Zobrazeno 1 - 10
of 558
pro vyhledávání: '"Yoshikazu, Nakamura"'
Autor:
Toshiaki Nonaka, Ryusuke Ae, Koki Kosami, Hiroya Tange, Miho Kaneko, Takehiro Nakagaki, Tsuyoshi Hamaguchi, Nobuo Sanjo, Yoshikazu Nakamura, Tetsuyuki Kitamoto, Yoshiyuki Kuroiwa, Kensaku Kasuga, Manabu Doyu, Fumiaki Tanaka, Koji Abe, Shigeo Murayama, Ichiro Yabe, Hideki Mochizuki, Takuya Matsushita, Hiroyuki Murai, Masashi Aoki, Koji Fujita, Masafumi Harada, Masaki Takao, Tadashi Tsukamoto, Yasushi Iwasaki, Masahito Yamada, Hidehiro Mizusawa, Katsuya Satoh, Noriyuki Nishida
Publikováno v:
Diagnostics, Vol 14, Iss 21, p 2424 (2024)
Background/Objectives: Sporadic Creutzfeldt–Jakob disease (sCJD) is a fatal neurodegenerative disorder traditionally diagnosed based on the World Health Organization (WHO) criteria in 1998. Recently, Hermann et al. proposed updated diagnostic crite
Externí odkaz:
https://doaj.org/article/1d7e4d35198745628c5f312cf6064510
Publikováno v:
iScience, Vol 26, Iss 3, Pp 106258- (2023)
Summary: Osmoregulation is an essential homeostatic process that requires constant release of vasopressin during sustained increases in plasma osmolality. The magnocellular neurosecretory cells (MNCs) respond to increases in external osmolality throu
Externí odkaz:
https://doaj.org/article/cd70fce54cd944daa951135da7ca96cc
Autor:
Hideaki Kai, Kenta Teruya, Atsuko Takeuchi, Yoshikazu Nakamura, Hidehiro Mizusawa, Masahito Yamada, Tetsuyuki Kitamoto
Publikováno v:
Heliyon, Vol 9, Iss 3, Pp e13974- (2023)
The polymorphic heterozygosity of PRNP at codon 129 or 219 prevents the onset of sporadic Creutzfeldt-Jakob disease (sCJD). We investigated the association between polymorphic genotypes at codon 129 or 219 and comprehensive prion disease onset using
Externí odkaz:
https://doaj.org/article/cfe210c0f1af49a286d17a58750424fe
Autor:
Kaori Kanemaru, Makoto Shimozawa, Manabu Kitamata, Rikuto Furuishi, Hinako Kayano, Yui Sukawa, Yuuki Chiba, Takatsugu Fukuyama, Junya Hasegawa, Hiroki Nakanishi, Takuma Kishimoto, Kazuya Tsujita, Kazuma Tanaka, Toshiki Itoh, Junko Sasaki, Takehiko Sasaki, Kiyoko Fukami, Yoshikazu Nakamura
Publikováno v:
Nature Communications, Vol 13, Iss 1, Pp 1-15 (2022)
Epithelial cells provide cell-cell adhesion to maintain the integrity of multicellular organisms. Here the authors show that phospholipid phosphatidylinositol (4,5)-bisphosphate is critical for the maintenance of epithelial characteristics.
Externí odkaz:
https://doaj.org/article/7823ce0d20e645f189c00d1084489ae8
Autor:
Kazuya Tsujita, Reiko Satow, Shinobu Asada, Yoshikazu Nakamura, Luis Arnes, Keisuke Sako, Yasuyuki Fujita, Kiyoko Fukami, Toshiki Itoh
Publikováno v:
Nature Communications, Vol 12, Iss 1, Pp 1-14 (2021)
Changes in cell mechanics contribute to cancer cell dissemination. Here the authors show that high plasma membrane (PM) tension inhibits cancer dissemination by counteracting mechanosensitive BAR family protein assembly, while restoration of PM tensi
Externí odkaz:
https://doaj.org/article/cbe9da96697e4617972f9c2d3614eb29
Autor:
Kaori Kanemaru, Yoshikazu Nakamura
Publikováno v:
Biomolecules, Vol 13, Iss 6, p 915 (2023)
Phospholipase C (PLC) plays pivotal roles in regulating various cellular functions by metabolizing phosphatidylinositol 4,5-bisphosphate in the plasma membrane. This process generates two second messengers, inositol 1,4,5-trisphosphate and diacylglyc
Externí odkaz:
https://doaj.org/article/fae8157a06914504b0517f66f8a9f9ab
Autor:
Yusaku Matsuda, Yosuke Nonaka, Satoshi Futakawa, Hirotaka Imai, Kazumasa Akita, Toshiaki Nishihata, Masatoshi Fujiwara, Yusuf Ali, Robert B. Bhisitkul, Yoshikazu Nakamura
Publikováno v:
Molecular Therapy: Nucleic Acids, Vol 17, Iss , Pp 819-828 (2019)
Currently approved therapies for age-related macular degeneration (AMD) are inhibitors against vascular endothelial growth factor (VEGF), which is a major contributor to the pathogenesis of neovascular AMD (nAMD). Intravitreal injections of anti-VEGF
Externí odkaz:
https://doaj.org/article/80978e83ce7e4da59a94b6e8f58f10e5
Autor:
Nozomi Yokota, Ryusuke Ae, Masaki Amenomori, Koji Kitagawa, Takuya Nakamura, Tetsuro Yokota, Kato Masato, Teppei Sasahara, Yuri Matsubara, Koki Kosami, Yoshikazu Nakamura
Publikováno v:
Journal of General and Family Medicine, Vol 20, Iss 4, Pp 139-145 (2019)
Abstract Objective Few studies have reported the influence of clinical background factors on the outcome of Helicobacter pylori eradication therapy in primary care practice. We aimed to determine which clinical background factors influence the outcom
Externí odkaz:
https://doaj.org/article/4fa1cd1f5d334a1cbdd3a168070c5b3b
Autor:
Denan Jin, Shinji Takai, Yosuke Nonaka, Satoko Yamazaki, Masatoshi Fujiwara, Yoshikazu Nakamura
Publikováno v:
Molecular Therapy: Nucleic Acids, Vol 14, Iss , Pp 41-51 (2019)
We have reported that mast cell chymase, an angiotensin II-generating enzyme, is important in cardiovascular tissues. Recently, we developed a new chymase-specific inhibitory RNA aptamer, HA28, and we evaluated the effects of HA28 on cardiac function
Externí odkaz:
https://doaj.org/article/df37865be8184ae1bbf629995fa6b705
Autor:
Yoshikazu Nakamura
Publikováno v:
Cells, Vol 10, Iss 7, p 1617 (2021)
Vascular endothelial growth factor (VEGF) plays a pivotal role in angiogenesis, but is not the only player with an angiogenic function. Fibroblast growth factor-2 (FGF2), which was discovered before VEGF, is also an angiogenic growth factor. It has b
Externí odkaz:
https://doaj.org/article/abc5f068246b40cab9ecd24691e00f65