Zobrazeno 1 - 10
of 52
pro vyhledávání: '"Yoshikazu Koyama"'
Autor:
Francesca Amati, Laura Diano, Lucia Vecchione, Giuseppe Danilo Norata, Yoshikazu Koyama, Lucia Cutuli, Alberico Luigi Catapano, Francesco Romeo, Hironori Ando, Giuseppe Novelli
Publikováno v:
Molecular Therapy: Nucleic Acids, Vol 1, Iss C (2012)
Externí odkaz:
https://doaj.org/article/57701d2887434048a0599962c864d030
Autor:
Atsushi Watanabe, Kazuhiro Kawai, Eiji Hata, Shinya Goto, Yasunori Shinozuka, Tomomi Kurumisawa, Yoshikazu Koyama, Yukio Chikayama, Yoshio Kiku, Yuya Nagasawa, Tomohito Hayashi
Publikováno v:
Japanese Journal of Veterinary Research; 2021, Vol. 69 Issue 4, p195-203, 9p
Autor:
Hiroshi Shimizu, Mikako Sasaki, Yasuyuki Fujita, Naoya Yoshioka, Tsutomu Hirasawa, Tadamichi Shimizu, Daichi Hoshina, Lin Leng, Shigeki Ohshima, Jun Nishihira, Riichiro Abe, Shin Onodera, Yoshikazu Koyama, Richard Bucala, Asuka Hamasaka
Publikováno v:
Journal of Allergy and Clinical Immunology. 124:90-99
Background Atopic dermatitis (AD) is a common chronic inflammatory skin disease. Macrophage migration inhibitory factor (MIF) is a proinflammatory cytokine that has been implicated in the pathogenesis of AD. Recently, we developed a novel DNA vaccine
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::9647a0a1d39058badcfee486ba62b6fa
https://doi.org/10.1016/j.jaci.2009.04.025
https://doi.org/10.1016/j.jaci.2009.04.025
Autor:
Hironori Ando, Yoshifumi Takei, Naohiko Shimada, Atsushi Uno, Kazuo Sakurai, Yoichi Takeda, Susumu Satoh, Yoshikazu Koyama, Shuichiro Uehara
Publikováno v:
Bulletin of the Chemical Society of Japan. 81:1485-1491
Aptamers are an attractive candidate for a molecular-targeted drug since they can show ability to precisely recognize proteins with a large affinity similar to antibodies. A drawback of aptamers is...
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::d069feb589fd013c4ce6670ced384ee8
https://doi.org/10.1246/bcsj.81.1485
https://doi.org/10.1246/bcsj.81.1485
Autor:
Shigeki Ohshima, Akio Minami, Kazunori Yasuda, Shin Onodera, Yoshikazu Koyama, Yoichiro Iwakura, Jun Nishihira, Ikkei Matsuda, Harukazu Tohyama
Publikováno v:
Arthritis & Rheumatism. 56:521-530
Objective Previous studies have demonstrated that neutralization of macrophage migration inhibitory factor (MIF) by anti-MIF antibodies decreases joint inflammation and destruction in a type II collagen–induced arthritis model in mice. The aim of t
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c6b0ba93d843b0682f566885ae78a87d
https://doi.org/10.1002/art.22407
https://doi.org/10.1002/art.22407
Autor:
Harukazu Tohyama, Satoshi Sasaki, Nobuyuki Udagawa, Ayako Shiraishi, Minqi Li, Shin Onodera, Shigeki Ohshima, Norio Amizuka, Kazuharu Irie, Jun Nishihira, Yoshikazu Koyama, Kazunori Yasuda
Publikováno v:
Journal of Bone and Mineral Research. 21:876-885
The bone phenotype of mice overexpressing MIF was studied. These mice showed decreased trabecular bone, increased bone formation rate, and increased MMP-3, −9, and −13 mRNA expression in the femora and tibias. This model provides evidence of the
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1b6f35988e92a10dea06567820a6bd44
https://doi.org/10.1359/jbmr.060310
https://doi.org/10.1359/jbmr.060310
Macrophage migration inhibitory factor-deficient mice are resistant to ovariectomy-induced bone loss
Autor:
Norio Amizuka, Shigeki Oshima, Jun Nishihira, Kazunori Yasuda, Akio Minami, Kazuharu Irie, Yoshikazu Koyama, Satoshi Watanabe, Minqi Li, Shin Onodera
Publikováno v:
FEBS Letters. 580(5):1251-1256
A link between macrophage migration inhibitory factor (MIF) and estrogen has recently emerged. We examined the involvement of MIF in osteoporotic changes in bone after ovariectomy (OVX), and revealed that MIF-deficient mice (MIF-KO) were completely p
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::51db2cda16e8ea8f40e7f1f5f01d5f4a
http://hdl.handle.net/2115/5848
http://hdl.handle.net/2115/5848
The effects of Ginkgo biloba extract on lipopolysaccharide-induced inflammation in vitro and in vivo
Autor:
Iliyana Ilieva, Yuko Takemoto, Kenji Shiratori, Yoshikazu Koyama, Satoru Kase, Hirokuni Kitamei, Kazunaga Yazawa, Shigeaki Ohno, Kazuhiko Yoshida, Kazuhiro Ohgami
Publikováno v:
Experimental Eye Research. 79:181-187
Purpose . Ginkgo biloba extract (GBE) contains many different flavone glycosides and terpenoides. Several previous studies have demonstrated that GBE exhibits a wide variety of biological activities, including an antioxidant action, on which we focus
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e7afe6fcba843cb0a5ca1d71dc68d29d
https://doi.org/10.1016/j.exer.2004.03.009
https://doi.org/10.1016/j.exer.2004.03.009
Autor:
Shin Onodera, Yoshimitsu Aoki, Teruo Ishibashi, Akio Minami, Jun Nishihira, Yoshikazu Koyama, Hiroki Ichiyama, Tokifumi Majima
Publikováno v:
Arthritis & Rheumatism. 50:1437-1447
Objective Interleukin-8 (IL-8) plays an important role in the migration of inflammatory cells into the synovium and joint fluids in rheumatoid arthritis (RA). This study was undertaken to investigate the IL-8 inductive activity of the macrophage migr
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::11185e6e502c57d1154e684ba529d62e
https://doi.org/10.1002/art.20190
https://doi.org/10.1002/art.20190
Autor:
Sakae Tanaka, Shin Onodera, Akio Minami, Kazuhiko Yoshida, Jun Nishihira, Yoshikazu Koyama, Kazuya Iwabuchi
Publikováno v:
Journal of Biological Chemistry. 277:7865-7874
Neutral matrix metalloproteinases (MMPs) play an important role in bone matrix degradation accompanied by bone remodeling. We herein show for the first time that macrophage migration inhibitory factor (MIF) up-regulates MMP-13 (collagenase-3) mRNA of
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::a8f8af8c339f8a4062a15497e32bf9ef
https://doi.org/10.1074/jbc.m106020200
https://doi.org/10.1074/jbc.m106020200