Zobrazeno 1 - 10
of 23
pro vyhledávání: '"Yoshimitsu Nakanishi"'
Publikováno v:
Inflammation and Regeneration, Vol 44, Iss 1, Pp 1-10 (2024)
Abstract The neural and immune systems sense and respond to external stimuli to maintain tissue homeostasis. These systems do not function independently but rather interact with each other to effectively exert biological actions and prevent disease p
Externí odkaz:
https://doaj.org/article/7fa71921ea4d49269beba19ad062ca01
Publikováno v:
Inflammation and Regeneration, Vol 43, Iss 1, Pp 1-10 (2023)
Abstract Upon exposure to external stressors, the body senses them and activates the sympathetic nervous system (SNS) to maintain the homeostasis, which is known as the “fight-or-flight” response. Recent studies have revealed that the SNS also pl
Externí odkaz:
https://doaj.org/article/0ca066e8324341b497a0d4c1d547e0b1
Publikováno v:
Inflammation and Regeneration, Vol 42, Iss 1, Pp 1-8 (2022)
Abstract The global prevalence of metabolic diseases, such as obesity, diabetes, and atherosclerosis, is rapidly increasing and has now reached epidemic proportions. Chronic tissue inflammation is a characteristic of these metabolic diseases, indicat
Externí odkaz:
https://doaj.org/article/e2479c4e24174a3d86320df63361a105
Publikováno v:
Inflammation and Regeneration, Vol 42, Iss 1, Pp 1-2 (2022)
Externí odkaz:
https://doaj.org/article/f94f5c0094134a4ca4a7dd4032785ba6
Autor:
Yujiro Naito, Shohei Koyama, Kentaro Masuhiro, Takashi Hirai, Takeshi Uenami, Takako Inoue, Akio Osa, Hirotomo Machiyama, Go Watanabe, Nicolas Sax, Jordan Villa, Yumi Kinugasa-Katayama, Satoshi Nojima, Moto Yaga, Yuki Hosono, Daisuke Okuzaki, Shingo Satoh, Takeshi Tsuda, Yoshimitsu Nakanishi, Yasuhiko Suga, Takayoshi Morita, Kiyoharu Fukushima, Masayuki Nishide, Takayuki Shiroyama, Kotaro Miyake, Kota Iwahori, Haruhiko Hirata, Izumi Nagatomo, Yukihiro Yano, Motohiro Tamiya, Toru Kumagai, Norihiko Takemoto, Hidenori Inohara, Sho Yamasaki, Kazuo Yamashita, Taiki Aoshi, Esra A. Akbay, Naoki Hosen, Yasushi Shintani, Hyota Takamatsu, Masahide Mori, Yoshito Takeda, Atsushi Kumanogoh
Publikováno v:
Science Advances. 9
Immune checkpoint inhibitors (ICIs) have caused revolutionary changes in cancer treatment, but low response rates remain a challenge. Semaphorin 4A (Sema4A) modulates the immune system through multiple mechanisms in mice, although the role of human S
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::1d75f8bfce4dc51fb9d93fdbbf6c1ab5
https://doi.org/10.1126/sciadv.ade0718
https://doi.org/10.1126/sciadv.ade0718
Publikováno v:
International Immunology
Semaphorins were originally identified as axon-guidance molecules essential for neural development. In addition to their functions in the neural system, members of the semaphorin family have critical functions in many pathophysiological processes, in
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c7df1c42d2dd155d488408c587e66eb9
https://doi.org/10.1093/intimm/dxab035
https://doi.org/10.1093/intimm/dxab035
Autor:
Yuya, Shirai, Yoshimitsu, Nakanishi, Akari, Suzuki, Hachirou, Konaka, Rika, Nishikawa, Kyuto, Sonehara, Shinichi, Namba, Hiroaki, Tanaka, Tatsuo, Masuda, Moto, Yaga, Shingo, Satoh, Mayuko, Izumi, Yumiko, Mizuno, Tatsunori, Jo, Yuichi, Maeda, Takuro, Nii, Eri, Oguro-Igashira, Takayuki, Morisaki, Yoichiro, Kamatani, Shingo, Nakayamada, Chikako, Nishigori, Yoshiya, Tanaka, Yoshito, Takeda, Kazuhiko, Yamamoto, Atsushi, Kumanogoh, Yukinori, Okada
Publikováno v:
Annals of the rheumatic diseases.
ObjectivesAutoimmune and allergic diseases are outcomes of the dysregulation of the immune system. Our study aimed to elucidate differences or shared components in genetic backgrounds between autoimmune and allergic diseases.MethodsWe estimated genet
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::75b61f90b8d2f55a0edfabaa234d1491
https://pubmed.ncbi.nlm.nih.gov/35753705
https://pubmed.ncbi.nlm.nih.gov/35753705
Autor:
Maiko Naito, Yoshimitsu Nakanishi, Yasutaka Motomura, Hyota Takamatsu, Shohei Koyama, Masayuki Nishide, Yujiro Naito, Mayuko Izumi, Yumiko Mizuno, Yuta Yamaguchi, Satoshi Nojima, Daisuke Okuzaki, Atsushi Kumanogoh
Publikováno v:
Life Science Alliance. 5:e202201486
Group 2 innate lymphoid cells (ILC2s) have been implicated in both physiologic tissue remodeling and allergic pathology, yet the niche signaling required for ILC2 properties is poorly understood. Here, we show that an axonal guidance cue semaphorin 6
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::54cfa2506ecf14e0728d1ca4c5048a50
https://doi.org/10.26508/lsa.202201486
https://doi.org/10.26508/lsa.202201486
Autor:
Yu Futami, Akio Osa, Hyota Takamatsu, Kotaro Miyake, Yuki Hosono, Shingo Satoh, Izumi Nagatomo, Yuhei Kinehara, Satoshi Nojima, Yasuhiko Suga, Kiyoharu Fukushima, Atsushi Kumanogoh, Taro Koba, Haruhiko Hirata, Yujiro Naito, Yoshito Takeda, Shohei Koyama, Takeshi Nakatani, Takeshi Tsuda, Daisuke Okuzaki, Kota Iwahori, Daisuke Ito, Yoshimitsu Nakanishi, Masayuki Nishide, Takayuki Shiroyama
Publikováno v:
Journal of immunology (Baltimore, Md. : 1950). 207(5)
Cancer immunotherapy has shown great promise as a new standard therapeutic strategy against cancer. However, the response rate and survival benefit remain unsatisfactory because most current approaches, such as the use of immune checkpoint inhibitors
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::95bd63b637e5c84b466062f92163fd5f
https://pubmed.ncbi.nlm.nih.gov/34380650
https://pubmed.ncbi.nlm.nih.gov/34380650
Publikováno v:
Bone. 157:116305
The maintenance of skeletal integrity is tightly regulated by two cell types, bone forming osteoblasts and bone resorbing osteoclasts. Although the role of the nervous system in regulating osteoblasts and osteoclasts was identified over a decade ago,
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::62729ef65606c024996deb28fc20ab84
https://doi.org/10.1016/j.bone.2021.116305
https://doi.org/10.1016/j.bone.2021.116305