Zobrazeno 1 - 10
of 64
pro vyhledávání: '"Yoshihisa Nagatoshi"'
Autor:
Michio Kaneko, Yuji Ishida, Yoshihisa Nagatoshi, Toshimi Kimura, Kohmei Ida, Atsushi Makimoto, Yasuo Ohashi, Masaaki Kumagai, Hideo Mugishima, Takashi Taga
Publikováno v:
Pediatrics International. 61:453-458
Background Although irinotecan hydrochloride (IRI) is a promising chemotherapeutic agent for pediatric solid tumors, its indications had been off-label in the USA, EU and Japan. Therefore, we conducted a phase 1/2 trial of IRI monotherapy in a regist
Autor:
Megumi Oda, Hideo Mugishima, Tetsuya Mori, Yasuo Horikoshi, Yoshifumi Kawano, Yasuhiro Okamoto, Shunichi Kato, Akira Kikuchi, Makoto Kaneda, Masahiro Tsuchida, Yoshihisa Nagatoshi, Shuichi Taniguchi, Yoshiyuki Kosaka, Hisato Kigasawa
Publikováno v:
Pediatric Transplantation. 18:294-301
The aim of this study was to prospectively evaluate the PK and safety of ivBU in 25 Japanese children (median age six yr; range, five months-17 yr) as one of a combination of drugs in a pretransplant regimen. The patients had acute leukemia (n = 14),
Autor:
Nobuhiro Ito, Reiji Fukano, Yoshifumi Kawano, Takuro Nishikawa, Kentaro Nakashima, Daisuke Sawa, Yoshihisa Nagatoshi, Jiro Inagaki, Jun Okamura
Publikováno v:
Pediatric Transplantation. 16:722-728
The impact of a second all-SCT on the long-term outcomes of children who relapse after allo-SCT has been unclear. We retrospectively analyzed the long-term outcomes of different salvage treatments for such children. Sixty-six children with hematologi
Autor:
Tadashi Anan, Ryosuke Miyaji, Shinichiro Nakagawa, Hirokazu Kanegane, Yoko Shioda, Masahiro Yasui, Yoshihisa Nagatoshi, Miharu Yabe, Toshihiko Imamura, Akitoshi Kinoshita, Akira Morimoto, Junji Kamizono, Hisaya Nakadate, Hisamichi Tauchi, Kazuko Kudo, Asahito Hama, Takashi Sato
Publikováno v:
Pediatric Blood & Cancer. 56:110-115
Background Several studies have suggested that Langerhans cell histiocytosis (LCH) is responsive to treatment with bisphosphonates (BPs). However the efficacy and safety of BPs therapy for childhood LCH is unknown. Procedure Data on children with LCH
Autor:
Junji Tanaka, H Akiyama, Keisei Kawa, Makoto Hirokawa, Hiroatsu Iida, Shinichiro Okamoto, Takashi Ashida, Tetsuya Eto, Akira Kikuchi, K Miyamura, Yoshihiro Inamoto, Yasuo Morishima, S Mori, Yoshihisa Nagatoshi, Masahiro Tsuchida
Publikováno v:
Bone Marrow Transplantation. 46:1192-1202
Cell dose is one of the major factors that can be manipulated in unrelated BMT. However, regarding disease-stage-stratified effects of cell dose, data are limited. We analyzed the registry data from 3559 patients with acute leukemia, CML and myelodys
Autor:
Ken Tabuchi, Koji Kato, Koichi Oshima, Ryoji Kobayashi, Ryoji Hanada, Shunichi Kato, Yoshihisa Nagatoshi
Publikováno v:
Pediatric Transplantation. 14:657-663
We studied the outcome of allogeneic HSCT in patients with SCN. Between 1989 and 2005, 18 patients with SCN in Japan received HSCT for reasons other than malignant transformation, i.e., because of the lack of or a partial response to treatment with r
Autor:
Y Ishida, Shingo Kato, Akira Morimoto, Yoshihisa Nagatoshi, Daiichiro Hasegawa, Eiichi Ishii, Shouichi Ohga, Kazuko Kudo, Nobuhiro Suzuki
Publikováno v:
Bone Marrow Transplantation. 45:901-906
Langerhans cell histiocytosis (LCH) that is refractory to conventional chemotherapy has a poor outcome. Hematopoietic stem cell transplantation (SCT) is a promising approach for refractory LCH because of its immunomodulatory effect. In this study, th
Autor:
Jun Okamura, Daijiro Takahashi, Morisige Takeshita, Jun Nagayama, Jiro Inagaki, Nobuyoshi Itonoaga, Yoshihisa Nagatoshi
Publikováno v:
Journal of Pediatric Hematology/Oncology. 30:696-700
It is extremely rare that a patient with anaplastic large cell lymphoma (ALCL) demonstrates circulating lymphoma cells. A 10-year-old Japanese boy was presented with high-grade fever and cough. The physical examination revealed marked hepatosplenomeg
Autor:
Yoshinao Oda, Kenichi Kohashi, Shouichi Ohga, Masataka Ishimura, Hidetoshi Takada, Jun Okamura, Tatsuro Tajiri, Yoshihisa Nagatoshi, Toshiro Hara
Publikováno v:
Pediatric Transplantation. 11:945-949
A 13-yr-old boy developed post-transplant liver tumor. At three yrs of age, this patient underwent a histocompatible sibling donor BMT for severe aplastic anemia, after a conditioning with antithymocyte globulin and cyclophosphamide. He became a HBV
Publikováno v:
Bone Marrow Transplantation. 41:571-577
We report the results of a retrospective analysis in 27 pediatric patients who received low-dose MTX as the second-line treatment for steroid-refractory or -dependent acute and chronic GVHD. Between July 2000 and May 2006, 10 patients with aGVHD and