Zobrazeno 1 - 10
of 41
pro vyhledávání: '"Yoshikazu Hirate"'
A possible function of Nik-related kinase in the labyrinth layer of delayed delivery mouse placentas
Autor:
Hiroshi YOMOGITA, Hikaru ITO, Kento HASHIMOTO, Akihiko KUDO, Toshiaki FUKUSHIMA, Tsutomu ENDO, Yoshikazu HIRATE, Yoshihiro AKIMOTO, Masayuki KOMADA, Yoshiakira KANAI, Naoyuki MIYASAKA, Masami KANAI-AZUMA
Publikováno v:
The Journal of Reproduction and Development, Vol 69, Iss 1, Pp 32-40 (2022)
In mice and humans, Nik-related protein kinase (Nrk) is an X-linked gene that encodes a serine/threonine kinase belonging to GCK group 4. Nrk knockout (Nrk KO) mice exhibit delayed delivery, possibly due to defective communication between the Nrk KO
Externí odkaz:
https://doaj.org/article/14275d492c9e423db3f42d0bd1cafa3b
Autor:
Aya Uchida, Kenya Imaimatsu, Honoka Suzuki, Xiao Han, Hiroki Ushioda, Mami Uemura, Kasane Imura-Kishi, Ryuji Hiramatsu, Hinako M. Takase, Yoshikazu Hirate, Atsuo Ogura, Masami Kanai-Azuma, Akihiko Kudo, Yoshiakira Kanai
Publikováno v:
Nature Communications, Vol 13, Iss 1, Pp 1-14 (2022)
A valve-like structure called this Sertoli valve (SV) supports spermatogenesis by modulating the directional fluid flow in mouse testis. The SV formation is supported by its neighboring SOX17 + rete testis (RT). This study highlights the essential ro
Externí odkaz:
https://doaj.org/article/d684a74afeee4977a47f1576a9957d2e
Autor:
Kasane Imura-Kishi, Aya Uchida, Naoki Tsunekawa, Hitomi Suzuki, Hinako M. Takase, Yoshikazu Hirate, Masami Kanai-Azuma, Ryuji Hiramatsu, Masamichi Kurohmaru, Yoshiakira Kanai
Publikováno v:
Scientific Reports, Vol 11, Iss 1, Pp 1-14 (2021)
Abstract In mammalian testes, undifferentiated spermatogonia (Aundiff) undergo differentiation in response to retinoic acid (RA), while their progenitor states are partially maintained by fibroblast growth factors (FGFs). Sertoli valve (SV) is a regi
Externí odkaz:
https://doaj.org/article/8f24b6fde76940158c71023c6e32330f
Autor:
Ryuichi Yamada, Akira Oguri, Katsunori Fujiki, Katsuhiko Shirahige, Yoshikazu Hirate, Masami Kanai-Azuma, Hirotaka Takezoe, Yoshihiro Akimoto, Naoki Takahashi, Yoshiakira Kanai
Publikováno v:
Disease Models & Mechanisms, Vol 14, Iss 12 (2021)
Mutations in human MAB21L1 cause aberrations in lens ectoderm morphogenesis and lead to congenital cerebellar, ocular, craniofacial and genital (COFG) syndrome. Murine Mab21l1-null mutations cause severe cell-autonomous defects in lens formation, lea
Externí odkaz:
https://doaj.org/article/beecd9a2524d4386b477fed048854f1e
Autor:
Kento Miura, Kyoko Harikae, Mayu Nakaguchi, Kenya Imaimatsu, Ryuji Hiramatsu, Ayako Tomita, Yoshikazu Hirate, Masami Kanai-Azuma, Masamichi Kurohmaru, Atsuo Ogura, Yoshiakira Kanai
Publikováno v:
PLoS ONE, Vol 14, Iss 3, p e0212367 (2019)
In most of mammalian embryos, gonadal sex differentiation occurs inside the maternal uterus before birth. In several fetal ovarian grafting experiments using male host mice, an experimental switch from the maternal intrauterine to male-host environme
Externí odkaz:
https://doaj.org/article/006fe5b060b3491292957a1b045cb5da
Autor:
Eryn Wicklow, Stephanie Blij, Tristan Frum, Yoshikazu Hirate, Richard A Lang, Hiroshi Sasaki, Amy Ralston
Publikováno v:
PLoS Genetics, Vol 10, Iss 10, p e1004618 (2014)
Pluripotent epiblast (EPI) cells, present in the inner cell mass (ICM) of the mouse blastocyst, are progenitors of both embryonic stem (ES) cells and the fetus. Discovering how pluripotency genes regulate cell fate decisions in the blastocyst provide
Externí odkaz:
https://doaj.org/article/65e842a109774c90a28b1b9a660b66d8
A possible function of Nik-related kinase in the labyrinth layer of delayed delivery mouse placentas
Autor:
Hiroshi YOMOGITA, Hikaru ITO, Kento HASHIMOTO, Akihiko KUDO, Toshiaki FUKUSHIMA, Tsutomu ENDO, Yoshikazu HIRATE, Yoshihiro AKIMOTO, Masayuki KOMADA, Yoshiakira KANAI, Naoyuki MIYASAKA, Masami KANAI-AZUMA
Publikováno v:
Journal of Reproduction and Development. 69:32-40
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::abad35d6f482f13bdac16a40b17075ec
https://doi.org/10.1262/jrd.2022-120
https://doi.org/10.1262/jrd.2022-120
Autor:
Yoshifumi Fujioka, Hirosuke Shiura, Masayuki Ishii, Ryuichi Ono, Tsutomu Endo, Hiroshi Kiyonari, Yoshikazu Hirate, Hikaru Ito, Masami Kanai-Azuma, Takashi Kohda, Tomoko Kaneko-Ishino, Fumitoshi Ishino
Retrotransposon Gag-like (RTL) 8A, 8B and 8C are triplet genes of uncertain function that form a cluster on the X chromosome. They are eutherian-specific genes presumably derived from a certain retrovirus. Here, we demonstrate thatRtl8aandRtl8bplay a
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::1a2cf69232838374147698cb38e13e6f
https://doi.org/10.1101/2023.05.28.542606
https://doi.org/10.1101/2023.05.28.542606
Autor:
Shiori Kumazawa, Kana Hayakawa, Yoshiakira Kanai, Masami Kanai-Azuma, Kento Miura, Yoshikazu Hirate, Yuki Nakano
Publikováno v:
Sexual Development. 14:40-50
SOX17 activity in the uterine epithelium is essential for the implantation of mouse embryos. Previously, we demonstrated that female Sox17 heterozygous mutant mice are subfertile, and 2 active copies of Sox17 are required for the proper implantation
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::a3db93b4e7bac46f63b6a55f3a4c96bf
https://doi.org/10.1159/000513386
https://doi.org/10.1159/000513386
Autor:
Yoshiakira Kanai, Yoshihiro Akimoto, Masami Kanai-Azuma, Naoki Takahashi, Ryuichi Yamada, Yoshikazu Hirate, Katsuhiko Shirahige, Katsunori Fujiki, Akira Oguri, Hirotaka Takezoe
Publikováno v:
Disease Models & Mechanisms
article-version (VoR) Version of Record
Disease Models & Mechanisms, Vol 14, Iss 12 (2021)
article-version (VoR) Version of Record
Disease Models & Mechanisms, Vol 14, Iss 12 (2021)
Mutations in human MAB21L1 cause aberrations in lens ectoderm morphogenesis and lead to congenital cerebellar, ocular, craniofacial and genital (COFG) syndrome. Murine Mab21l1-null mutations cause severe cell-autonomous defects in lens formation, lea
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::9fb46222d6d8eaaf5fd448c59c83f74a
https://doi.org/10.1242/dmm.049251
https://doi.org/10.1242/dmm.049251