Zobrazeno 1 - 9
of 9
pro vyhledávání: '"Yoshiki, Satake"'
Autor:
Ryota Nakahigashi, Keigo Matsutani, Takehisa Suzuki, Masaatsu Adachi, Yoshiki Satake, Hideki Abe, Toshio Nishikawa, Yasuhisa Noguchi
Publikováno v:
Scientific reports. 12(1)
Toxic puffers contain the potent neurotoxin, tetrodotoxin (TTX). Although TTX is considered to serve as a defense substance, previous behavioral studies have demonstrated that TTX acts as an attractive pheromone for some toxic puffers. To elucidate t
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::938dd4af40367293063a64e466be5521
https://pubmed.ncbi.nlm.nih.gov/36064732
https://pubmed.ncbi.nlm.nih.gov/36064732
Autor:
Tomoyoshi, Imaizumi, Michinori, Akaiwa, Tomoaki, Abe, Takahiro, Nigawara, Takanori, Koike, Yoshiki, Satake, Kazushi, Watanabe, Osamu, Kaneko, Yasushi, Amano, Kenichi, Mori, Yosuke, Yamanaka, Takeyuki, Nagashima, Masashi, Shimazaki, Kazuyuki, Kuramoto
Publikováno v:
Bioorganic & Medicinal Chemistry. 71:116949
RAS protein plays a key role in cellular proliferation and differentiation. RAS gene mutation is a known driver of oncogenic alternation in human cancer. RAS inhibition is an effective therapeutic treatment for solid tumors, but RAS protein has been
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b8d7da162113fdb0136dd48b51690460
https://doi.org/10.1016/j.bmc.2022.116949
https://doi.org/10.1016/j.bmc.2022.116949
Autor:
Yoshiki Satake, Shouta Tokoro, Takuya Imazu, Yukie Chiba, Yuko Cho, Minoru Wakamori, Mari Yotsu-Yamashita, Toshio Nishikawa, Tadaaki Tsukamoto, Tomoshi Yamada, Ryo Sakakibara, Masaatsu Adachi, Shunsuke Tsunogae, Keiichi Konoki
Publikováno v:
British Journal of Pharmacology. 174:3881-3892
Background and purpose The development of subtype-selective ligands to inhibit voltage-sensitive sodium channels (VSSCs) has been attempted with the aim of developing therapeutic compounds. Tetrodotoxin (TTX) is a toxin from pufferfish that strongly
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::77e240faed41fc52b9d253cd7d1e6754
https://doi.org/10.1111/bph.13985
https://doi.org/10.1111/bph.13985
Publikováno v:
Chemistry Letters. 43:1719-1721
5,6,11-Trideoxytetrodotoxin, a naturally occurring analog of tetrodotoxin, was synthesized from a synthetic intermediate of 5-deoxytetrodotoxin by continuous radical deoxygenation of two hydroxy gr...
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::9595405362c3bc06ff2cd0ac396f9014
https://doi.org/10.1246/cl.140684
https://doi.org/10.1246/cl.140684
Autor:
Minoru Isobe, Yoshiki Satake, Takuya Imazu, Toshio Nishikawa, Masaatsu Adachi, Ryo Sakakibara
Publikováno v:
ChemInform. 45
The first total synthesis of chiriquitoxin, the most structurally complex analogue of tetrodotoxin isolated from a Costa Rican dart frog, has been accomplished from a newly designed intermediate for a variety of tetrodotoxin derivatives. The synthesi
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::cae44cc560e6fec8194336d761a93771
https://doi.org/10.1002/chin.201430216
https://doi.org/10.1002/chin.201430216
Autor:
Yoshiki Satake, Mari Yotsu-Yamashita, Toshio Nishikawa, Minoru Isobe, Shouta Tokoro, Masaatsu Adachi
Publikováno v:
Chemistry, an Asian journal. 9(7)
Tetrodotoxin, a toxic principle of puffer fish intoxication, is one of the most famous marine natural products owing to its complex structure and potent biological activity, which leads to fatal poisoning. Continuous synthetic studies on tetrodotoxin
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2c116d6df40ed559544dace3126653f2
https://pubmed.ncbi.nlm.nih.gov/24861489
https://pubmed.ncbi.nlm.nih.gov/24861489
Autor:
Ryo Sakakibara, Yoshiki Satake, Minoru Isobe, Toshio Nishikawa, Masaatsu Adachi, Takuya Imazu
Publikováno v:
Chemistry (Weinheim an der Bergstrasse, Germany). 20(5)
The first total synthesis of chiriquitoxin, the most structurally complex analogue of tetrodotoxin isolated from a Costa Rican dart frog, has been accomplished from a newly designed intermediate for a variety of tetrodotoxin derivatives. The synthesi
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ef634f34bc623bcf0aa35e3e584f0a75
https://pubmed.ncbi.nlm.nih.gov/24458910
https://pubmed.ncbi.nlm.nih.gov/24458910
Publikováno v:
Masui. The Japanese journal of anesthesiology. 59(4)
Lingual tonsillar hyperplasia is rare, but may cause difficult or impossible tracheal intubation. We administered anesthesia to a female patient with a body mass index (BMI) of 47 kg x m(-2) with unexpected lingual tonsillar hyperplasia. A 32-year-ol
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::c7f26ce1b7303287716531ceb449248d
https://pubmed.ncbi.nlm.nih.gov/20420133
https://pubmed.ncbi.nlm.nih.gov/20420133
Publikováno v:
Chemistry Letters; 11/5/2014, Vol. 43 Issue 11, p1719-1721, 3p