Zobrazeno 1 - 10
of 20
pro vyhledávání: '"Yoshiko Kaku"'
Publikováno v:
Journal of Pharmacological Sciences, Vol 129, Iss 3, Pp 160-168 (2015)
1,2-Diarachidonoyl-sn-glycero-3-phosphoethanolamine (DAPE) induces both necrosis/necroptosis and apoptosis of NCI-H28 malignant pleural mesothelioma (MPM) cells. The present study was conducted to understand the mechanism for DAPE-induced apoptosis o
Externí odkaz:
https://doaj.org/article/e34828818a2d46f7b5d2150db08ec0f7
Autor:
Tomoyuki Nishizaki, Takeshi Kanno, Ayako Tsuchiya, Yoshiko Kaku, Tadashi Shimizu, Akito Tanaka
Publikováno v:
Molecules, Vol 19, Iss 12, Pp 21462-21472 (2014)
We have originally synthesized the naftopidil analogue 1-[2-(2-methoxyphenylamino)ethylamino]-3-(naphthalene-1-yloxy)propan-2-ol (HUHS 1015) as a new anticancer drug. HUHS1015 induces cell death in a wide variety of human cancer cell lines originated
Externí odkaz:
https://doaj.org/article/ea716664b1dc4192bc0046a5ba580dc5
Publikováno v:
Anti-Cancer Agents in Medicinal Chemistry. 15:242-247
The newly synthesized naftopidil analogue HUHS1015 reduced viability of MKN28 and MKN45 human gastric cancer cells in a concentration (0.3-100 μM)-dependent manner, with the potential greater than that for naftopidil. In the cell cycle analysis, HUH
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::88404ba29c9cb51460a28a7b25b28593
https://doi.org/10.2174/1871520614666140922122700
https://doi.org/10.2174/1871520614666140922122700
Autor:
Yoshiko Kaku, Tomoyuki Nishizaki, Takeshi Kanno, Ayako Tsuchiya, Akito Tanaka, Tadashi Shimizu
Publikováno v:
Molecules
Molecules, Vol 19, Iss 12, Pp 21462-21472 (2014)
Molecules, Vol 19, Iss 12, Pp 21462-21472 (2014)
We have originally synthesized the naftopidil analogue 1-[2-(2-methoxyphenylamino)ethylamino]-3-(naphthalene-1-yloxy)propan-2-ol (HUHS 1015) as a new anticancer drug. HUHS1015 induces cell death in a wide variety of human cancer cell lines originated
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::af4196fae6974f649f1837d338d896a0
https://doi.org/10.3390/molecules191221462
https://doi.org/10.3390/molecules191221462
Autor:
Takeshi Kanno, Yoshiko Kaku, Akito Tanaka, Akinobu Gotoh, Tomoyuki Nishizaki, Tadashi Shimizu, Hisao Nagaya, Ayako Tsuchiya, Takashi Nakano, Syuhei Nakao, Chiharu Tabata
Publikováno v:
Cancer Science
The newly synthesized naftopidil analogue HUHS1015 reduced cell viability in malignant pleural mesothelioma cell lines MSTO-211H, NCI-H28, NCI-H2052, and NCI-H2452, with the potential greater than that for the anticancer drugs paclitaxel or cisplatin
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b9cfd23e08e2d97a0a16d59295621a0b
https://doi.org/10.1111/cas.12429
https://doi.org/10.1111/cas.12429
Autor:
Masaaki Mitsutsuji, Tomoko Tanaka, Etsuji Shimada, Yoshiko Kaku, Takeshi Iwasaki, Masayuki Fujita
Publikováno v:
Nippon Daicho Komonbyo Gakkai Zasshi. 67:402-407
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::d413164fffb491ea6fed0dfef8a8a05b
https://doi.org/10.3862/jcoloproctology.67.402
https://doi.org/10.3862/jcoloproctology.67.402
Publikováno v:
Anticancer research. 36(1)
The newly-synthesized naftopidil analog HUHS1015 suppresses tumor growth and induces apoptosis of cells from a variety of cancer types. The present study was conduced to assess the effect of HUHS1015 on human colonic cancer cells and to clarify the u
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::4d9e6d00a467a2329fa48df76956199a
https://pubmed.ncbi.nlm.nih.gov/26722026
https://pubmed.ncbi.nlm.nih.gov/26722026
Autor:
Masato, Ohyama, Ayako, Tsuchiya, Yoshiko, Kaku, Takeshi, Kanno, Tadashi, Shimizu, Akito, Tanaka, Tomoyuki, Nishizaki
Publikováno v:
Anticancer research. 35(12)
The present study investigated the mechanism underlying the apoptosis of MKN28 human gastric cancer cells induced by the phosphatidylinositol (PI) derivative 1,2-O-bis-[8-{2-(2-pentyl-cyclopropylmethyl)-cyclopropyl}-octanoyl]-sn-glycero-3-phosphatidy
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::10ae94e67df3911d1608bd8b3ca073a3
https://pubmed.ncbi.nlm.nih.gov/26637870
https://pubmed.ncbi.nlm.nih.gov/26637870
Autor:
Yoshiko Kaku, Hiroyuki Suzuki, Tatsuo Sumino, Kazuichi Isaka, Masayuki Ohta, Takahide Yokoi, Hajime Ikuta, Masako Wagatsuma
Publikováno v:
FEMS Microbiology Letters. 273:166-171
To investigate uncharacterized microbial communities, a custom DNA microarray named ‘FloraArray’ was developed for screening specific probes that would represent the characteristics of a microbial community. The array was prepared by spotting 200
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::86c50ba485628c0784831c621c99a42f
https://doi.org/10.1111/j.1574-6968.2007.00799.x
https://doi.org/10.1111/j.1574-6968.2007.00799.x
Autor:
Junji Watari, Takahide Yokoi, Shigehisa Yokoi, Toshio Kurihara, Syunsuke Fukuhara, Masayuki Ohta, Toshiro Saito, Yoshiko Kaku, Masahide Sato, Naoyuki Kobayashi
Publikováno v:
Journal of the American Society of Brewing Chemists. 65:92-98
We used a shotgun DNA microarray strategy for gene expression analysis in brewing lager yeast for the first time. We constructed a random genomic library from a bottom-fermenting (lager) yeast strain, Weihenstephan 34/70, which is widely used in lage
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::42f26820f34dfc984215c3e5e2c4d902
https://doi.org/10.1094/asbcj-2007-0319-02
https://doi.org/10.1094/asbcj-2007-0319-02