Zobrazeno 1 - 10
of 17
pro vyhledávání: '"Yoshimasa Matsunaga"'
Autor:
Akira Kagemoto, Keiko Nambu, Keiko Morimoto, Toshihiko Fujii, Yoshio Esumi, Shin-ichiro Nishiyama, Yoshimasa Matsunaga, Shinya Hanawa, Hisashi Miyazaki
Publikováno v:
Drug Metabolism and Pharmacokinetics. 11:235-249
Autor:
Yoshiaki Terauchi, Hisashi Miyazaki, Yoshimasa Matsunaga, Keiko Morimoto, Hiroshi Toda, Toshihiko Fujii
Publikováno v:
Drug Metabolism and Pharmacokinetics. 11:273-279
Autor:
Hisashi Miyazaki, Toshihiko Fujii, Yoshio Esumi, Keiko Morimoto, Shin-ichiro Nishiyama, Yoshimasa Matsunaga, Shinya Hanawa
Publikováno v:
Drug Metabolism and Pharmacokinetics. 11:250-272
The transfer of radioactivity into the fetus and milk was studied in pregnant and lactating rats, respectively, after a single intravenous administration of [14C]posatirelin. The plasma level, tissue distribution and excretion of radioactivity were i
Autor:
Fumio Okamoto, Yoshimasa Matsunaga, Hisashi Miyazaki, Yasuko Kusaka, Keishiro Kawamura, Takao Tanaka, Fumio Terasaki
Publikováno v:
Journal of Molecular and Cellular Cardiology. 27:1605-1612
Abnormal long-chain fatty acid metabolism has been suggested as having a role in the genesis of certain cardiac diseases, and depressed myocardial long-chain fatty acid uptake has been clinically demonstrated in some patients with hypertrophic cardio
Publikováno v:
Epilepsy Research. 17:233-236
Zonisamide (1,2-benzisoxazole-3-methane sulfonamide) is a new antiepileptic drug developed in Japan. This compound was proven to possess a strong inhibitory effect on convulsions of cortical origin, whether induced by electric or chemical stimuli. Re
Publikováno v:
Journal of Pharmacobio-Dynamics. 14:615-622
Plasma levels of haloperidol decanoate and haloperidol after intramuscular administration of haloperidol decanoate in rats showed good fits with a multi-compartment model which was constituted by combination of 2-compartment models for the dispositio
Publikováno v:
Journal of Plastic, Reconstructive & Aesthetic Surgery. 62:e477-e478
Autor:
Shinzo Nishimura, Yasushi Nakayama, Takao Tanaka, Koichi Sohmiya, Kenro Yoshimoto, Keishiro Kawamura, Yuzo Hirota, Hisashi Miyazaki, Ryoichi Tsuji, Yoshimasa Matsunaga
Publikováno v:
Journal of molecular and cellular cardiology. 25(12)
The leakage of heart-type cytoplasmic fatty acid-binding protein (H-FABP c ) from injured myocardial cells has been reported. We have previously proposed that its plasma and urinary levels could be used as an early indicator of myocardial injury and
Publikováno v:
European Journal of Drug Metabolism and Pharmacokinetics. 4:199-206
Following oral administration of [14C]loperamide hydrochloride in 1 mg/kg to rats, plasma levels of radioactivity reached maximum at 4 hrs and decreased with a half-life of 4.1 hrs. Radioactivity in 96-hr feces accounted for 95% of the dose, with 30%
Autor:
Hisashi Miyazaki, Nobuhito Kobayashi, Keiko Nambu, Masahisa Hashimoto, Yoshinori Oh-E, Yoshimasa Matsunaga
Publikováno v:
European Journal of Drug Metabolism and Pharmacokinetics. 12:183-188
[14C]Haloperidol decanoate was hydrolysed by partially purified carboxylesterase but not in plasma, blood, lymph and lymphatic liquid. These fluids inhibited the enzyme-mediated hydrolysis of the ester. Within the same incubation period as above, the