Zobrazeno 1 - 10
of 24
pro vyhledávání: '"Yoshiki Shimatsu"'
Publikováno v:
Experimental Animals
Most cases of ischemic heart disease and stroke occur as a result of atherosclerosis. The purpose of this study was to produce a new Nippon Institute for Biological Science (NIBS) miniature pig model by somatic cell nuclear transfer (SCNT) for studyi
Autor:
Masayuki Tasaki, Hisashi Sahara, M. Sekijima, Kazuhiko Yamada, Akira Shimizu, Vincenzo Villani, S. Waki, Kazuaki Nakano, Hiroshi Nagashima, Yoshiki Shimatsu, Jay A. Fishman, Hitomi Matsunari, Robert A. Wilkinson
Publikováno v:
Transplantation. 98:419-426
BACKGROUND Various durations of survival have been observed in the xenotransplantation of life-supporting α-1,3-galactosyltransferase knockout (GalT-KO) porcine kidneys into nonhuman primates. Although others have demonstrated loss of GalT-KO-transp
Autor:
Ikuya Nonaka, Katsutoshi Yuasa, Nobuyuki Urasawa, Toshiaki Sano, Akinori Nakamura, Michiko R. Wada, Shin'ichi Takeda, Yoshiki Shimatsu, Noboru Machida, Shigeki Yuasa, Yoshito Wakao
Publikováno v:
Circulation. 117:2437-2448
Background— Respiratory support therapy significantly improves life span in patients with Duchenne muscular dystrophy; cardiac-related fatalities, including lethal arrhythmias, then become a crucial issue. It is therefore important to more thorough
Autor:
Masashi Miyake, Masayasu Yamada, Yoshiki Shimatsu, Hiroshi Imai, Yasumitsu Nagao, Masaki Uchida, Naojiro Minami, Yoichiro Hoshino
Publikováno v:
Cloning and Stem Cells. 7:17-26
The developmental competence of domestic pig oocytes that were transferred to somatic cell nuclei of miniature pig was examined. A co-culture system of oocytes with follicle shells was used for the maturation of domestic pig oocytes in vitro. Co-cult
Autor:
Masao Nakura, Shin'ichi Takeda, Masayuki Tomohiro, Yoshikuni Tanioka, Yoshiki Shimatsu, Katsutoshi Yuasa, Joe N. Kornegay, Ikuya Nonaka, Kouichi Katagiri, Toshio Furuta
Publikováno v:
Experimental Animals. 52:93-97
The purpose of this study was to develop a strain of canine X-linked muscular dystrophy (CXMD), a model of Duchenne muscular dystrophy, in Japan. A female beagle was artificially inseminated with frozen-thawed spermatozoa derived from an affected gol
Autor:
Noriko Matsuyama, Yoshiki Shimatsu, Rikio Niki, Masaki Uchida, Kyuichiro Onoe, Hiroshi Imai, Joh-E Ikeda
Publikováno v:
Transgenic Research. 10:577-582
Miniature pig is an attractive animal for a wide range of research fields, such as medicine and pharmacology, because of its small size, the possibility of breeding it under minimum environmental controls and the physiology that is potentially simila
Autor:
Hitoshi Arakawa, Kouichi Katagiri, Yoshiki Shimatsu, Yoji Mamiya, Manabu Tanigawa, Toyokazu Matsuura, Toshio Furuta
Publikováno v:
Journal of Reproduction and Development. 46:315-318
The purpose of this study was to examine fertilities from mating and artificial insemination (AI) with frozen-thawed spermatozoa by indexing the luteinizing hormone (LH) surge with the Canine Ovulation Timing Test (ICG Status-LHTM) in beagle bitches.
Autor:
Tomiji Akita, Yoshiki Shimatsu, Eiji Kobayashi, Rho Yamada, Mitsuru Minezawa, Toshimi Matsumoto, Akira Onishi
Publikováno v:
The Journal of animal genetics. 27:1-6
We analyzed the porcine gene coding for Apolipoprotein B (APOB) to examine variation in the PRE-1 sequence of this gene using DNA samples from 10 pig breeds and populations, and two families. The sequences of the primers were selected from unique seq
Autor:
Atsushi Hirakata, Toshiki Saitoh, Akira Shimizu, Junichi Sano, S. Waki, Kazuhiko Yamada, David H. Sachs, Yoshiki Shimatsu, Wataru Horii, Hisashi Sahara, Tetsuo Nunoya, Hajime Yazawa, Yuji Sakamoto
Publikováno v:
Xenotransplantation.
Background Nuclear transfer (NT) technologies offer a means for producing the genetically modified pigs necessary to develop swine models for mechanistic studies of disease processes as well as to serve as organ donors for xenotransplantation. Most p
Autor:
Akio Takahashi, Naoko Yugeta, Masao Nakura, Nobuyuki Urasawa, Yoshiki Shimatsu, Yoshito Wakao, Akinori Nakamura, Madoka Yoshimura, Masayuki Tomohiro, Noboru Machida, Shin'ichi Takeda, Katsutoshi Yuasa, Yoko Fujii, Michiko R Wada
Publikováno v:
BMC Cardiovascular Disorders
BMC Cardiovascular Disorders, Vol 6, Iss 1, p 47 (2006)
BMC Cardiovascular Disorders, Vol 6, Iss 1, p 47 (2006)
Background Cardiac mortality in Duchenne muscular dystrophy (DMD) has recently become important, because risk of respiratory failure has been reduced due to widespread use of the respirator. The cardiac involvement is characterized by distinctive ele