Zobrazeno 1 - 10
of 95
pro vyhledávání: '"Yoshihiro Miyahara"'
Autor:
Masahiro Matsumoto, Shinji Tashiro, Tatsumi Ito, Kazuya Takahashi, Gakuji Hashimoto, Junji Kajihara, Yoshihiro Miyahara, Hiroshi Shiku, Yoichi Katsumoto
Publikováno v:
Molecular Therapy: Methods & Clinical Development, Vol 30, Iss , Pp 367-376 (2023)
By analyzing patients treated with adoptive immune cell therapies, various immune cell phenotypes have been found in the starting and infused materials as determinants of sustained remission. The isolation of these specific phenotypes for clinical us
Externí odkaz:
https://doaj.org/article/2519a81bb32f4c479886bbd35c498d85
284 A novel hybrid T-cell receptor form of CAR-T cells showed enhanced activity against solid tumors
Publikováno v:
Journal for ImmunoTherapy of Cancer, Vol 11, Iss Suppl 1 (2023)
Externí odkaz:
https://doaj.org/article/01dd8d01e00943e89a0c047d8ea7692c
Autor:
Hiroaki Ikeda, Hiroshi Shiku, Shigehisa Kitano, Koji Kato, Shinichi Kageyama, Yoshihiro Miyahara, Mikiya Ishihara, Kazuto Takesako, Takashi Watanabe, Akihiko Matsumine, Makoto Endo, Tomomi Yamada, Satoshi Okumura, Naomi Kiyota, Kimikazu Yakushijin, Kohichi Takada, Shinichiro Kobayashi, Yasuhiro Nagata, Taizo Shiraishi, Keizo Horibe, Hiroshi Miwa
Publikováno v:
BMJ Open, Vol 12, Iss 11 (2022)
Introduction Adoptive cell transfer of genetically engineered T cells is a promising treatment for malignancies; however, there are few ideal cancer antigens expressed on the cell surface, and the development of chimeric antigen receptor T cells (CAR
Externí odkaz:
https://doaj.org/article/bb9809a70ebe4968b8c6ed77e521b719
Autor:
Takashi Kojima, Hiroaki Ikeda, Sachiko Okamoto, Junichi Mineno, Hiroshi Shiku, Shigehisa Kitano, Shinichi Kageyama, Yoshihiro Miyahara, Mikiya Ishihara, Daisuke Tomura, Ikuei Nukaya, Tetsuro Sasada, Noboru Yamamoto, Takashi Watanabe, Hideyuki Mishima, Alessandra Nardin, Evan Newell, Hidefumi Kato, Hiroyoshi Hattori, Takeru Funakoshi, Eiichi Sato, Hideto Chono, Muhammad Faris Kairi, Phuong Diem Hoang Nguyen, Yannick Simoni, Michael Fehlings
Publikováno v:
Journal for ImmunoTherapy of Cancer, Vol 10, Iss 6 (2022)
Externí odkaz:
https://doaj.org/article/abdfa23a1dce47a7a164f412340c65ed
Autor:
Mikiya Ishihara, Shinichi Kageyama, Yoshihiro Miyahara, Takeshi Ishikawa, Shugo Ueda, Norihito Soga, Hiroaki Naota, Katsumi Mukai, Naozumi Harada, Hiroaki Ikeda, Hiroshi Shiku
Publikováno v:
BMC Cancer, Vol 20, Iss 1, Pp 1-8 (2020)
Abstract Background Cancer testis (CT) antigens are promising targets for cancer immunotherapies such as cancer vaccines and genetically modified adoptive T cell therapy. In this study, we evaluated the expression of three CT antigens, melanoma-assoc
Externí odkaz:
https://doaj.org/article/20436dffba2045e08c3308ed02b352e7
Autor:
Hiroyasu Oda, Mikiya Ishihara, Yoshihiro Miyahara, Junko Nakamura, Yuji Kozuka, Motoh Iwasa, Akira Tsunoda, Yoshiki Yamashita, Kanako Saito, Toshiro Mizuno, Hiroshi Shiku, Naoyuki Katayama
Publikováno v:
Case Reports in Oncology, Vol 12, Iss 1, Pp 147-156 (2019)
Introduction: Cytokine release syndrome (CRS) is a potentially life-threatening systemic disease that has been observed after treatment with antibodies and adoptive T cell therapies. In this case, we observed nivolumab-induced CRS in a patient with g
Externí odkaz:
https://doaj.org/article/563f81c65b8d43e1b2a619e74b4549e8
Autor:
Keisuke Fujii, Yoshihiro Miyahara, Naozumi Harada, Daisuke Muraoka, Mitsuhiro Komura, Rui Yamaguchi, Hideo Yagita, Junko Nakamura, Sahoko Sugino, Satoshi Okumura, Seiya Imoto, Satoru Miyano, Hiroshi Shiku
Publikováno v:
OncoImmunology, Vol 6, Iss 5 (2017)
The CXCR3 ligands CXCL9, 10, and 11 play critical roles in the amplification of immune responses by recruiting CXCR3+ immune effector cells to the tumor site. Taking advantage of this property of CXCR3 ligands, we aimed to establish a novel approach
Externí odkaz:
https://doaj.org/article/26648c4bec8742d4aebf80ea73663b44
Autor:
Mithun Khattar, Yoshihiro Miyahara, Paul M Schroder, Aini Xie, Wenhao Chen, Stanislaw M Stepkowski
Publikováno v:
PLoS ONE, Vol 9, Iss 1, p e85882 (2014)
Optimal T cell activation and expansion require binding of the common gamma-chain (γc) cytokine Interleukin-2 (IL-2) to its cognate receptor that in turn engages a γc/Janus tyrosine kinase (Jak)3 signaling pathway. Because of its restricted express
Externí odkaz:
https://doaj.org/article/dfc770baab604d759e9b2c8410d641e7
Autor:
Kenshiro Tsuda, Keiichi Yamanaka, Wang Linan, Yoshihiro Miyahara, Tomoko Akeda, Takehisa Nakanishi, Hiroshi Kitagawa, Masato Kakeda, Ichiro Kurokawa, Hiroshi Shiku, Esteban C Gabazza, Hitoshi Mizutani
Publikováno v:
PLoS ONE, Vol 6, Iss 12, p e29020 (2011)
Malignant melanoma (MM) is an aggressive cutaneous malignancy associated with poor prognosis; many putatively therapeutic agents have been administered, but with mostly unsuccessful results. Propionibacterium acnes (P. acnes) is an aerotolerant anaer
Externí odkaz:
https://doaj.org/article/990c1f9ba769498cb759b829098ed7e3
Autor:
Mikiya Ishihara, Yoshihiro Nishida, Shigehisa Kitano, Akira Kawai, Daisuke Muraoka, Fumiyasu Momose, Naozumi Harada, Yoshihiro Miyahara, Naohiro Seo, Hiroyoshi Hattori, Kohichi Takada, Makoto Emori, Shigeki Kakunaga, Makoto Endo, Yoshihiro Matsumoto, Tetsuro Sasada, Eiichi Sato, Tomomi Yamada, Akihiko Matsumine, Yasuhiro Nagata, Takashi Watanabe, Shinichi Kageyama, Hiroshi Shiku
Publikováno v:
International Journal of Cancer. 152:2554-2566
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::f443ad8f36f19a7feb33e61a77b4ccd7
https://doi.org/10.1002/ijc.34453
https://doi.org/10.1002/ijc.34453