Zobrazeno 1 - 10
of 22
pro vyhledávání: '"Yoshimasa Shimoto"'
Autor:
Satoshi Kunitada, Yoshimasa Shimoto
Publikováno v:
Japanese Journal of Thrombosis and Hemostasis. 20:527-533
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::1c82808a62b4ec681b362fa2cd57ecb8
https://doi.org/10.2491/jjsth.20.527
https://doi.org/10.2491/jjsth.20.527
Autor:
Dolly A. Parasrampuria, Yoshimasa Shimoto, Taro Kanamaru, Satoshi Kunitada, Ian R. Wilding, Koichiro Ogata, Alyson Connor
Publikováno v:
Journal of Clinical Pharmacology
Two studies in healthy subjects assessed the absorption of edoxaban when delivered to specific locations within the gastrointestinal tract using Enterion capsules. In study 1 (single‐dose, 4‐way crossover), 8 participants received edoxaban 60 mg
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f172441a11d7d7531af0dc3aa67ed33a
https://pubmed.ncbi.nlm.nih.gov/25969414
https://pubmed.ncbi.nlm.nih.gov/25969414
Autor:
Juan J. Badimon, Julio I. Osende, Valentin Fuster, Daichi Shimbo, Jonathan Robbins, Julie Chen, Yoshimasa Shimoto, Satoshi Kunitada
Publikováno v:
Thrombosis and Haemostasis. 88:733-738
SummaryRecent evidence suggests that TF may play a causal role in acute coronary syndromes, and may be an important therapeutic target. Several inhibitors of TF, coagulation factors VIIa and Xa are under investigation as novel antithrombotic approach
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e82005207080bca71b7c3ab810a559e9
https://doi.org/10.1055/s-0037-1613294
https://doi.org/10.1055/s-0037-1613294
Autor:
Yasuyuki TAKEDA, Keiichi KAWAGOE, Aki YOKOMIZO, Yoshihiro YOKOMIZO, Toru HOSOKAMI, Yoshimasa SHIMOTO, Yoshiaki TABUCHI, Yoshiyasu OGIHARA, Yuko HONDA, Keiko KAWARABAYASHI, Miki ISERI, Shuichi YOKOHAMA
Publikováno v:
Chemical and Pharmaceutical Bulletin. 47:755-771
In order to improve the biological characteristics of DA-3934 (5), a novel gastrin/cholecystokinin (CCK)-B receptor antagonist, phenoxyacetic acid derivatives replacing the N-methyl-N-phenylcarbamoylmethyl moiety of 5 with various alkyl chains have b
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0f40ab67adeb5103712825d89a2a0cd8
https://doi.org/10.1248/cpb.47.755
https://doi.org/10.1248/cpb.47.755
Autor:
Yoshimasa Shimoto, Hiroto Miwa, Yoshitaka Konda, Tadataka Yamada, Chris J. Dickinson, Ira Gantz
Publikováno v:
Biochemical and Biophysical Research Communications. 200:1214-1220
We report the isolation of a gene encoding a novel member of the family of melanocortin receptors. The mouse melanocortin-5 receptor (mMC5R) responds to melanocortins with an increase in intracellular cyclic 3',5'-adenosine monophosphate (cAMP) conce
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::28af819efd2fabce57cc91dc29852c90
https://doi.org/10.1006/bbrc.1994.1580
https://doi.org/10.1006/bbrc.1994.1580
Autor:
Yoshimasa Shimoto, John DelValle, Yoshitaka Konda, Takao Tashiro, Hiroto Miwa, Stanley J. Watson, T Yamada, Ira Gantz
Publikováno v:
Journal of Biological Chemistry. 268:15174-15179
The recent cloning of three melanocortin receptors suggests an unexpected diversity in this family of seven transmembrane G-protein linked receptors. Herein, we report the cloning, expression, and gene localization of a fourth human melanocortin rece
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::2554d78efcb3389bd0bafa273a7115d8
https://doi.org/10.1016/s0021-9258(18)82452-8
https://doi.org/10.1016/s0021-9258(18)82452-8
Publikováno v:
Phytotherapy Research. 5:201-205
The effects of orally administered soft-shelled turtle powder on experimental liver injury induced by carbon tetrachloride were studied. Activities of transaminases and lactate dehydrogenase, content of albumin in serum, total protein, triglyceride a
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::a618f48ccdaec21775b1b48cd3f98ea1
https://doi.org/10.1002/ptr.2650050503
https://doi.org/10.1002/ptr.2650050503
Autor:
Kei-ichi Kawagoe, Toru Hosokami, Yasuyuki Takeda, Yoshiyasu Ogihara, Yoshiaki Tabuchi, Yokomizo Aki, Rira Otsubo, Shuichi Yokohama, Yuko Honda, Yoshihiro Yokomizo, Yoshimasa Shimoto
Publikováno v:
Chemicalpharmaceutical bulletin. 46(6)
A novel series of phenoxyacetic acid derivatives was synthesized based on considerations of the three-dimensional structural similarity of YM022 and RP72540. The gastrin/cholecystokinin (CCK)-B and CCK-A receptor antagonist activities of these compou
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::97ccf6c810200c83b984bd7e9a0fafc2
https://pubmed.ncbi.nlm.nih.gov/9658573
https://pubmed.ncbi.nlm.nih.gov/9658573
Autor:
Norio Suzuki, Yoshimasa Shimoto, Takuya Ikeda, Hasegawa Masashi, Atsushi Nakayama, Shuichi Yokohama, Yuko Honda, Yoichi Kurebayashi, Shoichiro Ide, Toru Hosokami
Publikováno v:
Chemicalpharmaceutical bulletin. 43(7)
A series of exomethylenic bicyclic thiazoline derivatives (3a--i) was synthesized and evaluated for hepatoprotective activity against galactosamine-induced and monoclonal antibody-induced acute liver injuries in rats. The structure-activity relations
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::aefee9d2dce56728d8963bafa3572b7c
https://pubmed.ncbi.nlm.nih.gov/7586055
https://pubmed.ncbi.nlm.nih.gov/7586055
Autor:
Yoichi Kurebayashi, Shoichiro Ide, Norio Suzuki, Takuya Ikeda, Hasegawa Masashi, Yuko Honda, Atsushi Nakayama, Toru Hosokami, Yoshimasa Shimoto
Publikováno v:
Chemicalpharmaceutical bulletin. 43(1)
A series of bicyclic thiazoline derivatives (4a-s) was synthesized and evaluated for hepatoprotective activity against galactosamine-induced and monoclonal antibody-induced acute liver injuries in rats. The structure-activity relationships were inves
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b851add20b711fc5a2e1f52c800460b6
https://pubmed.ncbi.nlm.nih.gov/7895310
https://pubmed.ncbi.nlm.nih.gov/7895310