Chitin protects the gut epithelial barrier in a protochordate model of DSS-induced colitis

Autor: Assunta Liberti, Ivana Zucchetti, Daniela Melillo, Diana Skapura, Yoshimi Shibata, Rosaria De Santis, Maria Rosaria Pinto, Gary W. Litman, Larry J. Dishaw

Publikováno v: Biology Open, Vol 7, Iss 1 (2018)

The gastrointestinal tract of Ciona intestinalis, a solitary tunicate that siphon-filters water, shares similarities with its mammalian counterpart. The Ciona gut exhibits other features that are unique to protochordates, including certain immune mol

Externí odkaz: https://doaj.org/article/54aacadf38e4403ab77ca4eca18e5df3

Dietary Chitin Particles Called Mimetic Fungi Ameliorate Colitis in Toll-Like Receptor 2/CD14- and Sex-Dependent Manners

Autor: Johnston C, Dorey Ck, Brian Mercer, Lee Zj, Li Z, Nwadiuto Esiobu, Aiko M. Cirone, Louis P, Jianning Wei, Yoshimi Shibata, Changlong Nan

Publikováno v: Infection and immunity. 87(5)

Chitin is a natural N-acetylglucosamine polymer and a major structural component of fungal cell walls. Dietary chitin is mucoadhesive; anti-inflammatory effects of chitin microparticles (CMPs; 1- to 10-μm diameters) have been demonstrated in models

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::610713933a93e120b11f7111654b673c
https://pubmed.ncbi.nlm.nih.gov/30782858

Optimizing Power Heterogeneous Functional Units for Dynamic and Static Power Reduction

Autor: Yoshimi Shibata, Toshinori Sato

Publikováno v: Electronics, Vol 3, Iss 4, Pp 661-674 (2014)
Electronics
Volume 3
Issue 4
Pages 661-674

Power consumption is the major constraint for modern microprocessor designs. In particular, static power consumption becomes a serious problem as the transistor size shrinks via semiconductor technology improvement. This paper proposes a technique th

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::7da92a3e13af0cfce8821ee47d511f5a
https://doi.org/10.3390/electronics3040661

Chitin protects gut epithelial barrier in a protochordate model of DSS-induced colitis

Autor: Ivana Zucchetti, Rosaria De Santis, Assunta Liberti, Maria Rosaria Pinto, Diana Skapura, Larry J. Dishaw, Yoshimi Shibata, Daniela Melillo, Gary W. Litman

Publikováno v: Biology open 7 (2018). doi:10.1242/bio.029355
info:cnr-pdr/source/autori:Liberti, Assunta; Zucchetti, Ivana; Melillo, Daniela; Skapura, Diana; Shibata, Yoshimi; De Santis, Rosaria; Pinto, Maria Rosaria; Litman, Gary W.; Dishaw, Larry J./titolo:Chitin protects the gut epithelial barrier in a protochordate model of DSS-induced colitis/doi:10.1242%2Fbio.029355/rivista:Biology open/anno:2018/pagina_da:/pagina_a:/intervallo_pagine:/volume:7
Biology Open
Biology Open, Vol 7, Iss 1 (2018)

The gastrointestinal tract of Ciona intestinalis, a solitary tunicate that siphon-filters water, shares similarities with its mammalian counterpart. The Ciona gut exhibits other features that are unique to protochordates, including certain immune mol

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f0af3cd73079f2c0f5ed80fae82eec9b
https://doi.org/10.1242/bio.029355

Chitin enhances obese inflammation ex vivo

Autor: Kathleen N Beasley, Edmund O. Acevedo, David C. Mari, Chun-Jung Huang, Tamekia L. Jones, Yoshimi Shibata, Robert L. Franco

Publikováno v: Human Immunology. 75:41-46

Infection has been implicated as a co-risk factor for obesity, but the mechanism remains uncertain. Elevated levels of plasma chitinase 3-like 1 (CHI3L1) are found in obese individuals. Since CHI3L1 is produced by activated immune cells including mac

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f189330fd3bb9738f3b8b154dbc44489
https://doi.org/10.1016/j.humimm.2013.09.005