Zobrazeno 1 - 10
of 314
pro vyhledávání: '"Yoshimasa ITO"'
Autor:
Kazuyuki Fukushima, Hiroyuki Higashiyama, Yuji Kazuta, Keisuke Hashimoto, Naoto Watanabe, Yoshiaki Furuya, Yoshimasa Ito, Ting Wu, Takashi Kosasa, Delia M. Talos, Yeri Song, Nicholas S. Roberts, Frances E. Jensen, Takahisa Hanada, Katsutoshi Ido
Publikováno v:
Epilepsia Open, Vol 8, Iss 3, Pp 834-845 (2023)
Abstract Objective As of 2022, 36 anti‐seizure medications (ASMs) have been licensed for the treatment of epilepsy, however, adverse effects (AEs) are commonly reported. Therefore, ASMs with a wide margin between therapeutic effects and AEs are pre
Externí odkaz:
https://doaj.org/article/f701ca4aa9704aca88c101bf7dd510b7
Autor:
Koki Kato, Tomohiro Mizuno, Takenao Koseki, Yoshimasa Ito, Kazuo Takahashi, Naotake Tsuboi, Shigeki Yamada
Publikováno v:
Frontiers in Pharmacology, Vol 13 (2022)
Information on immune checkpoint inhibitor-induced vasculitides is limited, and predictors for this condition have not been identified. Therefore, we have examined the frequency of immune checkpoint inhibitor-induced vasculitides by analyzing the dat
Externí odkaz:
https://doaj.org/article/06b230a4c1804afb9c22464295d35eab
Autor:
Michiaki Okuda, Ichiro Hijikuro, Yuki Fujita, Xiaofeng Wu, Shinichi Nakayama, Yoko Sakata, Yuji Noguchi, Makoto Ogo, Shigeru Akasofu, Yoshimasa Ito, Yoshiyuki Soeda, Nobuhiko Tsuchiya, Naoki Tanaka, Takashi Takahashi, Hachiro Sugimoto
Publikováno v:
PLoS ONE, Vol 10, Iss 2, p e0117511 (2015)
In tauopathies, a neural microtubule-associated protein tau (MAPT) is abnormally aggregated and forms neurofibrillary tangle. Therefore, inhibition of the tau aggregation is one of the key approaches for the treatment of these diseases. Here, we have
Externí odkaz:
https://doaj.org/article/156b0a940cc84ded874d5a15e2573c9b
Publikováno v:
PLoS ONE, Vol 7, Iss 5, p e36853 (2012)
BACKGROUND: Brains of patients with schizophrenia show both neurodevelopmental and functional deficits that suggest aberrant glutamate neurotransmission. Evidence from both genetic and pharmacological studies suggests that glutamatergic dysfunction,
Externí odkaz:
https://doaj.org/article/3a06d25e40314c08aa8affbfafff051b
Autor:
Nicholas S. Roberts, Marcus J. Handy, Yoshimasa Ito, Keisuke Hashimoto, Frances E. Jensen, Delia M. Talos
Publikováno v:
Epilepsy & Behavior. 143:109194
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::9a236b970a24482b7f80a0fdc6246c7f
https://doi.org/10.1016/j.yebeh.2023.109194
https://doi.org/10.1016/j.yebeh.2023.109194
Autor:
Shigeki Yamada, Kazuo Takahashi, Tomohiro Mizuno, Masakazu Hatano, Koki Kato, Takenao Koseki, Naotake Tsuboi, Yoshimasa Ito
Publikováno v:
In Vivo
Background/Aim: Concomitant proton pump inhibitor (PPI) and immune checkpoint inhibitor (ICPI) were determined as risk factors of acute kidney injury. To identify the type of PPI associated with ICPI-induced nephritis, we used the Japanese Adverse Dr
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::051a820b09b14e976056d5d4fc0ec78c
https://doi.org/10.21873/invivo.12570
https://doi.org/10.21873/invivo.12570
Detection and identification of potential transglutaminase 2 substrates in the mouse renal glomeruli
Autor:
Yukio Yuzawa, Kazuo Takahashi, Hisateru Yamaguchi, Yoshimasa Ito, Kiyotaka Hitomi, Hideki Tatsukawa
Publikováno v:
Archives of Biochemistry and Biophysics. 660:11-19
The glomerulus primarily comprises mesangial cells, glomerular microvascular endothelial cells, and podocytes. IgA nephropathy is the most common primary glomerulonephritis worldwide and has a risk of progression to end-stage renal disease. IgA nephr
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2a5169dff35eff09f7d50f24a19e4276
https://doi.org/10.1016/j.abb.2018.10.001
https://doi.org/10.1016/j.abb.2018.10.001
Autor:
Tomoyuki Aoyama, Noriaki Kikuchi, Hiromi Fujita, Yusuke Ono, Taro Sugawara, Tadashi Hasegawa, Yumika Ito, Yoshimasa Ito, Mitsuhiro Tsujiwaki, Hiroko Asanuma, Keiko Segawa, Shintaro Sugita
Publikováno v:
Pathology International. 67:510-513
Fluorescence in situ hybridization (FISH) is an essential tool for genetic diagnosis in daily pathological work. Almost full automation of FISH can be achieved with the recently released automated SureFISH platform (Dako Omnis, Agilent Technologies,
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::1fb79020b72c1e3e8c82e4ee644e1e0c
https://doi.org/10.1111/pin.12562
https://doi.org/10.1111/pin.12562
Publikováno v:
Toxicology. 381:19-30
We have reported that excessive nitric oxide (NO), like other reactive oxygen species (ROS), causes a decrease in cytochrome c oxidase (CCO) activity and ATP levels (mitochondrial damage) resulting in lens opacity. In addition, previous reports have
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d3b96d7a53ca4580d5cc17bdd992f912
https://doi.org/10.1016/j.tox.2017.02.014
https://doi.org/10.1016/j.tox.2017.02.014
Publikováno v:
Biological & Pharmaceutical Bulletin. 40:910-915
In a study to find ways to prevent the side effects of indomethacin (IMC), we previously reported that magnesium ion (Mg2+) can prevent the onset of IMC-induced gastric mucosa in adjuvant-induced arthritis (AA) rats, a model for rheumatoid arthritis
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e2068468346ac598d4929a377c48f207
https://doi.org/10.1248/bpb.b17-00151
https://doi.org/10.1248/bpb.b17-00151