda, Mitsuhiko Yamada, Norio Ozaki, Akira Hata
Publikováno v:
American Journal of Psychiatry. 164:1105-1114
Protein interacting with C-kinase-1 (PICK1) plays a role in the targeting and clustering of dopamine transporter, which is the primary target site for the abused drug methamphetamine. Based on the interaction of PICK1 with dopamine transporter, it is
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a33bea3f023388adad20d88719509d00
https://doi.org/10.1176/ajp.2007.164.7.1105
https://doi.org/10.1176/ajp.2007.164.7.1105
Autor:
Yasuhide Iwata, Kenji Hashimoto, Nori Takei, Shiro Suda, Genichi Sugihara, Kazuhiko Nakamura, Angus C. Nairn, Kenji J. Tsuchiya, Yoshimoto Sekine, Norio Mori, Katsuaki Suzuki, Kohji Sato, Yoshio Minabe, Daiichiro Nakahara, Hideo Matsuzaki
Publikováno v:
European Journal of Neuroscience. 25:3376-3384
To clarify whether reelin signaling is involved in dopaminergic neurotransmission in the adult mouse brain, we investigated dopamine function in mice lacking reelin (reeler). We found that methamphetamine-induced locomotor activity is significantly a
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::6e35a369fb3d2b09e3185700e18d4b97
https://doi.org/10.1111/j.1460-9568.2007.05564.x
https://doi.org/10.1111/j.1460-9568.2007.05564.x