Zobrazeno 1 - 10
of 15
pro vyhledávání: '"Yoshimi Jitsumori"'
Autor:
Iori Ohmori, Mamoru Ouchida, Katsuhiro Kobayashi, Yoshimi Jitsumori, Akiko Mori, Hiroyuki Michiue, Teiichi Nishiki, Yoko Ohtsuka, Hideki Matsui
Publikováno v:
Neurobiology of Disease, Vol 50, Iss , Pp 209-217 (2013)
Dravet syndrome is an intractable epileptic syndrome beginning in the first year of life. De novo mutations of SCN1A, which encode the Nav1.1 neuronal voltage-gated sodium channel, are considered the major cause of Dravet syndrome. In this study, we
Externí odkaz:
https://doaj.org/article/d6481db8d63c48708e357eb4461ec7fa
Autor:
Mamoru Ouchida, Hirotaka Kanzaki, Sachio Ito, Hiroko Hanafusa, Yoshimi Jitsumori, Seiji Tamaru, Kenji Shimizu
Publikováno v:
PLoS ONE, Vol 7, Iss 8, p e44095 (2012)
The miR-17-92 cluster encodes 7 miRNAs inside a single polycistronic transcript, and is known as a group of oncogenic miRNAs that contribute to tumorigenesis in several cancers. However, their direct targets remain unclear, and it has been suggested
Externí odkaz:
https://doaj.org/article/dc3d92f85bf544598934624cb7f93ab5
Autor:
Yoshimi Jitsumori, Seito Kawahara, Hiromasa Yamamoto, Hiroshi Katayama, Kaori Sasai, Nagahide Matsubara, Akiko Sakai, Yukiko Yasuda, Akisada Ishizaki, Yoshiya Okano, Kenji Shimizu, Sachio Ito
Publikováno v:
Biomed Rep
NINEIN serves an essential role in centrosome function as a microtubule organizing center, and in the reformation of the interphase centrosome architecture following mitosis. In the present study, the association between NINEIN Pro1111Ala (rs2236316)
Autor:
Hiroyuki Michiue, Teiichi Nishiki, Hideki Matsui, Yoshimi Jitsumori, Katsuhiro Kobayashi, Akiko Mori, Iori Ohmori, Mamoru Ouchida, Yoko Ohtsuka
Publikováno v:
Neurobiology of Disease, Vol 50, Iss, Pp 209-217 (2013)
Dravet syndrome is an intractable epileptic syndrome beginning in the first year of life. De novo mutations of SCN1A, which encode the Na(v)1.1 neuronal voltage-gated sodium channel, are considered the major cause of Dravet syndrome. In this study, w
Autor:
Mamoru Ouchida, Yoshimi Jitsumori, Katsuhiro Kobayashi, Takushi Inoue, Yoko Ohtsuka, Kenji Shimizu, Iori Ohmori, Yoshihiro Maegaki, Hideki Matsui
Publikováno v:
Epilepsia. 49:521-526
Mutations in the SCN 1 A gene, encoding the neuronal voltage-gated sodium channel alpha1 subunit, cause SMEI, GEFS+, and related epileptic syndromes. We herein report the R1575C-SCN 1 A mutation identified in a patient with Rasmussen encephalitis. R1
Autor:
Mamoru Ouchida, Hiroko Hanafusa, Yoshimi Jitsumori, Seiji Tamaru, Hirotaka Kanzaki, Kenji Shimizu, Sachio Ito
Publikováno v:
Proteomics. 11(17)
MicroRNAs (miRNAs) are small non-coding RNAs that post-transcriptionally repress the expression of target genes. Many miRNAs have been implicated in a number of diseases, including cancers. The miR-17-92 miRNA cluster is known as a body of oncogenic
Autor:
Aki Yoshida, Kenji Shimizu, Sachio Ito, Mamoru Ouchida, Kunihiko Numoto, Yoshimi Jitsumori, Norihide Ohata, Toshiyuki Kunisada, Toshifumi Ozaki, Hirotaka Kanzaki
Publikováno v:
International journal of molecular medicine. 18(6)
The molecular pathogenesis of osteosarcoma is very complicated and associated with chaotic abnormalities on many chromosomal arms. We analyzed 12 cases of osteosarcomas with comparative genomic hybridization (CGH) to identify chromosomal imbalances,
Autor:
Kenji Shimizu, Yasuhiro Shiote, Yoshinobu Matsuo, Yoshimi Jitsumori, Fumihiko Ishimaru, Mamoru Ouchida, Yoichiro Ogama, Mitsune Tanimoto
Publikováno v:
International Journal of Molecular Medicine.
Naf1 (Nef-associated factor 1)/TNIP1/ABIN-1 (A20-binding inhibitor of NF-kappaB activation) is a cellular protein that interacts and cooperates with the NFkappaB inhibiting protein A20. It is reported that Naf1 attenuates epidermal growth factor (EGF
Autor:
Tatsuo Ito, Kenji Shimizu, Sachio Ito, Yoshimi Jitsumori, Yuki Morimoto, Mamoru Ouchida, Akira Kawai, Toshifumi Ozaki, Hajime Inoue
Publikováno v:
Laboratory investigation; a journal of technical methods and pathology. 84(11)
Synovial sarcomas are soft-tissue tumors predominantly affecting children and young adults. They are molecular-genetically characterized by the SYT-SSX fusion gene generated from chromosomal translocation t(X; 18) (p11.2; q11.2). When we screened new
Autor:
Hiroshi Sonobe, Aki Yoshida, Hajime Inoue, Mamoru Ouchida, Yuki Morimoto, Yoshimi Jitsumori, Tatsuo Ito, Kenji Shimizu, Toshifumi Ozaki
Publikováno v:
Cancer letters. 224(2)
About 97% of synovial sarcomas harbor the SYT-SSX fusion gene by chromosomal translocation. We found that the histone deacetylase (HDAC) inhibitor FK228 significantly suppressed the growth of synovial sarcoma cells as compared with that of osteosarco