Zobrazeno 1 - 10
of 127
pro vyhledávání: '"Yoshikazu, Kuwahara"'
Autor:
Kazuo Tomita, Yoshikazu Kuwahara, Kento Igarashi, Junichi Kitanaka, Nobue Kitanaka, Yuko Takashi, Koh-ichi Tanaka, Mehryar Habibi Roudkenar, Amaneh Mohammadi Roushandeh, Akihiro Kurimasa, Yoshihiro Nishitani, Tomoaki Sato
Publikováno v:
Japanese Dental Science Review, Vol 59, Iss , Pp 431-438 (2023)
Patients with neurological diseases, such as schizophrenia, tend to show low K+-Cl- co-transporter 2 (KCC2) levels in the brain. The cause of these diseases has been associated with stress and neuroinflammation. However, since the pathogenesis of the
Externí odkaz:
https://doaj.org/article/e727f14819824679bcf66fd6b2e36fd6
Autor:
Shunsuke Gohara, Kosuke Shinohara, Ryoji Yoshida, Ryusho Kariya, Hiroshi Tazawa, Masashi Hashimoto, Junki Inoue, Ryuta Kubo, Hikaru Nakashima, Hidetaka Arita, Sho Kawaguchi, Keisuke Yamana, Yuka Nagao, Asuka Iwamoto, Junki Sakata, Yuichiro Matsuoka, Hisashi Takeshita, Masatoshi Hirayama, Kenta Kawahara, Masashi Nagata, Akiyuki Hirosue, Yoshikazu Kuwahara, Manabu Fukumoto, Seiji Okada, Yasuo Urata, Toshiyoshi Fujiwara, Hideki Nakayama
Publikováno v:
Molecular Therapy: Oncolytics, Vol 27, Iss , Pp 141-156 (2022)
We evaluated the usefulness of an oncolytic virus (Suratadenoturev; OBP-301) against radioresistant oral squamous cell carcinoma. We confirmed the expression of human telomerase reverse transcriptase and the coxsackievirus and adenovirus receptor in
Externí odkaz:
https://doaj.org/article/d144859a11544e3599362d9d41188672
Autor:
Hamed Hosseinalizadeh, Mehryar Habibi Roudkenar, Amaneh Mohammadi Roushandeh, Yoshikazu Kuwahara, Kazuo Tomita, Tomoaki Sato
Publikováno v:
Discover Oncology, Vol 13, Iss 1, Pp 1-19 (2022)
Abstract Glioblastoma (GBM) is one of the most difficult cancers to treat because GBM has the high therapeutic resistance. Recently, immunotherapies for GBM have been used instead of conventional treatments. Among them, Natural killer (NK) cell-based
Externí odkaz:
https://doaj.org/article/3618d8d576554817893157a27b68a611
Autor:
Roman Fukui, Ryo Saga, Yusuke Matsuya, Kazuo Tomita, Yoshikazu Kuwahara, Kentaro Ohuchi, Tomoaki Sato, Kazuhiko Okumura, Hiroyuki Date, Manabu Fukumoto, Yoichiro Hosokawa
Publikováno v:
Scientific Reports, Vol 12, Iss 1, Pp 1-12 (2022)
Abstract Cancer stem-like cells (CSCs) within solid tumors exhibit radioresistance, leading to recurrence and distant metastasis after radiotherapy. To experimentally study the characteristics of CSCs, radioresistant cell lines were successfully esta
Externí odkaz:
https://doaj.org/article/b9f986bf3be149b6982973fd1e3addd7
Autor:
Keisuke Yamana, Junki Inoue, Ryoji Yoshida, Junki Sakata, Hikaru Nakashima, Hidetaka Arita, Sho Kawaguchi, Shunsuke Gohara, Yuka Nagao, Hisashi Takeshita, Manabu Maeshiro, Rin Liu, Yuichiro Matsuoka, Masatoshi Hirayama, Kenta Kawahara, Masashi Nagata, Akiyuki Hirosue, Ryo Toya, Ryuji Murakami, Yoshikazu Kuwahara, Manabu Fukumoto, Hideki Nakayama
Publikováno v:
Journal of Extracellular Vesicles, Vol 10, Iss 14, Pp n/a-n/a (2021)
Abstract Despite advancements in treatments, oral squamous cell carcinoma (OSCC) has not significantly improved in prognosis or survival rate primarily due to the presence of treatment‐resistant OSCC. The intercellular communication between tumour
Externí odkaz:
https://doaj.org/article/8eaae5927b594480ad24b281659d792d
Autor:
Kazuki Hasegawa, Ryo Saga, Kentaro Ohuchi, Yoshikazu Kuwahara, Kazuo Tomita, Kazuhiko Okumura, Tomoaki Sato, Manabu Fukumoto, Eichi Tsuruga, Yoichiro Hosokawa
Publikováno v:
Cells, Vol 11, Iss 23, p 3780 (2022)
Radioresistant (RR) cells are poor prognostic factors for tumor recurrence and metastasis after radiotherapy. The hyaluronan (HA) synthesis inhibitor, 4-methylumbelliferone (4-MU), shows anti-tumor and anti-metastatic effects through suppressing HA s
Externí odkaz:
https://doaj.org/article/e8f4a19d15614a2992999b86da318b05
Autor:
Ali Hosseini, Fatemeh Amiri, Fereshteh Khalighi, Amaneh Mohammadi Roushandeh, Yoshikazu Kuwahara, Hamed Bashiri, Mehryar Habibi Roudkenar
Publikováno v:
Iranian Journal of Medical Sciences, Vol 44, Iss 6, Pp 493-500 (2019)
Background: Due to oxidative stress, hypoxia, and serum deprivation, a large percentage of mesenchymal stem cells (MSCs) die in the early stages of transplantation. The present study aimed to address whether induction or inhibition of autophagy would
Externí odkaz:
https://doaj.org/article/33fd9b8ad75b4aa5963950f80b71f46d
Autor:
Yoshikazu Kuwahara, Kazuo Tomita, Mehryar Habibi Roudkenar, Amaneh Mohammadi Roushandeh, Tomoaki Sato, Akihiro Kurimasa
Publikováno v:
Human Cell. 36:963-971
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::d1ae70e0365aaf3ddbff930a593a3ba4
https://doi.org/10.1007/s13577-023-00871-0
https://doi.org/10.1007/s13577-023-00871-0
Autor:
Yoshikazu Kuwahara PhD, Kazuo Tomita PhD, Mehryar Habibi Roudkenar PhD, Amaneh Mohammadi Roushandeh PhD, Yusuke Urushihara PhD, Kento Igarashi PhD, Taisuke Nagasawa DDS, Akihiro Kurimasa MD, PhD, Manabu Fukumoto MD, PhD, Tomoaki Sato DDS, PhD
Publikováno v:
Technology in Cancer Research & Treatment, Vol 19 (2020)
Background: Radiation therapy is a highly cost-effective treatment for cancer, but the existence of radio-resistant cells remains the most critical obstacle in radiotherapy. We have been established clinically relevant radioresistant (CRR) cell lines
Externí odkaz:
https://doaj.org/article/43a424dceef7490d9ef73917c96bfa07
Autor:
Yuko Takashi, Kazuo Tomita, Yoshikazu Kuwahara, Hideki Nabika, Kento Igarashi, Taisuke Nagasawa, Akihiro Kurimasa, Manabu Fukumoto, Yoshihiro Nishitani, Tomoaki Sato
Publikováno v:
Data in Brief, Vol 20, Iss , Pp 402-410 (2018)
We present data about mitochondrial DNA (mtDNA) copy number and aquaporin (AQP) gene expression in clinically radioresistant (CRR), ρ0, and their parental cells from human cervical cancer and human tongue squamous cell carcinoma. In both ρ0 and CRR
Externí odkaz:
https://doaj.org/article/e9727d12b96d4928b51bc00a61d2ac2d