Zobrazeno 1 - 10
of 126
pro vyhledávání: '"Yoshimitsu, Mizunoe"'
Autor:
Makoto Mitsunaga, Kimihiro Ito, Takashi Nishimura, Hironori Miyata, Kei Miyakawa, Takeshi Morita, Akihide Ryo, Hisataka Kobayashi, Yoshimitsu Mizunoe, Tadayuki Iwase
Publikováno v:
Communications Biology, Vol 5, Iss 1, Pp 1-10 (2022)
Abstract The continuous emergence of microbial pathogens for which there are no effective antimicrobials threatens global health, necessitating novel antimicrobial approaches. Here, we present a targeted antimicrobial strategy that can be applied to
Externí odkaz:
https://doaj.org/article/e132bbecbc27484cab7574235fe332ae
Publikováno v:
npj Biofilms and Microbiomes, Vol 8, Iss 1, Pp 1-10 (2022)
Abstract Biofilms are surface-bound microbial communities that are typically embedded in a matrix of self-produced extracellular polymeric substances and can cause chronic infections. Extracellular DNA is known to play a crucial role in biofilm devel
Externí odkaz:
https://doaj.org/article/6c26ea13405043f88d3883c70b0e595b
Autor:
Ken-ichi Okuda, Satomi Yamada-Ueno, Yutaka Yoshii, Tetsuo Nagano, Takayoshi Okabe, Hirotatsu Kojima, Yoshimitsu Mizunoe, Yuki Kinjo
Publikováno v:
mBio, Vol 13, Iss 4 (2022)
ABSTRACT Staphylococcus aureus, a major pathogen of community-acquired and nosocomial-associated infections, forms biofilms consisting of extracellular matrix-embedded cell aggregates. S. aureus biofilm formation on implanted medical devices can caus
Externí odkaz:
https://doaj.org/article/09d4bfb4efd843deba8d85b06d4c5876
Autor:
Ken-ichi Okuda, Yutaka Yoshii, Satomi Yamada, Akio Chiba, Ippei Hironaka, Seiji Hori, Katsuhiko Yanaga, Yoshimitsu Mizunoe
Publikováno v:
Annals of Clinical Microbiology and Antimicrobials, Vol 17, Iss 1, Pp 1-10 (2018)
Abstract Background Catheter-related infection (CRI) is one of the serious challenges in clinical practice. This preliminary clinical study aimed to examine whether next-generation sequencing (NGS) targeting 16S rDNA, which was PCR-amplified directly
Externí odkaz:
https://doaj.org/article/a624daab502c45c3aabcb7724d5ce792
Autor:
Yutaka Yoshii, Ken-ichi Okuda, Satomi Yamada, Mari Nagakura, Shinya Sugimoto, Tetsuo Nagano, Takayoshi Okabe, Hirotatsu Kojima, Takeo Iwamoto, Kazuyoshi Kuwano, Yoshimitsu Mizunoe
Publikováno v:
npj Biofilms and Microbiomes, Vol 3, Iss 1, Pp 1-9 (2017)
Biofilm formation: Benefits of selective inhibition A synthetic molecule related to the hormone progesterone might keep medical devices free of biofilms without promoting antibiotic resistance. Implanted devices that have become contaminated with bio
Externí odkaz:
https://doaj.org/article/e42199373d6b4156aca7d9de6a5cd685
Publikováno v:
International Materials Reviews. 68:247-271
Autor:
Ken-ichi Okuda, Ryuichi Nagahori, Satomi Yamada, Shinya Sugimoto, Chikara Sato, Mari Sato, Tadayuki Iwase, Kazuhiro Hashimoto, Yoshimitsu Mizunoe
Publikováno v:
Frontiers in Microbiology, Vol 9 (2018)
The present study aimed to understand the biofilm formation mechanism of Propionibacterium acnes by analyzing the components and structure of the biofilms. P. acnes strains were isolated from the surface of explanted cardiac pacemaker devices that ex
Externí odkaz:
https://doaj.org/article/f6c6bfbf8a3d4e6ea46dd0345b648c33
Hydrophobicity of Residue 128 of the Stress-Inducible Sigma Factor RpoS Is Critical for Its Activity
Publikováno v:
Frontiers in Microbiology, Vol 8 (2017)
RpoS is a key stress-inducible sigma factor that regulates stress resistance genes in Escherichia coli, such as the katE gene encoding catalase HPII and the glg genes encoding glycogen synthesis proteins. Monitoring RpoS activity can provide informat
Externí odkaz:
https://doaj.org/article/bc05ab46df5c4975ba9c63353cc6e249
Autor:
Makoto Mitsunaga, Kimihiro Ito, Takashi Nishimura, Hironori Miyata, Kei Miyakawa, Takeshi Morita, Akihide Ryo, Hisataka Kobayashi, Yoshimitsu Mizunoe, Tadayuki Iwase
Publikováno v:
Communications biology. 5(1)
The continuous emergence of microbial pathogens for which there are no effective antimicrobials threatens global health, necessitating novel antimicrobial approaches. Here, we present a targeted antimicrobial strategy that can be applied to various m
Autor:
Yuki Kinjo, Shinya Sugimoto, Teru Ogura, Kunitoshi Yamanaka, Yurika Terasawa, Yoshimitsu Mizunoe, Tatsuya Niwa
Publikováno v:
Journal of molecular biology. 433(3)
In Escherichia coli, the major bacterial Hsp70 system consists of DnaK, three J-domain proteins (JDPs: DnaJ, CbpA, and DjlA), and nucleotide exchange factor GrpE. JDPs determine substrate specificity for the Hsp70 system; however, knowledge on their