Zobrazeno 1 - 10
of 93
pro vyhledávání: '"Yoshikuni Nagamine"'
Autor:
Xiaona Chen, Jie Yuan, Guang Xue, Silvia Campanario, Di Wang, Wen Wang, Xi Mou, Shiau Wei Liew, Mubarak Ishaq Umar, Joan Isern, Yu Zhao, Liangqiang He, Yuying Li, Christopher J. Mann, Xiaohua Yu, Lei Wang, Eusebio Perdiguero, Wei Chen, Yuanchao Xue, Yoshikuni Nagamine, Chun Kit Kwok, Hao Sun, Pura Muñoz-Cánoves, Huating Wang
Publikováno v:
Nature Communications, Vol 12, Iss 1, Pp 1-22 (2021)
Skeletal muscle stem cells (or satellite cells, SCs) are normally quiescent but activate and expand in response to injury. Here the authors show that induction of DHX36 helicase during SC activation promotes mRNA translation by binding to 5′UTR mRN
Externí odkaz:
https://doaj.org/article/6dfdbd5e24c94a98ae8d2a286fba0f68
Autor:
Junwei Nie, Mingyang Jiang, Xiaotian Zhang, Hao Tang, Hengwei Jin, Xinyi Huang, Baiyin Yuan, Chenxi Zhang, Janice Ching Lai, Yoshikuni Nagamine, Dejing Pan, Wengong Wang, Zhongzhou Yang
Publikováno v:
Cell Reports, Vol 13, Iss 4, Pp 723-732 (2015)
RNA G-quadruplexes (G4s) play important roles in RNA biology. However, the function and regulation of mRNA G-quadruplexes in embryonic development remain elusive. Previously, we identified RHAU (DHX36, G4R1) as an RNA helicase that resolves mRNA G-qu
Externí odkaz:
https://doaj.org/article/5aeeba5bedf644c2afdc0913d8208f56
Autor:
Ji-Seung Yoo, Kiyohiro Takahasi, Chen Seng Ng, Ryota Ouda, Koji Onomoto, Mitsutoshi Yoneyama, Janice Ching Lai, Simon Lattmann, Yoshikuni Nagamine, Tadashi Matsui, Kuniyoshi Iwabuchi, Hiroki Kato, Takashi Fujita
Publikováno v:
PLoS Pathogens, Vol 10, Iss 3, p e1004012 (2014)
RIG-I is a DExD/H-box RNA helicase and functions as a critical cytoplasmic sensor for RNA viruses to initiate antiviral interferon (IFN) responses. Here we demonstrate that another DExD/H-box RNA helicase DHX36 is a key molecule for RIG-I signaling b
Externí odkaz:
https://doaj.org/article/4ea6becc61ad46e98744b4fd2a946be6
Autor:
Huating Wang, Wen Wang, Silvia Campanario Sanz, Lei Wang, Xi Mou, Mubarak I. Umar, Hao Sun, Xiaona Chen, Christopher J. Mann, Jie Yuan, Wei Chen, Yuying Li, Guang Xue, Joan Isern, Xiaohua Yu, Yu Zhao, Yuanchao Xue, Pura Muñoz-Cánoves, Chun-Kit Kwok, Di Wang, Liangqiang He, Eusebio Perdiguero, Yoshikuni Nagamine
Skeletal muscle has a remarkable ability to regenerate owing to its resident stem cells, also called satellite cells (SCs), that are normally quiescent. When stimulated by damage, SCs activate and expand to form new fibers. The mechanisms underlying
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::b4befc2f17155a8b8c0f77131bd101da
https://doi.org/10.1101/2020.08.30.274068
https://doi.org/10.1101/2020.08.30.274068
Autor:
Weiwei Huang, Kristin Stadelman, Meimei Wan, Paul Cao, Qiang Zhang, Banabihari Giri, Yoshikuni Nagamine, James P. Vaughn, Lance D. Miller, Guangchao Sui, Ming Lei, Philip J. Smaldino, Steven A. Akman
Publikováno v:
Nucleic Acids Research
Yin Yang 1 (YY1) is a multifunctional protein with regulatory potential in tumorigenesis. Ample studies demonstrated the activities of YY1 in regulating gene expression and mediating differential protein modifications. However, the mechanisms underly
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1b703e3a260e892bb1c3059e9bc255db
http://doc.rero.ch/record/293139/files/gkr849.pdf
http://doc.rero.ch/record/293139/files/gkr849.pdf
Publikováno v:
Nucleic Acids Research
Guanine-quadruplexes (G4) consist of non-canonical four-stranded helical arrangements of guanine-rich nucleic acid sequences. The bulky and thermodynamically stable features of G4 structures have been shown in many respects to affect normal nucleic a
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::af1b4a06d30660f5bdd8c87022a520fe
http://doc.rero.ch/record/292612/files/gkr630.pdf
http://doc.rero.ch/record/292612/files/gkr630.pdf
Autor:
Simon Lattmann, Eric D. Routh, Steven A. Akman, Ryan G. Thys, James P. Vaughn, Banabihari Giri, Roy R. Hantgan, Steven D. Creacy, Philip J. Smaldino, Yoshikuni Nagamine
Publikováno v:
Nucleic Acids Research
It has been previously shown that the DHX36 gene product, G4R1/RHAU, tightly binds tetramolecular G4-DNA with high affinity and resolves these structures into single strands. Here, we test the ability of G4R1/RHAU to bind and unwind unimolecular G4-D
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2c2a62d3e7a91b06e87a8fdd0a1de863
http://doc.rero.ch/record/291105/files/gkr234.pdf
http://doc.rero.ch/record/291105/files/gkr234.pdf
Autor:
Hubertus Kohler, Radek C. Skoda, Patrick Matthias, Dejing Pan, Yoshikuni Nagamine, Janice Ching Lai, Svetlana Ponti
Publikováno v:
Blood
The DEAH helicase RHAU (alias DHX36, G4R1) is the only helicase shown to have G-quadruplex (G4)–RNA resolvase activity and the major source of G4-DNA resolvase activity. Previous report showed RHAU mRNA expression to be elevated in human lymphoid a
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::58dde03ec8e45221a47163837f2d65e5
Publikováno v:
Cancer Letters. 297:165-170
The extracellular signal-regulated kinase (ERK) has been shown to mediate cisplatin (CP)-induced toxicity to renal proximal tubule cells. Here, we demonstrate that ERK serves as the kinase that phosphorylates the pro-apoptotic p66shc protein at its S
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::7c7c678202229ebff802ea6e9cac306f
https://doi.org/10.1016/j.canlet.2010.05.007
https://doi.org/10.1016/j.canlet.2010.05.007
Autor:
Istvan Arany, Trinity Vera, Jeb S. Clark, Radhakrishna Baliga, Yoshikuni Nagamine, Amir Faisal
Publikováno v:
American Journal of Physiology-Renal Physiology. 298:F1214-F1221
Mitochondrial dysfunction is involved in pathopysiology of ischemia-reperfusion-induced acute kidney injury (AKI). The p66shc adaptor protein is a newly recognized mediator of mitochondrial dysfunction, which might play a role in AKI-induced renal tu
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b964156405f63869607abaa67eb69993
https://doi.org/10.1152/ajprenal.00639.2009
https://doi.org/10.1152/ajprenal.00639.2009