Zobrazeno 1 - 10
of 26
pro vyhledávání: '"Yoshihito Yamakoshi"'
Autor:
Takuya Mori, Hiroaki Tanaka, Sota Deguchi, Yoshihito Yamakoshi, Yuichiro Miki, Mami Yoshii, Tatsuro Tamura, Takahiro Toyokawa, Shigeru Lee, Kazuya Muguruma, Masaichi Ohira
Publikováno v:
PLoS ONE, Vol 17, Iss 1, p e0262455 (2022)
Nivolumab, an immune checkpoint blocker, has been approved for advanced gastric cancer (GC), but predictive factors of nivolumab's efficacy in patients with GC, especially immune cells such as tissue-resident memory T cells or those forming tertiary
Externí odkaz:
https://doaj.org/article/351ffe9fd8b34d2b9a763be8ee84c192
Tertiary lymphoid structures show infiltration of effective tumor‐resident T cells in gastric cancer
Autor:
Yoshihito Yamakoshi, Yuichiro Miki, Mami Yoshii, Sota Deguchi, Shugo Suzuki, Takuya Mori, Tatsuro Tamura, Kazuya Muguruma, Takahiro Toyokawa, Shigeru Lee, Masaichi Ohira, Hideki Wanibuchi, Hiroaki Tanaka
Publikováno v:
Cancer Science
Several studies have reported that tissue‐resident memory T cells (TRM cells) or tertiary lymphoid structures (TLSs) are associated with a good prognosis. The aim of this study was to clarify the association of TRM cells and TLSs in the tumor immun
Autor:
Wataru, Goto, Mizuki, Nagamori, Yoshihito, Yamakoshi, Shinya, Nomura, Tsutomu, Takashima, Hiroshi, Otani, Masaichi, Ohira
Publikováno v:
Gan to kagaku ryoho. Cancerchemotherapy. 48(13)
Primary adenoid cystic carcinoma(ACC)of the breast is a rare type of breast cancer. A 53-year-old woman with a right breast mass was examined at our institute. Ultrasonography showed 12.5×10.3×8.4 mm sized an ill-defined hypoechoic mass at zone C o
Autor:
Yoshihito, Yamakoshi, Hiroshi, Ohtani, Mizuki, Nagamori, Shinya, Nomura, Hiroji, Nakagawa, Mami, Yoshii, Tatsuro, Tamura, Takahiro, Toyokawa, Hiroaki, Tanaka, Kazuya, Muguruma, Masaichi, Ohira
Publikováno v:
Gan to kagaku ryoho. Cancerchemotherapy. 47(13)
A 69-year-old woman, who complained of appetite loss, was diagnosed with Type 3 gastric cancer, and a biopsy resulted in the diagnosis of adenocarcinoma(tub2-por), Group 5. Abdominal computed tomography (CT) revealed bulky metastatic lymph nodes arou
Autor:
Sota Deguchi, Yoshihito Yamakoshi, Masaichi Ohira, Mami Yoshii, Takahiro Toyokawa, Tatsuro Tamura, Kazuya Muguruma, Shigeru Lee, Junya Nishimura, Hiroaki Tanaka
Publikováno v:
In Vivo
Background/aim Neoadjuvant chemotherapy (NAC) using 5-FU (5-fluorouracil)/CDDP (cisplatin) is a standard therapy for stage II/III thoracic esophageal squamous cell carcinoma (ESCC) in Japan. The aim of this study was to investigate whether 5-FU/CDDP
Autor:
Hiroaki, Tanaka, Yoshihito, Yamakoshi, Chie, Sakimura, Takuya, Mori, Sota, Deguchi, Yuichiro, Miki, Mami, Yoshii, Tatsuro, Tamura, Takahiro, Toyokawa, Kazuya, Muguruma, Masaichi, Ohira
Publikováno v:
Gan to kagaku ryoho. Cancerchemotherapy. 47(9)
Currently, the immunotherapy approved for gastric cancer is immune checkpoint blockade( ICB) therapy. The effects of ICB depend on the T cell-mediated immune response elicited at the cancer site. Based on the results of previous clinical trials, it i
Autor:
Soichiro Hiramatsu, Tatsuro Tamura, Kosei Hirakawa, Masaichi Ohira, Junya Nishimura, Takahiro Toyokawa, Chie Sakimura, Kazuya Muguruma, Masakazu Yashiro, Yoshihito Yamakoshi, Hiroaki Tanaka
Publikováno v:
Oncology Reports.
Tumor‑associated neutrophils (TANs) have an immunosuppressive function and play an important role in tumor progression. However, the detailed mechanism is largely unknown. The present study investigated the immunosuppressive ability of TANs in gast
Autor:
Kosei Hirakawa, Masaichi Ohira, Takuya Mori, Yoshihito Yamakoshi, Chie Sakimura, Hiroaki Tanaka, Tatsuro Tamura, Sota Deguchi, Takahiro Toyokawa, Kazuya Muguruma
Publikováno v:
International Journal of Oncology
Tertiary lymphoid structures (TLSs), which consist of B cells, T cells, follicular dendritic cells and high endothelial venules, have recently been found to be associated with effective antitumor immune responses in patients with cancer. Tumor-infilt
Autor:
JUNYA NISHIMURA, SOTA DEGUCHI, HIROAKI TANAKA, YOSHIHITO YAMAKOSHI, MAMI YOSHII, TATSURO TAMURA, TAKAHIRO TOYOKAWA, SHIGERU LEE, KAZUYA MUGURUMA, MASAICHI OHIRA
Publikováno v:
In Vivo; Mar/Apr2021, Vol. 35 Issue 2, p743-752, 10p
Autor:
Masaichi Ohira, Junya Nishimura, Yoshihito Yamakoshi, Kiyoshi Maeda, Kosei Hirakawa, Kazuya Muguruma, Hiroaki Tanaka, Soichiro Hiramatsu, Tatsuro Tamura, Takahiro Toyokawa
Publikováno v:
Esophagus : official journal of the Japan Esophageal Society. 16(4)
Dendritic cells (DCs) are the most potent antigen-presenting cells to induce cytotoxic T lymphocytes in the tumor environment. After acquiring antigens, DCs undergo maturation and their expression of MHC and co-stimulation molecules are enhanced, alo