Zobrazeno 1 - 10
of 19
pro vyhledávání: '"Yoshimasa Ike"'
Publikováno v:
Protein Science. 31
GFP-like chromoproteins (CPs) with non-fluorescence ability have been used as bioimaging probes. Existing CPs have voids in the optical absorption window which limits their extensibility. The development of new CP color is therefore ongoing. Here, we
Publikováno v:
Cell biochemistry and function. 13(4)
Degradation of cyclin B was effectively suppressed when cells were treated with ALLN (N-acetylleucylleucylnorleucinal) which inhibits proteasome, calpain and cysteine proteinase cathepsins. In order to examine which protease degrades cyclin B, the ef
Publikováno v:
European journal of biochemistry. 205(1)
Cystatin alpha was purified from Escherichia coli transfected with a recombinant cystatin alpha gene and injected into the tail vein of rats. Its fate was then followed using a sensitive enzyme immunoassay for cystatin alpha. Results showed that it w
Publikováno v:
Bulletin of the Chemical Society of Japan. 50:2406-2412
The toxicity and tumor affinity of 5-fluorouracil (1) have been modified by the introduction of a carbamoyl group. Carbamoylation by three general methods were studied extensively: (i) The reaction of 1 with isocyanate, (ii) the reaction of 1-chlorof
Publikováno v:
Nucleic Acids Research. 10:1755-1769
A simple solid phase method for the synthesis of oligodeoxyribonucleotides has been developed using the phosphotriester approach. Mononucleotide coupling units are sequentially added to the polystyrene copolymer with 1% divinylbenzene and two kinds o
Autor:
YOSHIO KAJIMURA, HIROO TOYODA, MORIYUKI SATO, SHOICHI MIYAKOSHI, SARA A. KAPLAN, YOSHIMASA IKE, SANNA M. GOYERT, JACK SILVER, DAVID HAWKE, JOHN E. SHIVELY, SIDNEY V. SUGGS, R. BRUCE WALLACE, KEIICHI ITAKURA
Publikováno v:
DNA. 2:175-182
The recent development of the amino acid microsequence technique allows us to obtain partial sequence information using an extremely small amount of protein. Two sets of mixed oligonucleotide probes were chemically synthesized using the amino acid se
Publikováno v:
Chemical and Pharmaceutical Bulletin. 34:893-896
Main metabolites of 1-hexylcarbamoyl-5-fluorouracil, i.e., 1-(5-carboxypentylcarbamoyl)-, 1-(3-carboxypropylcarbamoyl)-, 1-(5-hydroxyhexylcarbamoyl)- and 1-(5-oxohexylcarbamoyl)-5-fluorouracils, were synthesized on a large scale.
Publikováno v:
Nucleic Acids Research. 11:477-488
A solid phase method for the simultaneous synthesis of mixed oligonucleotides using a phosphotriester approach has been developed. For this synthesis, a mixture of mono or dimeric coupling units is used, and a slight difference in the reactivity of t
Publikováno v:
Tetrahedron Letters. 10:4547-4550
Publikováno v:
Tetrahedron Letters. 10:4543-4546