Zobrazeno 1 - 10
of 80
pro vyhledávání: '"Yoshikazu, Hattori"'
Autor:
Yoshiyuki Tanaka, Daichi Yamanaka, Saori Morioka, Taishi Yamaguchi, Masayuki Morikawa, Takashi S. Kodama, Vladimír Sychrovský, Chojiro Kojima, Yoshikazu Hattori
Publikováno v:
Biophysica, Vol 2, Iss 3, Pp 221-239 (2022)
The catalytic mechanism of hammerhead ribozymes (HHRzs) attracted great attention in relation to the chemical origin of life. However, the basicity (pKa) of the catalytic sites of HHRzs has not been studied so far. As a result, the investigation of t
Externí odkaz:
https://doaj.org/article/4c134b0657e842748d786bc8aeb18731
Autor:
Shoko Shinya, Ritsuko Katahira, Kyoko Furuita, Toshihiko Sugiki, Young-Ho Lee, Yoshikazu Hattori, Kohei Takeshita, Atsushi Nakagawa, Aoi Kokago, Ken-ichi Akagi, Muneki Oouchi, Fumiaki Hayashi, Takanori Kigawa, Midori Takimoto-Kamimura, Toshimichi Fujiwara, Chojiro Kojima
Publikováno v:
RSC Medicinal Chemistry. 13:1100-1111
19F-NMR analysis using the optimized 19F chemical library enables the modeling of the structure of the weakly bound protein–compound complex, overcoming the difficulty in fragment-based drug discovery.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::8a4bd97cf852c69003c817b3f14ba2ec
https://doi.org/10.1039/d2md00170e
https://doi.org/10.1039/d2md00170e
Autor:
Takashi S. Kodama, Kyoko Furuita, Toshihiko Sugiki, Ken-ichi Akagi, Yoko Monobe, Yoshiaki Enokizono, Noriko Monden, Misaki Nakamura, Yoshikazu Hattori, Kohsuke Inomata, Masahiro Shirakawa, Hidehito Tochio, Toshimichi Fujiwara, Chojiro Kojima
With in-cell NMR, the structural and dynamic features of proteins can be analyzed directly in living cells at atomic resolution. However, in mammalian cells, such as human cells, the structural/dynamic features and physiological functions are not ful
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::a836f1d42940e52bfadc4d47e3a9005e
https://doi.org/10.21203/rs.3.rs-2095218/v1
https://doi.org/10.21203/rs.3.rs-2095218/v1
Autor:
Shoko, Shinya, Ritsuko, Katahira, Kyoko, Furuita, Toshihiko, Sugiki, Young-Ho, Lee, Yoshikazu, Hattori, Kohei, Takeshita, Atsushi, Nakagawa, Aoi, Kokago, Ken-ichi, Akagi, Muneki, Oouchi, Fumiaki, Hayashi, Takanori, Kigawa, Midori, Takimoto-Kamimura, Toshimichi, Fujiwara, Chojiro, Kojima
Publikováno v:
RSC Medicinal Chemistry.
Fragment-based drug discovery (FBDD), which involves small compounds
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=jairo_______::c3830ebf3051385a4b8f25201d1760e7
http://hdl.handle.net/10131/00014763
http://hdl.handle.net/10131/00014763
Autor:
Issei Nomura, Akira Ono, Yoshikazu Hattori, Ryo Yamada, Yosuke Matsuda, Hirokazu Tada, Yoshiyuki Tanaka, Yuki Yamaguchi
Publikováno v:
Nucleosides, Nucleotides & Nucleic Acids. 39:1083-1087
Electrical properties of metal-mediated DNA duplexes (metallo-DNA) have been of particular interest because of their potential applications in DNA-based nanoelectronics. We prepared HgII-mediated D...
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::2007a87f39bb573381f54f308763f389
https://doi.org/10.1080/15257770.2020.1755044
https://doi.org/10.1080/15257770.2020.1755044
Autor:
Yoshikazu Hattori1, Daichi Yamanaka2, Saori Morioka1, Taishi Yamaguchi1, Honoka Tomonari1, Chojiro Kojima3,4, Yoshiyuki Tanaka1,2 tanakay@ph.bunri-ac.jp
Publikováno v:
Nucleosides, Nucleotides & Nucleic Acids. 2018, Vol. 37 Issue 7, p383-396. 14p.
Autor:
Daiki Mori, Yoshikazu Hattori
Publikováno v:
IROS
Automobiles or robots with advanced autonomous systems are equipped with multiple types of sensors to overcome different weather and geographical conditions. These sensors generally have various data delays and sampling rates. Additionally, the commu
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::b11ca00f6abcd05345779776f4a7ee4f
https://doi.org/10.1109/iros45743.2020.9341184
https://doi.org/10.1109/iros45743.2020.9341184
Autor:
Kyoko, Furuita, Toshihiko, Sugiki, Mika, Takamuku, Yoshikazu, Hattori, Masatomo, So, Yasushi, Kawata, Takahisa, Ikegami, Toshimichi, Fujiwara, Chojiro, Kojima
Publikováno v:
Journal of magnetic resonance (San Diego, Calif. : 1997). 322
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::4d3c33709ad2885e011d0d022f49096f
https://pubmed.ncbi.nlm.nih.gov/33285399
https://pubmed.ncbi.nlm.nih.gov/33285399
Autor:
Ryo, Yamada, Issei, Nomura, Yuki, Yamaguchi, Yosuke, Matsuda, Yoshikazu, Hattori, Hirokazu, Tada, Akira, Ono, Yoshiyuki, Tanaka
Publikováno v:
Nucleosides, nucleotidesnucleic acids. 39(8)
Electrical properties of metal-mediated DNA duplexes (metallo-DNA) have been of particular interest because of their potential applications in DNA-based nanoelectronics. We prepared Hg
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::7f423771ebf838f545279b0960afff49
https://pubmed.ncbi.nlm.nih.gov/32345125
https://pubmed.ncbi.nlm.nih.gov/32345125
Autor:
Daichi Yamanaka, Chojiro Kojima, Taishi Yamaguchi, Saori Morioka, Yoshikazu Hattori, Yoshiyuki Tanaka, Honoka Tomonari
Publikováno v:
Nucleosides, Nucleotides & Nucleic Acids. 37:383-396
Hammerhead ribozymes are a model system for studying molecular mechanism of RNA catalysis. Physicochemical data-driven mechanistic studies are an indispensable step towards understanding the catalysis of hammerhead ribozymes. Here we characterized a
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::292e83dd02ba834d2bd4be3725114e78
https://doi.org/10.1080/15257770.2018.1473877
https://doi.org/10.1080/15257770.2018.1473877