Zobrazeno 1 - 10
of 21
pro vyhledávání: '"Yoshiko Takeda-Uchimura"'
Autor:
Yoshiko Takeda-Uchimura, Midori Ikezaki, Tomoya O. Akama, Yoshito Ihara, Fabrice Allain, Kazuchika Nishitsuji, Kenji Uchimura
Publikováno v:
Molecules, Vol 29, Iss 4, p 764 (2024)
We recently showed that 6-sulfo sialyl N-acetyllactosamine (LacNAc) in O-linked glycans recognized by the CL40 antibody is abundant in the pleural mesothelium under physiological conditions and that these glycans undergo complementary synthesis by Gl
Externí odkaz:
https://doaj.org/article/a05ca7c0095a482fa2f489acc5395c87
Autor:
Yoshiko Takeda-Uchimura, Kazuchika Nishitsuji, Midori Ikezaki, Tomoya O. Akama, Yoshito Ihara, Fabrice Allain, Kenji Uchimura
Publikováno v:
Frontiers in Neuroanatomy, Vol 16 (2022)
Keratan sulfate (KS) glycan is covalently attached to a core protein of proteoglycans. KS is abundant in neuropils and presents densely in close proximity to the perineuronal region of the perineuronal net-positive neurons in the adult brain under ph
Externí odkaz:
https://doaj.org/article/214dfb5ce4f74815a00a5f1480ead8eb
Autor:
Yoshiko Takeda-Uchimura, Midori Ikezaki, Tomoya O. Akama, Kaho Nishioka, Yoshito Ihara, Fabrice Allain, Kazuchika Nishitsuji, Kenji Uchimura
Publikováno v:
Molecules, Vol 27, Iss 14, p 4543 (2022)
Sialyl 6-sulfo Lewis X (6-sulfo sLeX) and its derivative sialyl 6-sulfo N-acetyllactosamine (LacNAc) are sialylated and sulfated glycans of sialomucins found in the high endothelial venules (HEVs) of secondary lymphoid organs. A component of 6-sulfo
Externí odkaz:
https://doaj.org/article/dd9704c8613a46828188e078636ed947
Autor:
Yoshiko, Takeda-Uchimura, Kazuchika, Nishitsuji, Midori, Ikezaki, Tomoya O, Akama, Yoshito, Ihara, Fabrice, Allain, Kenji, Uchimura
Publikováno v:
Frontiers in neuroanatomy. 16
Keratan sulfate (KS) glycan is covalently attached to a core protein of proteoglycans. KS is abundant in neuropils and presents densely in close proximity to the perineuronal region of the perineuronal net-positive neurons in the adult brain under ph
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::57497cd4cf8de3a306981fc4f53ff7c8
https://pubmed.ncbi.nlm.nih.gov/35221933
https://pubmed.ncbi.nlm.nih.gov/35221933
Publikováno v:
Behavioural Pharmacology. 29:261-269
An extract of rabbit skin inflamed by inoculation with the vaccinia virus, neurotropin [by intravenous, oral, and intramuscular (i.m.) administration], has been used in China and Japan for the treatment of chronic pain. In this study, we investigated
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::59a06eda1c03a29293c7c90d959375e6
https://doi.org/10.1097/fbp.0000000000000313
https://doi.org/10.1097/fbp.0000000000000313
Autor:
Kenji Uchimura, Narentuya, Yoshiko Takeda-Uchimura, Tomoya O. Akama, Kenji Kadomatsu, Zui Zhang, Tahmina Foyez, Yukio Komatsu, Hirokazu Yagi, Koichi Kato
Publikováno v:
Scientific Reports
Scientific Reports, Nature Publishing Group, 2019, 9 (1), ⟨10.1038/s41598-019-40901-2⟩
Scientific Reports, Vol 9, Iss 1, Pp 1-11 (2019)
Scientific Reports, 2019, 9 (1), ⟨10.1038/s41598-019-40901-2⟩
Scientific Reports, Nature Publishing Group, 2019, 9 (1), ⟨10.1038/s41598-019-40901-2⟩
Scientific Reports, Vol 9, Iss 1, Pp 1-11 (2019)
Scientific Reports, 2019, 9 (1), ⟨10.1038/s41598-019-40901-2⟩
Keratan sulfate (KS) is a carbohydrate side chain covalently attached to extracellular proteoglycans. KS is composed of disaccharide units of 6-sulfated N-acetylglucosamine (GlcNAc) and galactose. We have previously shown that GlcNAc-6-O-sulfotransfe
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::223844a5f87dd1e8f1a9d827bdd33585
http://europepmc.org/articles/PMC6416290
http://europepmc.org/articles/PMC6416290
Autor:
Wen Jiang, Yugo Ishino, Takeshi Yoshimura, Kazuhiro Ikenaka, Kenji Kadomatsu, Yoshiko Takeda-Uchimura, Hirokazu Hashimoto, Kenji Uchimura
Publikováno v:
Neurochemical Research. 41:450-462
Keratan sulfate (KS) is a sulfated glycosaminoglycan and has been shown to bind to sonic hedgehog (Shh), which act as a morphogen to regulate the embryonic spinal cord development. We found highly sulfated KS was present in the floor plate (including
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b1a70eef645f712f3f54bd3a1b75c533
https://doi.org/10.1007/s11064-016-1861-9
https://doi.org/10.1007/s11064-016-1861-9
Autor:
Kenji Kadomatsu, Kenji Uchimura, Yoshiko Takeda-Uchimura, Narentuya, Zui Zhang, Gen Sobue, Tahmina Foyez, Shinsuke Ishigaki
Publikováno v:
The American Journal of Pathology. 185:3053-3065
The functional role of 5D4 antibody-reactive keratan sulfate (KS) in the pathogenesis of neurodegenerative diseases is unknown. We therefore studied the expression of 5D4-reactive KS in amyotrophic lateral sclerosis (ALS), a motor neuron-degenerative
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2e18ff9063651b4ce778c2da7252c417
https://doi.org/10.1016/j.ajpath.2015.07.016
https://doi.org/10.1016/j.ajpath.2015.07.016
Autor:
Makoto Michikawa, Shiori Ohtake-Niimi, Yoshiko Takeda-Uchimura, Kenji Uchimura, Hitomi Hoshino, Kenji Kadomatsu, Tahmina Foyez
Publikováno v:
Journal of Histochemistry & Cytochemistry. 62:145-156
Keratan sulfate (KS) comprises repeating disaccharides of galactose (Gal) and N-acetylglucosamine (GlcNAc). Residues of Gal and GlcNAc in KS are potentially modified with sulfate at their C-6 positions. The 5D4 monoclonal antibody recognizes KS struc
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::9176a4de9f0c75597d5e0f9340266161
https://doi.org/10.1369/0022155413511619
https://doi.org/10.1369/0022155413511619
Autor:
Jared R. Tinklenberg, D. Larry Sparks, Jeffrey Kaye, Lennart Minthon, Adam L. Boxer, Jerzy Leszek, Charles Herbert, Anna Karydas, Douglas Galasko, Marwan N. Sabbagh, Gil D. Rabinovici, Massimo Tabaton, Joseph F. Quinn, Bruce L. Miller, Markus Britschgi, Leah Friedman, Kaj Blennow, William H. Robinson, Jerome A. Yesavage, Tony Wyss-Coray, Robert Tibshirani, Yoshiko Takeda-Uchimura, Sandip Ray, Marek Jutel, Yuen T. So
Publikováno v:
Nature Medicine. 13:1359-1362
A molecular test for Alzheimer's disease could lead to better treatment and therapies. We found 18 signaling proteins in blood plasma that can be used to classify blinded samples from Alzheimer's and control subjects with close to 90% accuracy and to
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ec489ab8221c57cec77f901fe5eff1db
https://doi.org/10.1038/nm1653
https://doi.org/10.1038/nm1653