Výsledky vyhledávání - "Yoshihisa Hama"

Successful and long-term response to trastuzumab plus paclitaxel combination therapy in human epidermal growth factor receptor 2-positive extramammary Paget's disease: A case report and review of the literature

Autor: Keiko Mamiya, Yoshihisa Hama, Takashi Kobayashi, Nodoka Sekiguchi, Daisuke Gomi, Tomonobu Koizumi, Toshirou Fukushima, Akiyuki Sakamoto, Shigeru Sasaki, Takashi Ichiyama

Publikováno v: Molecular and Clinical Oncology

A 58-year-old woman with a histologically confirmed diagnosis of vulvar extramammary Paget's disease (EMPD) was referred to our hospital due to locally advanced and relapsed EMPD. The patient had undergone surgical resection three times for relapsed

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::7455b0cee2f2be667098932eb0c070bc
https://doi.org/10.3892/mco.2017.1422

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Genetically engineered Bifidobacterium longum for tumor-targeting enzyme-prodrug therapy of autochthonous mammary tumors in rats

Autor: Takayuki Sasaki, Shun'ichiro Taniguchi, Yoshinori Hamaji, Ken-ichi Ito, Minoru Fujimori, Yoshihisa Hama, Jun Amano

Publikováno v: Cancer Science. 97:649-657

A fundamental obstacle in systemic therapy for cancer patients is the specific targeting of therapy directly to solid tumors. A strain of the domestic bacterium Bifidobacterium longum, which is non-pathogenic and anaerobic, showed selective localizat

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::4068c9721943383f103b55d231961bd6
https://doi.org/10.1111/j.1349-7006.2006.00221.x

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Increased Nuclear Localization of Transcription Factor Y-Box Binding Protein 1 Accompanied by Up-Regulation of P-glycoprotein in Breast Cancer Pretreated with Paclitaxel

Autor: Hiroshi Nakagomi, Muneaki Sano, Kiyoshi Shingu, Kazuma Maeno, Tomoyuki Fujita, Morihiko Kimura, Kimitoshi Kohno, Ken-ichi Ito, Minoru Fujimori, Shin-ichi Tsuchiya, Yoshihisa Hama, Hiroto Izumi

Publikováno v: Clinical Cancer Research. 11:8837-8844

Purpose: The Y-box binding protein 1 (YB-1) regulates expression of P-glycoprotein encoded by the MDR1 gene. There have been no previous studies regarding the involvement of YB-1 in the development of resistance to paclitaxel. The present study was d

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::6748ce78957bf39d123718247ec8c2f1
https://doi.org/10.1158/1078-0432.ccr-05-0945

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Can cytological findings predict intraductal spread of breast cancer? Histopathological case-control study

Autor: Minoru Fujimori, Shin-ichi Tsuchiya, Yoshihisa Hama, Takehiko Sakai, Ikuo Matsuyama

Publikováno v: Pathology International. 55:775-780

An important predictive factor for local recurrence after breast-conserving therapy is the state of the surgical margin. In order to obtain a negative surgical margin, the present case-control study was conducted to determine whether the extent of du

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c773f5ca709684d4fe23aa2960875580
https://doi.org/10.1111/j.1440-1827.2005.01905.x

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PREOPERATIVE DIAGNOSIS OF PARATHYROID CARCINOMA

Autor: Hiroshi Koyama, Kiyoshi Shingu, Toshiharu Kanai, Shinya Kobayashi, Yoshihisa Hama, Ken-ichi Ito, Minoru Fujimori, Yasuhiro Mochizuki

Publikováno v: Nihon Rinsho Geka Gakkai Zasshi (Journal of Japan Surgical Association). 65:2033-2036

原発性上皮小体機能亢進症(PHPT)の原因が上皮小体癌であることは稀であり,その術前診断は困難である.今回当科で経験した上皮小体癌症例の臨床的特徴を解析し,術前診断の指標となりう�

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::0af31be2eabe0dbe74fca087714018d4
https://doi.org/10.3919/jjsa.65.2033

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Mutation of the class I β-tubulin gene does not predict response to paclitaxel for breast cancer

Autor: Minoru Fujimori, Shin-ichi Tsuchiya, Morihiko Kimura, Muneaki Sano, Kiyoshi Shingu, Kazuma Maeno, Hiroshi Nakagomi, Ken-ichi Ito, Yoshihisa Hama

Publikováno v: Cancer Letters. 198:89-97

Mutation of the class I beta-tubulin gene has been reported to be one of the mechanisms that cause resistance to paclitaxel. To assess the relationship between paclitaxel-resistance and class I beta-tubulin gene mutation in breast cancer, Japanese pa

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::3f846d96fcc70e31d25a734bc6483108
https://doi.org/10.1016/s0304-3835(03)00279-9

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Stromal sarcoma of the breast with leiomyosarcomatous pattern

Autor: Minoru Fujimori, Ken Yamanda, Ritsu Kusama, Yasuhiro Mochizuki, Jun Amano, Ikuo Matsuyama, Yoshihisa Hama, Shin-ichi Tsuchiya, Ken-ichi Ito, Kiyoshi Shingu

Publikováno v: Pathology International. 52:534-539

We report an unusual case of stromal sarcoma of the breast with leiomyosarcomatous pattern, which recurred locally and was finally treated by radical mastectomy. The tumor was composed of pleomorphic and hyperchromatic spindle-shaped cells arranged i

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::6fa8abd529a03781e5afefe352def2d9
https://doi.org/10.1046/j.1440-1827.2002.01386.x

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The Rate of Tumour Growth Does Not Distinguish Between Malignant and Benign Thyroid Nodules

Autor: Jun Amano, Kazuhiko Asanuma, Yoshihisa Hama, Shinya Kobayashi, Minoru Fujimori, Shiro Yokoyama, Kiyosi Shingu

Publikováno v: The European Journal of Surgery. 167:102-105

Objective: To clarify whether or not the rate of tumour growth is a useful measure for distinguishing papillary thyroid cancer from benign nodules. Design: Retrospective study. Setting: Teaching hospital, Japan. Subjects: Fourteen patients with 27 no

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::4e79fbf090e7ea1206fdb1a6b5b092dd
https://doi.org/10.1080/110241501750070538

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