Zobrazeno 1 - 10
of 143
pro vyhledávání: '"Yoshikazu, Yuki"'
Autor:
Yoshikazu Yuki, Shiho Kurokawa, Kotomi Sugiura, Koji Kashima, Shinichi Maruyama, Tomoyuki Yamanoue, Ayaka Honma, Mio Mejima, Natsumi Takeyama, Masaharu Kuroda, Hiroko Kozuka-Hata, Masaaki Oyama, Takehiro Masumura, Rika Nakahashi-Ouchida, Kohtaro Fujihashi, Takashi Hiraizumi, Eiji Goto, Hiroshi Kiyono
Publikováno v:
Frontiers in Plant Science, Vol 15 (2024)
We previously established the selection-marker-free rice-based oral cholera vaccine (MucoRice-CTB) line 51A for human use by Agrobacterium-mediated co-transformation and conducted a double-blind, randomized, placebo-controlled phase I trial in Japan
Externí odkaz:
https://doaj.org/article/7b4a2074dd93404f8d74acfa66ff2b73
Autor:
Shingo Umemoto, Rika Nakahashi-Ouchida, Yoshikazu Yuki, Shiho Kurokawa, Tomonori Machita, Yohei Uchida, Hiromi Mori, Tomoyuki Yamanoue, Takehiko Shibata, Shin-ichi Sawada, Kazuya Ishige, Takashi Hirano, Kohtaro Fujihashi, Kazunari Akiyoshi, Yosuke Kurashima, Daisuke Tokuhara, Peter B Ernst, Masashi Suzuki, Hiroshi Kiyono
Publikováno v:
npj Vaccines, Vol 8, Iss 1, Pp 1-16 (2023)
Abstract Respiratory syncytial virus (RSV) is a leading cause of upper and lower respiratory tract infection, especially in children and the elderly. Various vaccines containing the major transmembrane surface proteins of RSV (proteins F and G) have
Externí odkaz:
https://doaj.org/article/27bafa5bb1384d08a0dc201789536623
Autor:
Naomi Matsumoto, Shiho Kurokawa, Shigeyuki Tamiya, Yutaka Nakamura, Naomi Sakon, Shoko Okitsu, Hiroshi Ushijima, Yoshikazu Yuki, Hiroshi Kiyono, Shintaro Sato
Publikováno v:
Viruses, Vol 15, Iss 9, p 1929 (2023)
Sapoviruses, like noroviruses, are single-stranded positive-sense RNA viruses classified in the family Caliciviridae and are recognized as a causative pathogen of diarrhea in infants and the elderly. Like human norovirus, human sapovirus (HuSaV) has
Externí odkaz:
https://doaj.org/article/2ceea2f522424a2b94665a2dfe4ddce0
Autor:
Rika Nakahashi-Ouchida, Hiromi Mori, Yoshikazu Yuki, Shingo Umemoto, Takashi Hirano, Yohei Uchida, Tomonori Machita, Tomoyuki Yamanoue, Shin-ichi Sawada, Masashi Suzuki, Kohtaro Fujihashi, Kazunari Akiyoshi, Yuichi Kurono, Hiroshi Kiyono
Publikováno v:
Frontiers in Immunology, Vol 13 (2022)
Nontypeable Haemophilus influenzae (NTHi) strains form a major group of pathogenic bacteria that colonizes the nasopharynx and causes otitis media in young children. At present, there is no licensed vaccine for NTHi. Because NTHi colonizes the upper
Externí odkaz:
https://doaj.org/article/a589e942b7ea4e2991656a7fd55bc6f7
Autor:
Yosuke Kurashima, Takaaki Kigoshi, Sayuri Murasaki, Fujimi Arai, Kaoru Shimada, Natsumi Seki, Yun-Gi Kim, Koji Hase, Hiroshi Ohno, Kazuya Kawano, Hiroshi Ashida, Toshihiko Suzuki, Masako Morimoto, Yukari Saito, Ai Sasou, Yuki Goda, Yoshikazu Yuki, Yutaka Inagaki, Hideki Iijima, Wataru Suda, Masahira Hattori, Hiroshi Kiyono
Publikováno v:
Nature Communications, Vol 12, Iss 1, Pp 1-17 (2021)
Glycoprotein-2 (GP-2) can protect the intestinal epithelial barrier from bacteria and is associated with protection against Crohn’s disease. Here, the authors show pancreatic GP-2 is the source of the intestine’s luminal GP-2 that binds bacteria
Externí odkaz:
https://doaj.org/article/f5da787852fa46ccab231d2284892574
Autor:
Ai Sasou, Yoshikazu Yuki, Ayaka Honma, Kotomi Sugiura, Koji Kashima, Hiroko Kozuka-Hata, Masanori Nojima, Masaaki Oyama, Shiho Kurokawa, Shinichi Maruyama, Masaharu Kuroda, Shinjiro Tanoue, Narushi Takamatsu, Kohtaro Fujihashi, Eiji Goto, Hiroshi Kiyono
Publikováno v:
BMC Genomics, Vol 22, Iss 1, Pp 1-12 (2021)
Abstract Background We have previously developed a rice-based oral vaccine against cholera diarrhea, MucoRice-CTB. Using Agrobacterium-mediated co-transformation, we produced the selection marker–free MucoRice-CTB line 51A, which has three copies o
Externí odkaz:
https://doaj.org/article/7aaaddf9d20e428fb3829ef245994d4d
Autor:
Yoshikazu Yuki, Fanglei Zuo, Shiho Kurokawa, Yohei Uchida, Shintaro Sato, Naomi Sakon, Lennart Hammarström, Hiroshi Kiyono, Harold Marcotte
Publikováno v:
Pharmaceutics, Vol 15, Iss 1, p 63 (2022)
Passive administration of neutralizing antibodies (Abs) is an attractive strategy for the control of gastrointestinal infections. However, an unanswered practical concern is the need to assure the stability of sufficient amounts of orally administere
Externí odkaz:
https://doaj.org/article/3e7bc6b28103461aa7fce4ed3453fa91
Autor:
Yoshikazu Yuki, PhD, Masanori Nojima, MD, Osamu Hosono, MD, Hirotoshi Tanaka, ProfMD, Yasumasa Kimura, PhD, Takeshi Satoh, PhD, Seiya Imoto, ProfPhD, Satoshi Uematsu, ProfMD, Shiho Kurokawa, PhD, Koji Kashima, PhD, Mio Mejima, PhD, Rika Nakahashi-Ouchida, PhD, Yohei Uchida, MS, Takanori Marui, MS, Noritada Yoshikawa, MD, Fumitaka Nagamura, ProfMD, Kohtaro Fujihashi, ProfDDS, Hiroshi Kiyono, ProfDDS
Publikováno v:
The Lancet Microbe, Vol 2, Iss 9, Pp e429-e440 (2021)
Summary: Background: There are an estimated 1·3–4·0 million cases of cholera and 20 000–140 000 cholera-related deaths worldwide each year. The rice-based cholera toxin B subunit (CTB) vaccine, MucoRice-CTB, is an oral candidate vaccine that do
Externí odkaz:
https://doaj.org/article/b7638b4df71d421f8e095b3d4a553c5c
Autor:
Ai Sasou, Yoshikazu Yuki, Shiho Kurokawa, Shintaro Sato, Yuki Goda, Masao Uchida, Naomi Matsumoto, Hiroshi Sagara, Yuji Watanabe, Masaharu Kuroda, Naomi Sakon, Kotomi Sugiura, Rika Nakahashi-Ouchida, Hiroshi Ushijima, Kohtaro Fujihashi, Hiroshi Kiyono
Publikováno v:
Frontiers in Plant Science, Vol 12 (2021)
Human norovirus is the leading cause of acute nonbacterial gastroenteritis in people of all ages worldwide. Currently, no licensed norovirus vaccine, pharmaceutical drug, or therapy is available for the control of norovirus infection. Here, we used a
Externí odkaz:
https://doaj.org/article/9937d09c43254d55a487153881383382
Autor:
Sheikh Ariful Hoque, Tomohiro Kotaki, Ngan Thi Kim Pham, Yuko Onda, Shoko Okitsu, Shintaro Sato, Yoshikazu Yuki, Takeshi Kobayashi, Niwat Maneekarn, Hiroshi Kiyono, Satoshi Hayakawa, Hiroshi Ushijima
Publikováno v:
Journal of Infection. 86:154-225
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::88765c4b517273de94196a42e4cf00c4
https://doi.org/10.1016/j.jinf.2022.11.007
https://doi.org/10.1016/j.jinf.2022.11.007