Zobrazeno 1 - 10
of 43
pro vyhledávání: '"Yoshiki Tsuboi"'
Autor:
Keisuke Maeda, Ryosuke Fujii, Hiroya Yamada, Eiji Munetsuna, Mirai Yamazaki, Yoshitaka Ando, Genki Mizuno, Hiroaki Ishikawa, Koji Ohashi, Yoshiki Tsuboi, Yuji Hattori, Yuya Ishihara, Nobuyuki Hamajima, Shuji Hashimoto, Koji Suzuki
Publikováno v:
Endocrine Journal, Vol 71, Iss 6, Pp 593-601 (2024)
Thioredoxin-interacting protein (TXNIP) plays an important role in glucose metabolism, and its expression is regulated by DNA methylation (DNAm). Although the association between TXNIP DNAm and type 2 diabetes mellitus has been demonstrated in studie
Externí odkaz:
https://doaj.org/article/c887e932ac4a41ebb7551cade7f5237d
Autor:
Eirin Sakaguchi, Hiroyuki Naruse, Yuya Ishihara, Hidekazu Hattori, Akira Yamada, Hideki Kawai, Takashi Muramatsu, Yoshiki Tsuboi, Ryosuke Fujii, Koji Suzuki, Junnichi Ishii, Kuniaki Saito, Masayoshi Sarai, Masanobu Yanase, Yukio Ozaki, Hideo Izawa
Publikováno v:
Scientific Reports, Vol 14, Iss 1, Pp 1-8 (2024)
Abstract The renal angina index (RAI) is a validated scoring tool for predicting acute kidney injury (AKI). We investigated the efficacy of the RAI in 2436 heterogeneous patients (mean age, 70 years) treated in cardiac intensive care units (CICUs). T
Externí odkaz:
https://doaj.org/article/3a177537cc844c3596af36bbb65d6c4e
Publikováno v:
Epigenetics, Vol 17, Iss 7, Pp 759-785 (2022)
DNA methylation (DNAm) is one of the most studied epigenetic modifications. DNAm has emerged as a key biological mechanism and biomarkers to test associations between environmental exposure and outcomes in epidemiological studies. Although previous s
Externí odkaz:
https://doaj.org/article/40a3a40cd4364538acb0a4037178b563
Autor:
Yoshifumi Noda, Hiroyuki Tomita, Takuma Ishihara, Yoshiki Tsuboi, Nobuyuki Kawai, Masaya Kawaguchi, Tetsuro Kaga, Fuminori Hyodo, Akira Hara, Avinash R. Kambadakone, Masayuki Matsuo
Publikováno v:
BMC Medical Imaging, Vol 22, Iss 1, Pp 1-10 (2022)
Abstract Background To evaluate the utility of histogram analysis (HA) of apparent diffusion coefficient (ADC) values to predict the overall survival (OS) in patients with pancreatic ductal adenocarcinoma (PDAC) and to correlate with pathologically e
Externí odkaz:
https://doaj.org/article/c25b68f4d6c844c8983bbea804baa89b
Autor:
Yuki Nouchi, Eiji Munetsuna, Hiroya Yamada, Mirai Yamazaki, Yoshitaka Ando, Genki Mizuno, Miyuki Ikeya, Itsuki Kageyama, Takuya Wakasugi, Atsushi Teshigawara, Yuji Hattori, Yoshiki Tsuboi, Hiroaki Ishikawa, Koji Suzuki, Koji Ohashi
Publikováno v:
Nutrients, Vol 15, Iss 9, p 2122 (2023)
We previously reported that maternal fructose consumption increases blood corticosterone levels in rat offspring. However, the underlying mechanism of action remains unclear. In the present study, we aimed to elucidate the molecular mechanism by whic
Externí odkaz:
https://doaj.org/article/53a10b7d462c4ce2ae21915d277c1cc1
Autor:
Keisuke Maeda, Hiroya Yamada, Eiji Munetsuna, Ryosuke Fujii, Mirai Yamazaki, Yoshitaka Ando, Genki Mizuno, Hiroaki Ishikawa, Koji Ohashi, Yoshiki Tsuboi, Shuji Hashimoto, Nobuyuki Hamajima, Koji Suzuki
Publikováno v:
PLoS ONE, Vol 15, Iss 7, p e0235486 (2020)
Thioredoxin-interacting protein (TXNIP) inhibits the activity of thioredoxin (TXN), leading to increased oxidative stress. Expression of the TXNIP gene is regulated by DNA methylation. However, no study has reported the influence of lifestyle factors
Externí odkaz:
https://doaj.org/article/614b560c58cd4f3eae73969aeff435aa
Autor:
Ryosuke Fujii, Cristian Pattaro, Yoshiki Tsuboi, Yuya Ishihara, Roberto Melotti, Hiroya Yamada, Yoshitaka Ando, Hiroaki Ishikawa, Koji Ohashi, Shuji Hashimoto, Nobuyuki Hamajima, Giulia Barbieri, Dariush Ghasemi-Semeskandeh, Koji Suzuki
Publikováno v:
Clinical Biochemistry. 111:54-59
Previous studies have proposed different formulas of estimating glomerular filtration rate (eGFR) among clinical patients. The comprehensive comparison of eGFR formulas is not well established in a Japanese population. We compared eGFR values and chr
Autor:
Keisuke Maeda, Hiroya Yamada, Eiji Munetsuna, Ryosuke Fujii, Mirai Yamazaki, Yoshitaka Ando, Genki Mizuno, Hiroaki Ishikawa, Koji Ohashi, Yoshiki Tsuboi, Yuji Hattori, Yuya Ishihara, Shuji Hashimoto, Nobuyuki Hamajima, Koji Suzuki
Publikováno v:
The American Journal of Drug and Alcohol Abuse. 48:302-310
Autor:
Yoshitaka Ando, Nobuyuki Hamajima, Hiroaki Ishikawa, Hiroya Yamada, Eiji Munetsuna, Ryosuke Fujii, Keisuke Maeda, Mirai Yamazaki, Genki Mizuno, Shuji Hashimoto, Koji Suzuki, Yoshiki Tsuboi, Koji Ohashi
Publikováno v:
Endocrine Journal. 69:319-326
Metabolic syndrome (MetS) is cluster of metabolic diseases, including abdominal obesity, hyperglycemia, high blood pressure, and dyslipidemia, that directly escalate the risk of type 2 diabetes, heart disease, and stroke. Thioredoxin-interacting prot
Autor:
Yuji, Hattori, Hiroya, Yamada, Eiji, Munetsuna, Yoshitaka, Ando, Genki, Mizuno, Ryosuke, Fujii, Yoshiki, Tsuboi, Naohiro, Ichino, Keisuke, Osakabe, Keiko, Sugimoto, Hiroaki, Ishikawa, Koji, Ohashi, Koji, Suzuki
Publikováno v:
Endocrine Journal. 69:999-1006
The increasing prevalence of nonalcoholic fatty liver disease (NAFLD) is a global health problem. In recent years, the inhibitory effect of brain-derived neurotrophic factor (BDNF) on diabetes mellitus and fatty liver has been clarified. The purpose