Zobrazeno 1 - 10
of 68
pro vyhledávání: '"Yoshiko Takeuchi"'
Autor:
Thomas Thisted, F. Donelson Smith, Arnab Mukherjee, Yuliya Kleschenko, Feng Feng, Zhi-Gang Jiang, Timothy Eitas, Kanam Malhotra, Zuzana Biesova, Adejumoke Onumajuru, Faith Finley, Anokhi Cifuentes, Guolin Zhang, Gaëlle H. Martin, Yoshiko Takeuchi, Kader Thiam, Robert D. Schreiber, Edward H. van der Horst
Publikováno v:
Nature Communications, Vol 15, Iss 1, Pp 1-16 (2024)
Abstract VISTA, an inhibitory myeloid-T-cell checkpoint, holds promise as a target for cancer immunotherapy. However, its effective targeting has been impeded by issues such as rapid clearance and cytokine release syndrome observed with previous VIST
Externí odkaz:
https://doaj.org/article/5baa81963d6e484cb872b3eac39edd59
Autor:
Naveen Sharma, James Allison, Andres Salazar, Hussein Sultan, Ton Schumacher, Ivana Djuretic, Yik Andy Yeung, Jeffrey Ward, Marco Colonna, Yuang Song, Samuel Ameh, Robert Schreiber, Kenneth Murphy, Yoshiko Takeuchi, Corazon Arthur, Kathleen Sheehan, Kelly D Moynihan, Vladimir Sukhov, Maria Firulyova, Tian-Tian Liu, Maxim Artyomov
Publikováno v:
Journal for ImmunoTherapy of Cancer, Vol 11, Iss Suppl 1 (2023)
Externí odkaz:
https://doaj.org/article/644e4169fe854128912cee96e977b9ca
Autor:
Takashi Osamura, Yoshiko Takeuchi, Risako Onodera, Masahiro Kitamura, Yoshiteru Takahashi, Kohei Tahara, Hirofumi Takeuchi
Publikováno v:
Asian Journal of Pharmaceutical Sciences, Vol 13, Iss 2, Pp 113-119 (2018)
We previously determined “Tableting properties” by using a multi-functional single-punch tablet press (GTP-1). We plotted “Compactability” on the x-axis against “Manufacturability” on the y-axis to allow visual evaluation of “Tableting
Externí odkaz:
https://doaj.org/article/226c32c33d734a72b3759eb270bb1095
Autor:
Takashi Osamura, Yoshiko Takeuchi, Risako Onodera, Masahiro Kitamura, Yoshiteru Takahashi, Kohei Tahara, Hirofumi Takeuchi
Publikováno v:
Asian Journal of Pharmaceutical Sciences, Vol 12, Iss 5, Pp 412-417 (2017)
We previously determined “Tableting properties” by using a multi-functional single-punch tablet press (GTP-1). We proposed plotting “Compactability” on the x-axis against “Manufacturability” on the y-axis to allow visual evaluation of “
Externí odkaz:
https://doaj.org/article/08a66f5ccc864c8199979b3eb89dac0d
Autor:
Chika Fujii, Gue Su Chang, Saravanan Raju, Chun Chou, Yoshiko Takeuchi, Elena Tonc, Masahiro Iwamoto, Melanie Holmgren, Yu Xia, Takeshi Egawa
Publikováno v:
Blood
The proliferative burst of B lymphocytes is essential for antigen receptor repertoire diversification during the development and selective expansion of antigen-specific clones during immune responses. High proliferative activity inevitably promotes o
Autor:
Yoshiko Takeuchi, Corazon Arthur, Heather Kohlmiller, James White, Betty Lee, Bin Fan, Jiawei Huang, James Sissons, Jonathan Sitrin, Lee Rivera, Robert Schreiber
Publikováno v:
Regular and Young Investigator Award Abstracts.
Autor:
Kohei Shitara, Akihito Kawazoe, Hitomi Nishinakamura, Shogo Kumagai, Shigeyuki Matsui, Ayaka Tsuge, Naoya Yamazaki, Toshihide Ueno, Kota Itahashi, Shota Fukuoka, Kochin Vitaly, Genichiro Ishii, Takeshi Kuwata, Toshihiko Doi, Yamashita Yasuho, Hiroyuki Mano, Takuma Shibahara, Koichi Goto, Yoshiko Takeuchi, Kenta Nakama, Hiroyoshi Nishikawa, Eri Sugiyama, Hibiki Udagawa, Keisuke Kirita, Masahito Kawazu, Yuka Maeda, Takuma Irie, Takahiro Kamada, Keiju Aokage, Masahiro Tsuboi, Yosuke Togashi
Publikováno v:
Cell Mol Immunol
Immune checkpoint blockade has provided a paradigm shift in cancer therapy, but the success of this approach is very variable; therefore, biomarkers predictive of clinical efficacy are urgently required. Here, we show that the frequency of PD-1+CD8+
Publikováno v:
International Journal of Pharmaceutics. 553:281-289
In the design of the orally disintegrating films (ODFs), it is important to determine the disintegration time (DT) precisely and properly. These films' DTs are usually assessed by a disintegration test defined in the pharmacopoeias, but under the con
Publikováno v:
International journal of pharmaceutics. 586
The control of residence time in a powder mixing process was investigated toward the development of a continuous pharmaceutical manufacturing system. A powder mixer equipped with an impeller and a scraper, which was designed for a continuous granulat
Autor:
Yasuko Tada, Meinoshin Okumura, Yoshiko Takeuchi, Genichiro Ishii, Koichi Goto, Masahiro Tsuboi, Yosuke Togashi, Yasushi Shintani, Shinya Sayoko, Keisuke Kataoka, Hiroyoshi Nishikawa, Eiichi Sato, Kenta Tane, Eri Sugiyama
Publikováno v:
Science Immunology. 5
The clinical efficacy of anti–PD-1 (programmed cell death–1) monoclonal antibody (mAb) against cancers with oncogenic driver gene mutations, which often harbor a low tumor mutation burden, is variable, suggesting different contributions of each d