Zobrazeno 1 - 10
of 87
pro vyhledávání: '"Yoshihisa Koga"'
Autor:
Yuto Matsuura, Yoshinori Watanabe, Hiroshi Taniguchi, Yoshihisa Koga, Fumiko Yasuno, Tomomi Sakai
Publikováno v:
Clinical Medicine Insights: Case Reports, Vol 13 (2020)
Introduction: Bipolar disorder (BD) is typically treated by pharmacotherapy. However, pharmacotherapy alone is often not adequate to cope with the variety of symptoms associated with BD. The present case report describes the therapeutic effects of ma
Externí odkaz:
https://doaj.org/article/0576cfecca614ce69aee2494e531ca55
Autor:
Eriko KOBAYASHI, Hiroshi TANIGUCHI, Yuto MATSUURA, Hideki FUJIMOTO, Yoshihisa KOGA, Fumiko YASUNO, Tomomi SAKAI
Publikováno v:
Zen Nihon Shinkyu Gakkai zasshi (Journal of the Japan Society of Acupuncture and Moxibustion). 71:207-219
Autor:
Arisa MUKO, Hiroshi TANIGUCHI, Hideki FUJIMOTO, Yuto MATSUURA, Hirotsune KAIJIMA, Mikako KAIJIMA, Keiko TSUJIUCHI, Yoshihisa KOGA, Fumiko YASUNO, Tomomi SAKAI
Publikováno v:
Zen Nihon Shinkyu Gakkai zasshi (Journal of the Japan Society of Acupuncture and Moxibustion). 70:2-13
Autor:
Yasunori Hase, Kazutaka Ikegashira, Hiromasa Hashimoto, Takayuki Yamasaki, Iichiro Kawahara, Taku Ikenogami, Yoshihisa Koga, Koji Inagaki, Naoki Miyagawa, Takahiro Oka
Publikováno v:
Bioorganic & Medicinal Chemistry Letters. 29:873-877
Optimization of novel azetidine compounds, which we had found as colony stimulating factor-1 receptor (CSF-1R) Type II inhibitors, provided JTE-952 as a clinical candidate with high cellular activity (IC50 = 20 nM) and good pharmacokinetics profile.
Publikováno v:
Zen Nihon Shinkyu Gakkai zasshi (Journal of the Japan Society of Acupuncture and Moxibustion). 68:265-273
Autor:
Yoshinori Watanabe, Yoshihisa Koga, Yuto Matsuura, Tomomi Sakai, Fumiko Yasuno, Hideki Fujimoto, Satsuki Yamazaki
Publikováno v:
Zen Nihon Shinkyu Gakkai zasshi (Journal of the Japan Society of Acupuncture and Moxibustion). 68:199-207
Publikováno v:
Zen Nihon Shinkyu Gakkai zasshi (Journal of the Japan Society of Acupuncture and Moxibustion). 68:104-112
Publikováno v:
Zen Nihon Shinkyu Gakkai zasshi (Journal of the Japan Society of Acupuncture and Moxibustion). 67:124-132
Autor:
Yasunori Hase, Kazutaka Ikegashira, Takayuki Yamasaki, Satoki Doi, Taku Ikenogami, Koji Inagaki, Tsuyoshi Adachi, Hiromasa Hashimoto, Takayuki Yamaguchi, Yoshihisa Koga
Publikováno v:
Bioorganicmedicinal chemistry letters. 29(1)
We report the discovery of a novel azetidine scaffold for colony stimulating factor-1 receptor (CSF-1R) Type II inhibitors by using a structure-based drug design (SBDD) based on a docking model. The work leads to the representative compound 4a with h
Publikováno v:
Journal of Oral and Maxillofacial Surgery. 72:474-480
Purpose The combination of α2-adrenoceptor agonists, such as dexmedetomidine (DEX) and clonidine, with local anesthetics has been found to extend the duration of peripheral nerve blocks, probably owing to the resultant local vasoconstriction in the