Zobrazeno 1 - 10
of 29
pro vyhledávání: '"Yoshiko Nakada"'
Autor:
Hisano Yajima, Yuki Anraku, Yu Kaku, Kanako Terakado Kimura, Arnon Plianchaisuk, Kaho Okumura, Yoshiko Nakada-Nakura, Yusuke Atarashi, Takuya Hemmi, Daisuke Kuroda, Yoshimasa Takahashi, Shunsuke Kita, Jiei Sasaki, Hiromi Sumita, The Genotype to Phenotype Japan (G2P-Japan) Consortium, Jumpei Ito, Katsumi Maenaka, Kei Sato, Takao Hashiguchi
Publikováno v:
Nature Communications, Vol 15, Iss 1, Pp 1-14 (2024)
Abstract Since 2019, SARS-CoV-2 has undergone mutations, resulting in pandemic and epidemic waves. The SARS-CoV-2 spike protein, crucial for cellular entry, binds to the ACE2 receptor exclusively when its receptor-binding domain (RBD) adopts the up-c
Externí odkaz:
https://doaj.org/article/8f72f42029744654960e7c16b705eb3b
Autor:
Rie Umeda, Yuhkoh Satouh, Mizuki Takemoto, Yoshiko Nakada-Nakura, Kehong Liu, Takeshi Yokoyama, Mikako Shirouzu, So Iwata, Norimichi Nomura, Ken Sato, Masahito Ikawa, Tomohiro Nishizawa, Osamu Nureki
Publikováno v:
Nature Communications, Vol 11, Iss 1, Pp 1-11 (2020)
Tetraspanins play critical roles in various physiological processes, ranging from cell adhesion to virus infection. Here authors report the crystal structure of CD9 and the cryo-electron microscopic structure of CD9 in complex with its single membran
Externí odkaz:
https://doaj.org/article/aecd1e2237844613810328e87f0dcce7
Autor:
Fei Jin, Minxuan Sun, Takashi Fujii, Yurika Yamada, Jin Wang, Andrés D Maturana, Miki Wada, Shichen Su, Jinbiao Ma, Hironori Takeda, Tsukasa Kusakizako, Atsuhiro Tomita, Yoshiko Nakada-Nakura, Kehong Liu, Tomoko Uemura, Yayoi Nomura, Norimichi Nomura, Koichi Ito, Osamu Nureki, Keiichi Namba, So Iwata, Ye Yu, Motoyuki Hattori
Publikováno v:
PLoS Biology, Vol 19, Iss 4, p e3001231 (2021)
MgtE is a Mg2+ channel conserved in organisms ranging from prokaryotes to eukaryotes, including humans, and plays an important role in Mg2+ homeostasis. The previously determined MgtE structures in the Mg2+-bound, closed-state, and structure-based fu
Externí odkaz:
https://doaj.org/article/1ea7be941cf6441f841a041603748098
Publikováno v:
Biochemistry and Biophysics Reports, Vol 24, Iss , Pp 100850- (2020)
Angiotensin II (Ang II) type 2 receptor (AT2R) is one of the major components of the renin-angiotensin-aldosterone system. Nevertheless, the physiological role is not well defined compared to the understanding of the Ang II type 1 receptor (AT1R), wh
Externí odkaz:
https://doaj.org/article/49d46f3fbaa64f5cba08ea68919ac2b1
Autor:
Kumar Nagarathinam, Yoshiko Nakada-Nakura, Christoph Parthier, Tohru Terada, Narinobu Juge, Frank Jaenecke, Kehong Liu, Yunhon Hotta, Takaaki Miyaji, Hiroshi Omote, So Iwata, Norimichi Nomura, Milton T. Stubbs, Mikio Tanabe
Publikováno v:
Nature Communications, Vol 9, Iss 1, Pp 1-9 (2018)
The multidrug resistance transporter mediated efflux of antibiotics from the bacterial cytoplasm represents a major challenge to medicine. Here authors solve the X-ray crystallographic structure of the drug/H+ antiporter MdfA from Escherichia coli an
Externí odkaz:
https://doaj.org/article/9c31b685bee4442382a7b84e7402aa22
Autor:
Go Kasuya, Yuichiro Fujiwara, Mizuki Takemoto, Naoshi Dohmae, Yoshiko Nakada-Nakura, Ryuichiro Ishitani, Motoyuki Hattori, Osamu Nureki
Publikováno v:
Cell Reports, Vol 14, Iss 4, Pp 932-944 (2016)
P2X receptors are trimeric ATP-gated cation channels involved in physiological processes ranging widely from neurotransmission to pain and taste signal transduction. The modulation of the channel gating, including that by divalent cations, contribute
Externí odkaz:
https://doaj.org/article/cda8bfce19f5423cb60ffb4b68cd0d7d
Autor:
Takeshi Yokoyama, Tomohiro Nishizawa, Kehong Liu, Rie Umeda, So Iwata, Yuhkoh Satouh, Osamu Nureki, Norimichi Nomura, Ken Sato, Yoshiko Nakada-Nakura, Masahito Ikawa, Mikako Shirouzu, Mizuki Takemoto
Publikováno v:
Nature Communications, Vol 11, Iss 1, Pp 1-11 (2020)
Nature Communications
Nature Communications
Umeda, R., Satouh, Y., Takemoto, M. et al. Structural insights into tetraspanin CD9 function. Nat Commun 11, 1606 (2020). https://doi.org/10.1038/s41467-020-15459-7
Tetraspanins play critical roles in various physiological processes, ranging fro
Tetraspanins play critical roles in various physiological processes, ranging fro
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::deceece91012b93efb7188f8e4f119a6
https://doaj.org/article/aecd1e2237844613810328e87f0dcce7
https://doaj.org/article/aecd1e2237844613810328e87f0dcce7
Publikováno v:
Biochemistry and Biophysics Reports, Vol 24, Iss, Pp 100850-(2020)
Biochemistry and Biophysics Reports
Biochemistry and Biophysics Reports
Angiotensin II (Ang II) type 2 receptor (AT2R) is one of the major components of the renin-angiotensin-aldosterone system. Nevertheless, the physiological role is not well defined compared to the understanding of the Ang II type 1 receptor (AT1R), wh
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::cad6eada6e6dca29844ad6ce5269b984
http://www.sciencedirect.com/science/article/pii/S2405580820301606
http://www.sciencedirect.com/science/article/pii/S2405580820301606
Autor:
Takashi Fujii, Miki Wada, Jun-Song Wang, Yayoi Nomura, Andrés D. Maturana, Tsukasa Kusakizako, Yurika Yamada, So Iwata, Osamu Nureki, Yoshiko Nakada-Nakura, Atsuhiro Tomita, Motoyuki Hattori, Jie Ma, Keiichi Namba, Kei K. Ito, Minxuan Sun, H. Takeda, Fei Jin, Tomoko Uemura, Shichen Su, Norimichi Nomura, Ye Yu, Kehong Liu
MgtE is a Mg2+ channel conserved in organisms ranging from prokaryotes to eukaryotes, including humans, and plays an important role in Mg2+ homeostasis. The previously determined MgtE structures in the Mg2+-bound, closed state and structure-based fun
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::cee246f6a6872896253039229e7be2e3
https://doi.org/10.1101/2020.08.27.270991
https://doi.org/10.1101/2020.08.27.270991
Autor:
Keitaro Yamashita, Junken Aoki, Yoshiko Nakada-Nakura, Osamu Nureki, Misa Sayama, Takayuki Doi, Yoshiki Tanaka, Akiharu Uwamizu, Reiya Taniguchi, Masahito Yoshida, Kunio Hirata, Tomohiko Ohwada, Tomohiro Nishizawa, Asuka Inoue, Ryuichiro Ishitani, Hideaki E. Kato, Yuko Otani
Publikováno v:
Nature. 548:356-360
Determination of the crystal structure of the zebrafish LPA6 receptor shows that the lipid ligand binds to an unusual ligand-binding pocket in the receptor that is laterally accessible through the membrane. The lysophosphatidic acid (LPA) receptors a
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::4ad5005bc190e2f8215236570b11e87b
https://doi.org/10.1038/nature23448
https://doi.org/10.1038/nature23448